A blister, which is also called a vesicle by medical professionals, is a raised portion of skin that is filled with fluid. You’re probably familiar with blisters if you’ve ever worn ill-fitting shoes for too long.

This common cause of blistering produces vesicles when friction between your skin and the shoe results in layers of skin separating and filling with fluid.

Blisters are often annoying, painful, or uncomfortable. But in most cases, they aren’t a symptom of anything serious and will heal without any medical intervention. If you ever have unexplained blistering on your skin, you should see your healthcare provider for a diagnosis.

There are many temporary causes of blisters. Friction occurs when something rubs against your skin for a prolonged period of time. This happens most commonly on hands and feet.

Contact dermatitis can also cause blisters. This is a skin reaction to allergens, like poison ivy, latex, adhesives, or irritants like chemicals or pesticides. It can cause red, inflamed skin and blistering.

Burns, if severe enough, can produce blistering. This includes burns from heat, chemicals, and sunburns.

Allergic eczema is a skin condition that is caused or worsened by allergens and can produce blisters. Another type of eczema, dyshidrotic eczema, also results in blistering; but its cause is unknown, and it tends to come and go.

Frostbite is less common, but it can cause blisters on skin that’s exposed to extreme cold for a prolonged period of time.

Blistering can also be a symptom of certain infections, including the following:

  • Impetigo, a bacterial infection of the skin that can occur in both children and adults, may cause blisters.
  • Chickenpox, an infection caused by a virus, produces itchy spots and often blisters on the skin.

The same virus that causes chickenpox also causes shingles, or herpes zoster. The virus reappears in some people later in life and produces a skin rash with fluid vesicles that can rupture.

Herpes and the resulting cold sores can lead to skin blistering.

Treatment for blisters :

  • Most blisters require no treatment. If you leave them alone, they will go away, and the top skin layers prevent will infection.
  • If you know the cause of your blister, you may be able to treat it by covering it with bandages to keep it protected. Eventually the fluids will seep back into the tissue, and the blister will disappear.
  • You shouldn’t puncture a blister unless it is very painful, as the skin over the fluid protects you from infection. Blisters caused by friction, allergens, and burns are temporary reactions to stimuli. In these cases, the best treatment is to avoid what is causing your skin to blister.
  • The blisters caused by infections are also temporary, but they may require treatment. If you suspect you have some type of infection, you should see your healthcare provider.

In addition to medication for the infection, your healthcare provider may be able to give you something to treat the symptoms. If there is a known cause for the blisters, such as contact with a certain chemical or use of a drug, discontinue use of that product.

Some conditions that can cause blisters, such as pemphigus, don’t have a cure. Your healthcare provider can prescribe treatments that will help you manage symptoms. This may include steroid creams to relieve skin rashes or antibiotics to cure skin infections.

Top 13 Medicines for Blisters in India (Tablets, Syrups, Ointment & More)

1) Calendula: Heals blisters

  • Brand name – Calendula ointment
  • Composition – Calendula plant extract
  • Popularity level – 9

Calendula’s wound-healing properties are due to the presence of essential oils, saponins, flavonoids and alkaloids. These compounds have been shown to promote healing of blisters.

  • Dosage: Apply a thin layer of Calendula Ointment to affected area 3 times a day or as needed.
  • Price: A 30g tube of the ointment costs $15.

2) Natura All Heal Plus: Cures blisters

  • Brand name – Natura All Heal Plus
  • Composition – Each 0.2g contains:Calendula officinalis D3; Benzoinated lard 10.8 mg; Echinacea angustifolia D3; Eucalyptus oil 4.86 mg; Hamamelis virginiana D3; Kaolin 22.2mg; Natrum muriaticum D3; Tamus cummunis D3; Tincture benzoin 6.25mg; Stellaria media 5.4mg; Symphytum officinale 5.4mg; Zinc oxide 5.5mg; Methyl parahydroxybenzoate 0.15%; Propyl parahydroxybenzoate 0.05%.
  • Popularity level – 7

All Heal Plus (Ointment) is a homoeopathic medicine which acts as a topical skin antiseptic and assists in the treatment of: abrasions; boils; blisters; insect bites; skin ulcers; septic wounds; slow healing wounds; minor localised skin infections; localised inflammatory skin conditions. Calendula officinalis is a topical antibacterial that promotes rapid healing of superficial injuries, open wounds, skin abrasions, cuts, scalds and burns.Echinacea angustifolia has antibacterial, antiviral and anti-inflammatory properties and assists in the treatment of superficial injuries and topical inflammation, boils, recurring carbuncles, irritation from insect bites. It also has strong immunostimulant properties to help treat and counter the spread of infection. Hamamelis virginana acts primarily on the muscular walls of veins to improve circulation, relieve venous congestion, inflammations and burns. Natrum muriaticum helps to relieve dry or crusty eruptions on the skin, itchy skin, hives and fever blisters. Stellaria media has anti-inflammatory properties and assists in the relief of gout, rheumatism and all superficial inflammation with redness. Symphytum officinale has significant anti-inflammatory activity for topical treatment of minor wounds, skin inflammations, ulcers, sprains, strains and bruises.

