Amikacin: Uses, Dosage, Price, Side Effects, Precautions & More

Amikacin: Uses, Dosage, Price, Side Effects, Precautions & More

Amikacin Composition – Amikacin (500mg)
Manufactured By – Aristo Pharmaceuticals Pvt Ltd
Prescription – Prescription Required
Form – Injection
Price – Rs 89
Quantity – 2 ml in 1 vial

What is Amikacin?

  • Amikacin belongs to “aminoglycoside” group of antibiotics which is used to treat different kinds of bacterial infections.

Amikacin is commonly used in treatment or prevention of following diseases or symptoms:

  • Bacterial septicemia (including neonatal sepsis);
  • Infections of the respiratory tract,
  • Infections of bones and joints,
  • Infections of central nervous system (including meningitis)
  • Skin and soft tissue infections;
  • Intra-abdominal infections (including peritonitis);
  • Burns and postoperative infections (including post-vascular surgery).
  • Complicated and recurrent urinary tract infections
  • Infectious diarrhea
  • Typhoid (enteric fever)
  • Infections of ear, throat, tonsils etc
  • Gonorrhoea

Amikacin may also be used for other purposes not mentioned above.

Manufactured By – Prem Pharmaceuticals Pvt Ltd

Buy & Get Minimum 20% Discount: Myra | Netmeds

How does Amikacin work?

  • Amikacin belongs to aminoglycoside group of antibiotics which are considered to be bactericidal (bacterial killing ability).
  • Aminoglycosides disrupt the synthesis of proteins, thus killing the bacteria and checking its growth.

Amikacin Price in India

Specifics Amikacin Price
250 mg Vial of 1 Injection Rs 36
500 mg vial of 2 ml Injection Rs 11.87
Also Read: Cephalexin price | Clopidogrel Price

How to Take Amikacin?

  • In order to reduce antibiotic resistance and increase the effectiveness of Amikacin, it is advisable that all antibacterial therapies including Amikacin should be selected based on culture and susceptibility information (a particular antibiotic should only be used to treat or prevent infections that are strongly suspected to be caused by susceptible bacteria),
  • Available in the form of sterile, colorless to light straw colored solution.
  • Amikacin is injected to the patient by a healthcare professional.

Common Dosage for Amikacin?

The drug dosage and form is decided by the physician based upon:

  • age and body weight of the patient
  • health status/medical condition of the patient
  • disease severity
  • reaction to the first dose
  • history of allergy/drug reactions
Also Read: Atorvastatin Dosage

When to Avoid Amikacin?

Amikacin is ineffective in treating viral infections like common cold, flu etc. Overuse or unnecessary usage may cause antibiotic resistance or decreased effectiveness of antibiotic

Amikacin should not be used in:

Patients allergic to Amikacin

If you are allergic to drugs belonging to aminoglycoside family like gentamicin.

In patients suffering from Myasthenia Gravis

Pregnant females

Nursing women

Side-effects of Amikacin?

Side effects are possible but do not always occur in all the patients. Treatment with amikacin for more than 10 days has not been established as being safe. Side effects increases with advanced age and prolonged use.

The most common side effect is local pain with intramuscular injections.

  • Diarrhea
  • Proteinuria – Loss of proteins in urine.
  • Nephrotoxicity: Kidney function changes should be closely monitored in patients
  • Hearing loss
  • Vertigo, imbalance, dizziness.
  • Electrolyte abnormalities.
  • Nausea and vomiting
  • Headache, drug fever
  • Rare: Neuropathy, rashes.

Reported Allergic Reactions?

Although Amikacin is used to treat bacterial infections but an allergic reaction to Amikacin might occur.

Possible allergic reactions reported include: itchy skin, rashes, swelling especially on face, lips & throat, difficulty in breathing or swallowing and loss of consciousness.

Effect on organs

  • Use in kidney disease: Use with caution. Concentrations should be monitored for patients with impaired kidney function.
  • Presumed to be safe in severe liver disease; however, use with caution in patients with severe liver disease.

Drug Interactions to Be Careful About

  • All the possible drug interactions might not be listed here. You must always inform the physician of all the drugs/products you use.
  • You must inform your doctor if you frequently use other drugs that make you drowsy or sleepy, such as sleeping pills, other allergy drugs, narcotic pain medicine, muscle relaxants, and drugs used for fits, depression, or anti-anxiety drugs.
  • You must also inform about the herbal products that you are consuming. You must not modify the drug regimen without your doctor’s approval.
  • Some of the common drugs which interact with Amikacin include:
  • Co-administration of loop diuretics (furosemide)
  • Other aminoglycoside antibiotics
  • polymyxin B,
  • colistin,
  • cisplatin,
  • vancomycin,
  • amphotericin B,
  • clindamycin,
  • cephalosporins,
  • succinylcholine,
  • tubocurarine,
  • decamethonium,
  • halogenated hydrocarbon inhalation anaesthetics,
  • opioid analgesics
  • penicillin

Shows Effects / Results In:

The time taken for Amikacin to show its effect depends upon its intended use.

FAQ

Is Amikacin Addictive?

No such tendency has been reported.

Can I have Amikacin with alcohol?

The effect of alcohol with Amikacin is not clear. Consult your doctor before consumption.

Any particular food item to be avoided?

No

Can I have Amikacin When Pregnant?

Always inform your doctor if you are pregnant or plan to become pregnant.

The medicine should be used with great caution during pregnancy as it may have adverse effects on the foetus

Can I have Amikacin when feeding a baby?

Always inform your doctor if you are breast-feeding your child.

It is not known whether amikacin is excreted in breast milk.

Since the possible harmful effect on the infant is not known, it is recommended that if nursing mothers must be given amikacin, the infants should not be breast fed during therapy

Can I drive after taking Amikacin?

Amikacin usually does not affect your ability to drive.

However, few patients might experience dizziness as a side effect, in such cases it should be used with caution while driving.

Storage Requirements for Amikacin

-Store at 20 to 25C (68 to 77F).

– Protect from light

Pro tips

Amikacin is present in high concentrations in the urine excretory system; therefore, patients should be well hydrated to minimize irritation/damage of the kidney tubules.

Also Read: Acyclovir | Carbamazepine

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