List of 21 Best Medicines for Constipation – Composition, Dosage, Popularity & More (2019)

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List of 21 Best Medicines for Cold - Composition, Dosage, Popularity & More (2019)

Constipation is a condition of the digestive system where an individual has hard feces that are difficult to expel. In most cases, this occurs because the colon has absorbed too much water from the food that is in the colon.

The slower the food moves through the digestive tract, the more water the colon will absorb from it. Consequently, the feces become dry and hard. When this happens, emptying the bowels can become very painful.

The main symptoms of constipation are increased difficulty and straining when passing stools.

Constipation occurs when the colon (also called the large bowel or large intestine) absorbs too much water, or when food moves too slowly through the colon, resulting in dry, hard stool.

Irregular bowel habits, childbirth, and surgery increase the risk for constipation. Disruptions in daily routines (e.g., travel) also can increase the risk. Other risk factors and conditions that can cause constipation include the following:

  • Anxiety, fear, excessive worry
  • Cancer (e.g., colorectal cancer, anal cancer)
  • Certain medications (e.g., narcotic pain relievers, calcium channel blockers, antidepressants) and supplements (e.g., iron, calcium)
  • Diabetes
  • Excessive use of laxatives
  • Improper diet (e.g., inadequate dietary fiber, inadequate fluid intake)
  • Intestinal obstruction or conditions (e.g., irritable bowel syndrome, diverticular disease)
  • Muscle disorders (e.g., weakness, spasticity)
  • Neurological disorders (e.g., stroke, multiple sclerosis [MS], Parkinson’s disease, spinal cord injury)
  • Pregnancy
  • Sedentary life style, lack of exercise
  • Systemic diseases (e.g., lupus, scleroderma)

Passing fewer stools than usual can be a sign of constipation.

Most cases of constipation respond to conservative treatment, such as dietary and exercise changes or mild laxatives.

Your doctor will probably start treatment by recommending more fiber or bulk in your diet. Over-the-counter laxatives are generally safe to use, with few side effects. However, as with any OTC medication, it is very important to read the instructions on the drug label carefully, take the drug as recommended on the label, and not exceed the maximum dose. Overusing laxatives can lead to potentially serious side effects.


List of Top 21 Medicines for Constipation

  1. Psyllium
  2. Ispaghula
  3. Methylcellulose
  4. Fibril
  5. Docusates
  6. Phenolphthalein
  7. Bisacodyl
  8. Sodium picosulfate
  9. Senna
  10. Agarcol
  11. Cremaffin
  12. Cremaffin pink
  13. Julax
  14. Pursennid
  15. Lactulose
  16. Prucalopride
  17. Lubiprostone
  18. Castor oil
  19. Epsom salt and Glauber’s salt
  20. Sodium phosphate
  21. Softovac Powder

Top 21 Medicines for Constipation in India (Tablets, Syrups & More)

1. Psyllium: Cures mild constipation

  • Brand name – Organic India psyllium
  • Composition Psyllium (Plantago) husk
  • Popularity level – 4
  • Psyllium is a dietary fiber. It absorbs water and increases the bulk of stool, thus aiding in bowel evacuation.
  • Dosage – Mix 3-8g of the medicine with cold milk, fruit juice or water. Take once or twice daily.
  • Price – A pack of 100g of the powder costs ₹200.

2. Ispaghula: Cures mild constipation

  • Brand name -Dabur Sat Isabghol
  • Composition – Ispaghula husk
  • Popularity level – 5
  • Ispaghula is a dietary fibre. It absorbs water and increases bulk of stool, thus aiding in bowel evacuation.
  • Dosage –  Mix 3-8g of the medicine with cold milk, fruit juice or water. Take once or twice daily.
  • Price – A pack of 200g of the powder costs ₹126.

3. Methylcellulose: Cures mild constipation

  • Brand name – Celevac 500mg
  • Composition – Methylcellulose 500mg
  • Popularity level – 5
  • Methylcellulose is a bulk-forming laxative that increases the amount of water in your stools to help make them softer and easier to pass. Methylcellulose is used to treat constipation and to help maintain regular bowel movements.
  • Dosage – Take one tablet with a glass of lukewarm water, preferably before bed.
  • Price – A pack of 112 tablets cost £10.