  • Dosage: Apply a thin layer of the ointment on the affected area, two to three times a day.
  • Price: A 50g tube of the ointment costs ₹129.

3) Blister pads: Protect blisters and promote healing

  • Brand name – Spenco 2nd Skin Blister Pads
  • Composition – Hydrocolloid pad
  • Popularity level – 8

The Spenco 2nd Skin Blister Pads promote a scab free, naturally healed blister. A thin hydrocolloid pad and adhesive film stays in place up to 5 days. Can also be used to prevent blisters. Each pad is waterproof, and provides a barrier to bacteria. Lightweight and easy to apply; perfect for backpacking and hiking.

  • Dosage: Apply the pack on the affected area, each application lasts up to 5 days.
  • Price: A pack of 5 – Sterile Hydrocolloid Pads, (60mm x 38mm) cost $7.77.

4) Zincuta ointment: Heals poison Ivy blisters

  • Composition – axungia (soft fat used in medicine as an emollient), styrax benzoin resin extract (a resin extract from the tree that soothes and heal wounds), beeswax (retains the skin’s natural moisture to relieve itchiness), and slippery elm bark (minimizes inflammation and itchiness)
  • Popularity level – 7

The natural blister ointment has antibacterial and antiseptic properties which help to calm and heal blister; a thin layer of it on the affected area will immediately relieve soreness and promote healing. Made of natural ingredients of the purest forms. Zincuta skin healing ointment is formulated with various natural ingredients. Axungia: a type of soft fat that’s used in medicine as an emollient. Styrax benzoin resin: this is a resin extract from the tree; it soothes and heal wounds. Beeswax: retains the skin’s natural moisture to relieve itchiness. Slippery elm bark: minimizes inflammation and itchiness.

  • Dosage: Apply a thin layer of the ointment on the affected area, three times a day.
  • Price: A 2 oz tube of the ointment costs $12.

5) Oleavicin cream: Cures fever blisters

  • Brand name – Oleavicin cream
  • Composition – Menthol (0.3%) – Analgesic Inactive Ingredients: Extra Virgin Olea Europaea (Olive) Oil, Cera Alba (Beeswax), Ricinus Communis (castor) Seed Oil, Aloe Barbadensis Leaf Juice, Propolis Extract, Olea Europaea (Olive) Leaf Extract, Symphytum Officinale (Comfrey) Extract, Calendul Officinalis Flower Extract, Hypericum Perforatum (St. John’s Wort), Natural Flavor, Rosmarinus Officinalis (Rosemart) Extract, Tocopherol (Vitamin E), Allantoin, Lavandula Angustifolia (Lavender) Oil.
  • Popularity level – 9

This cream contains all natural ingredients that promote healing of fever blisters.

  • Dosage: Apply a thin layer of the cream on the affected area, three times a day.
  • Price: A 1 oz tube of the cream costs $4.55

6) Cramer Skin Lube: Prevents blisters

  • Brand name – Cramer Skin Lube
  • Composition – Petrolatum, zinc stearate, silicone, propylene glycol, diazolidinyl uria, Methyl Paraben, Propyl Paraben.
  • Popularity level – 5

Cramer Skin Lube is designed to prevent blisters and burns in areas of the body that experience high friction. It reduces chaffing by lubricating the skin and decreasing friction during rapid movments. It stay on the skin during heavy use and doesn’t run off due to sweat making it long-lasting and effective.

  • Dosage: Apply the lube on friction prone areas to prevent blisters.
  • Price: A 1 pound can the lube costs $22

7) Skin Slick Spray: Prevents blisters

  • Brand name – Skin Slick Spray
  • Composition -silicone based
  • Popularity level – 8

Skin Slick a continuous spray skin lubricant is an innovative solution to eliminate skin chafing, blistering, and friction. Skin Slick acts as a second skin.

  • Dose : Apply a single spray, directly on prone to problem areas,
  • Price: A 3oz bottle of the spray costs $22.

