What is Allopurinol?

Allopurinol is a medicine mainly used in a condition in which there is an excess production of uric acid in the body.

Manufactured By – Glaxosmithkline Pharmaceuticals Ltd

What is Allopurinol used for?

Allopurinol is used in:

  • Decreasing uric acid level in your body
  • Swelling and pain of the small joints (gout)
  • Kidney stones
  • An increased uric acid level in chemotherapy

How Does Allopurinol Work?

Allopurinol reduces the speed of the chemical reactions that occur in the body to produce uric acid. Thus, allopurinol reduces uric acid level in your urine and blood.

How to Take Allopurinol?

  • Take Allopurinol tablet as a whole with a glass of water.
  • Do not crush, chew or break the tablet while consuming it.
  • It is preferable to consume Allopurinol after a meal.

Common Dosage for Allopurinol?

It is generally prescribed once or twice daily. Your doctor may alter your dosage and its frequency depending upon the severity of your condition.

When to Avoid Allopurinol?

Avoid Allopurinol if:

  • You have heart problems
  • You have high blood pressure
  • You are suffering from thyroid dysfunction
  • You are lactose intolerant

Side-Effects of Allopurinol

Some of the reported side effects of Allopurinol are:

  • Vomiting
  • Diarrhea
  • Drowsiness
  • A headache
  • Changes in your sense of taste
  • Muscle pain
  • Unusual urination

Effects of Allopurinol on Organs?

Long-term use of Allopurinol may cause damage to your kidneys and liver. Your doctor may adjust your dosage if you have any of these conditions.

Are There Any Reported Allergic Reactions?

Skin rashes are the most common allergic reaction reported with use of Allopurinol. These rashes may be severe accompanied by fever, headache, and sore throat. Other allergic reactions include itching of skin, swelling of any part of face, tongue or throat, and shortness of breath.

Drug Interactions to Be Careful About

One needs to be careful of the following drug interactions when consuming Allopurinol:

  • Diuretics
  • ACE-inhibitors (blood pressure lowering medication)
  • Antacids
  • Azathioprine
  • Aspirin
  • Theophylline
  • Phenytoin
  • Antibiotics
  • HIV medication
  • Immunosuppressant
  • Blood thinning medications
  • Aluminium hydroxide

Effects/Results After Consuming Allopurinol

The effect of Allopurinol tablet can be seen in about 2 to 3 days. The average duration of action of this tablet is nearly 24 hours.

Things to Know About Olanzapine


Is Allopurinol addictive?

No habit forming tendency has been reported with Allopurinol.

Can I have Allopurinol with alcohol?

It is better to avoid alcohol when on Allopurinol. Consult your doctor about limiting alcohol with this medication.

Any particular food item to be avoided?

You must consult your doctor regarding the foods to be avoided.

Can I have Allopurinol when pregnant?

In most cases, it is not safe to take Allopurinol if you are pregnant or planning a pregnancy. Consult your doctor if it is absolutely necessary to take this medication.

Can I have Allopurinol when feeding a baby?

Allopurinol is known to pass in mother’s milk to the baby. Consult your doctor if it is absolutely necessary to take this medication while you are breastfeeding.

Can I drive after taking Allopurinol?

It is generally safe to drive while taking Allopurinol. However, if you experience drowsiness, dizziness, a headache or any side effect that alters your consciousness then it may not be safe to drive.

What happens if I overdose on Allopurinol?

An overdose of Allopurinol will not improve your symptoms. It may even cause serious side-effects like stomach pain, nausea, vomiting, and diarrhea. Consult your doctor immediately in case of overdose.

What happens if I eat expired Allopurinol?

If by mistake you consume a dose of expired Olanzapine tablet, the chances of harm are very less. It is advised to check the label for expiry date always before use.

What happens if I miss a dose of Allopurinol?

As soon as you remember, take the missed dose. However, if it is already time for the next dose, carry on with your regular schedule. Do not take a double dose to make up for the missed dose.

Storage Requirements for Allopurinol

  • Always store Allopurinol at a temperature around 25 degree Celsius
  • Storing in moisture prone places like bathroom may damage the tablet
  • Keep this medicine away from direct heat and sunlight
  • Store it where your children and pets can’t reach

Pro Tips When Taking Allopurinol

  • Do not try to self-adjust the dose. Take it in the quantity prescribed by your doctor.
  • Do not share your medication with anyone even if they have a similar condition.
  • Discuss the pros and cons of Allopurinol if you are pregnant or planning a pregnancy or if you are breastfeeding.
  • Taking Zyloric tablet along with aluminium hydroxide may decrease the effect of Zyloric. Maintain a gap of at least 3 hours between the administrations of these two.
  • Monitor your blood count regularly while on Allopurinol.
  • Elderly patients with liver or kidney dysfunction may be prescribed with a low dose at longer intervals.
  • It is recommended to drink a lot of water (about 2 to 3 liters) to prevent dehydration.
  • Do not try to self-adjust the dose. Take it in the quantity prescribed by your doctor.

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