4. Fibril: Cures mild constipation

  • Brand name – Fibril, Isogel, Fybogel
  • Composition – Psyllium and Ispaghula husk
  • Popularity level – 5
  • Psyllium and Ispaghula in combination help better to evacuate bowels.
  • Dosage –  Mix 4-6g of the medicine with cold milk, fruit juice or water. Take once or twice daily.
  • Price – A pack of 100g of the powder costs ₹80.

5. Docusates: Cures mild to moderate constipation

  • Brand name – Cellubril, Doslax
  • Composition – Dioctyl sodium sulfosuccinate
  • Popularity level – 3
  • Docusates is an anionic detergent. This drug acts as a mild laxative.  It softens stool by accumulating water in the intestines.
  • Price – A pack of 6 Cellubril 100mg tablets costs ₹7.

6. Phenolphthalein: Cures moderate to severe constipation

  • Brand name – Laxil
  • Composition – Phenolphthalein
  • Popularity level – 1
  • Phenolphthalein is a stimulant purgative. It irritates the intestinal mucosa and thus helps in enhancing the peristaltic movement of the intestines.
  • Dosage –  60-130mg with lukewarm water, to be taken at bedtime.
  • Price – A bottle of 200ml of the syrup costs ₹120.

7. Bisacodyl: Cures moderate to severe constipation

  • Brand name – Dulcolax, Conlax
  • Composition – Bisacodyl
  • Popularity level – 8
  • Bisacodyl acts as a purgative. It irritates the intestinal mucosa and thus stimulates motor activity in the colon.
  • Dosage –  One tablet with lukewarm water, to be taken at bedtime.
  • Price – A pack of 10 tablets of Dulcolax cost ₹15.

8. Sodium picosulfate: Cures severe constipation

  • Brand name – Cremalax, Laxicare
  • Composition – Sodium picosulfate
  • Popularity level – 6
  • Sodium picosulfate irritates the intestinal mucosa and also activates myenteric plexus directly, thus increasing gut motility.
  • Dosage –  5-10mg at bedtime.
  • Price – A pack of 15 tablets of Cremalax 10mg costs ₹120.

9. Senna: Cures mild to moderate constipation

  • Brand name – Glaxenna, Pursennid, Softsena
  • CompositionSenna leaf powder
  • Popularity level – 3
  • Senna contains anthraquinone glycosides also known as emodins. In the colon, bacteria liberates the active anthro form from emodins. This acts locally and also activates myenteric plexus, thereby aiding in bowel evacuation. The medicine is usually taken at bedtime. Softly formed evacuation occurs in the morning.
  • Dosage –  3-5g of the medicine is to be taken with lukewarm water, at bedtime.
  • Price – A pack of 10 tablets of Glaxenna costs ₹4.

10. Agarcol: Cures severe constipation

  • Brand name – Agarcol suspension
  • Composition – Liquid paraffin and phenolphthalein
  • Popularity level – 5
  • This combination medicine helps to soften the stool and thus aid bowel evacuation.
  • Dosage – 2-3 tablespoons of the emulsion should be taken with lukewarm water, before bedtime.

11. Cremaffin: Cures chronic constipation

  • Brand nameCremaffin
  • Composition – Milk of magnesia and liquid paraffin
  • Popularity level – 8
  • Liquid paraffin helps to soften stool and milk of magnesia helps to retain water osmotically. This medicine generally used for treating chronic constipation.
  • Dosage –  2-3 tablespoons of the emulsion should be taken with lukewarm water, preferably before a meal.
  • Price – A bottle of 170ml of the syrup costs ₹84.

12. Cremaffin pink: Cures chronic constipation

  • Brand name – Cremaffin pink
  • Composition – Phenolphthalein, Milk of magnesia and liquid paraffin
  • Popularity level – 6
  • This combination medicine helps to relieve chronic and severe constipation.
  • Dosage – 1-2 tablespoons of the emulsion should be taken with lukewarm water, preferably before a meal.
  • Price – A bottle of 200 ml of the syrup costs ₹168.