8) Docosanol: Cures blisters

  • Brand name – Abreva cream
  • Composition – Docosanol
  • Popularity level – 5

Docosanol is used to treat “cold sores/fever blisters” (herpes labialis). It can speed up healing of the sores and decrease symptoms (such as tingling, pain, burning, itching). It works by blocking the virus that causes the cold sores (herpes simplex) from entering the healthy skin cells and growing in number. This medication does not cure herpes and does not prevent passing the infection to someone else. It does not prevent a future occurrence.

Dosage: Follow all directions on the product package, or use as directed by your doctor. Use this medication at the first signs of a cold sore (such as tingling, burning, redness, or a bump). Wash and dry your hands before applying the medication. Clean and dry the affected areas. Apply a thin layer of medication to completely cover the area of the cold sore or the area of tingling/itching/redness/swelling and rub in gently, usually 5 times a day every 3-4 hours, or as directed by your doctor. Wash your hands with soap and water after applying. If you are uncertain about any of the information, consult your doctor or pharmacist.

Price: A 2g tube of the cream costs $20.99

9) Hyland’s cold sores and fever blisters: Cures fever blisters

  • Brand name – Hyland’s cold sores and fever blisters
  • Composition – Antimonium Crudum 6X HPUSdry or cracked lips, canker soresBaptisia Tinctoria 6X HPUSsores in mouthBorax 3X HPUScold sores, blisters in mouthNaturm Muriaticum 3X HPUSdry lips, cracked lips, cold sores
  • Popularity level – 6

This Homeopathic medicine is used for relief of symptoms of cold sores, cracked lips and fever blisters due to common cold or exposure. Also useful in canker sores and mouth ulcers due to acid foods.

  • Dosage: Adults and children 12 years and over: Dissolve 2-3 tablets under tongue every 4 hours or as needed. Children 6 to under 12 years old: 1/2 adult dose.
  • Price: A bottle of 100 tablets cost $10.59

10) Dr Scholls Moleskin: Cures pain due to blisters

  • Brand name – Dr. Scholls Moleskin Plus Padding
  • Composition – Adhesive pads
  • Popularity level – 6

Dr. Scholls Moleskin Plus Padding is designed to help alleviate pain from blisters, bunions, calluses and corns with adhesive padding that provides all-day pain relief. And it comes in a roll with more Moleskin for larger areas.

  • Dosage: Cut a suitable size from the roll and apply on the affected area.
  • Price: Dr. Scholl’s Moleskin Plus 24″ x 4 5/8″ Padding Roll, 1 Count costs ₹802.

11) SBL Curoplus Ointment: Heals blisters

  • Brand name – SBL Curoplus Ointment
  • Composition – Calendula officinalis Q 2% v/w, hamamelis virginica Q 2% v/w, Echincea angustifolia Q 0.5% v/w, Bellis perennis Q 1.0% v/w, Berberis aquifolium Q 1.0% v/w and Stabilised cream base q.s.
  • Popularity level – 7

Calendula officinalis– Calendula officinalis has potent anti- inflammatory and moisturizing properties. It is beneficial for dry or damaged skin as it greatly heals, soothes, and softens skin and acts as a natural antiseptic.

Hamamelis virginica– It has anti-inflammatory properties, It reduces the healing time from acne, sunburn, and help with preventing skin peeling and flaking.

Berberis aquifolium– Berberis is a useful herb for clearing acne, pimple, scar marks. It lightens blotches and brown spots.

  • Dosage: Apply a thin layer of the cream over the affected area.
  • Price: A 25g tube of the cream costs ₹80.


12) Purao Biomedi gel: Heals blisters

  • Composition – Manuka Honey
  • Popularity level – 5

PURAO BIOMEDI+ SKIN AID GEL is a natural wound healing and protection gel used externally only, and an excellent product for the first-aid kit. It contains Medical Grade Manuka Honey and is 100% natural. This gel is easy to apply, creates a moist, low pH environment that promotes new tissue formation and wound healing.

  • Dosage: Apply a thin layer of the gel on the affected area.
  • Price: A 25 ml bottle of the gel costs £12

13) Healaid Cream: Heals blisters

  • Brand name – Healaid Cream
  • Composition – 1% w/w phenol, 0.5% w/w boric acid, 5% w/w zinc oxide and 0.8% w/w tea tree oil
  • Popularity level – 7

Healaid Cream contains Boric Acid as an active ingredient. Healaid Cream works by inhibiting the bacterial and fungal growth; exact mechanism of action unknown. It is used for general relief of blisters, sunburn, cuts, nappy rash, sores and haemorrhoids. It effectively aids in the healing process.

Dosage: Apply a thin layer of the cream on the affected area, three times a day.


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