13. Julax: Cures chronic constipation

  • Brand name – Julax
  • Composition – Bisacodyl and Casanthrol
  • Popularity level – 5
  • This combination medicine works by increasing gut motility.  It is used for treating chronic constipation.
  • Dosage –  One tablet, twice daily or as prescribed by a doctor.
  • Price – A pack of 10 tablets cost ₹40.

14. Pursennid: Cures chronic constipation

  • Brand name – Pursennid
  • Composition – Senna and Docusates
  • Popularity level – 4
  • This combination medicine helps to soften stool and also increase gut motility.
  • Dosage – One tablet twice daily, once at bedtime and other in the morning or as prescribed by a doctor.
  • Price – A pack of 30 tablets cost €7.2

15. Lactulose: Cures mild to moderate constipation

  • Brand name – Livo-luk, Lacsam, Duphalac
  • CompositionLactulose
  • Popularity level – 7
  • Lactulose is a semisynthetic disaccharide of fructose and lactose, which is neither digested nor absorbed in the small intestine. Broken in the colon by bacteria to osmotically more active product, thus it helps to retain water. It helps in evacuation of a soft stool.
  • Dosage –  10g of the medicine should be taken twice daily with water.
  • Price – A bottle of 100ml of the syrup costs ₹102.

16. Prucalopride: Cures chronic constipation

  • Brand name – Prudac, Resolor
  • Composition – Prucalopride
  • Popularity level – 5
  • Prucalopride is a selective 5HT-4 receptor agonist, thus it increases propulsive movement in the intestines. This medicine is used for treating chronic constipation and constipation-predominant IBS.
  • Dosage –  1-2 mg of the medicine should be taken once in a day.
  • Price – A pack of 10 tablets costs ₹250.

17. Lubiprostone: Cures chronic constipation

  • Brand name – Amitiza
  • Composition – Lubiprostone
  • Popularity level – 4
  • Lubiprostone is a PG analog and EP4 receptor agonist, thus it stimulates mucosal chloride channels and increases intestinal secretion. This medicine is used for treating chronic constipation and constipation-predominant IBS.
  • Dosage –  1-2 mg of the medicine should be taken once in a day.
  • Price – The cost for Amitiza oral capsule 8 mcg is around $396 for a supply of 60 capsules.

18. Castor oil: Cures moderate to severe constipation

  • Brand name – Humco castor oil
  • CompositionCastor oil
  • Popularity level – 2
  • Castor oil is a vegetable oil extracted from seeds of Ricinus communis. It contains triglyceride ricinoleic acid which gets hydrolyzed in the intestines to form ricinoleic acid and glycerol. It acts by decreasing intestinal absorption of water and electrolytes,  thereby increasing secretion and aiding in bowel evacuation.
  • Dosage –  15-25 ml of the medicine should be taken in the morning.
  • Price – A bottle of 6oz of the oil costs$16.32

19. Epsom salt and Glauber’s salt: Cures occasional constipation

  • Brand name – Fair and pure
  • Composition – magnesium sulfate and sodium sulfate
  • Popularity level – 2
  • These salts are not absorbed in the intestine,  thus they retain water osmotically and distend the bowel by increasing peristalsis directly.
  • Dosage –  6-12g of the medicine should be dissolved in 150-200ml of water and taken on empty stomach.
  • Price – A bottle of 150 capsules cost £16.95

20. Sodium phosphate: Cures occasional constipation

  • Brand name – Oral Saline Laxative Ginger Lemon
  • Composition – Sodium Phosphate, Dibasic 2.7g in 15mL, Sodium Phosphate, Monobasic 7.2g in 15mL
  • Popularity level – 4
  • Dose dilute 3 -4 tablespoons with one glass (8 fl. oz.) cool water. Drink, then follow with at least one additional glass (8 fl. oz.) cool water. There is a significant loss of liquid when using this product. To prevent dehydration drink plenty of clear liquid after use.
  • Do not use if you have a previous kidney problem, congestive heart failure, impaired renal functions, decreased intervascular volume, dehydration, uncorrected electrolyte abnormalities in children under 5 years of age.

21. Softovac Powder: Cures chronic and acute constipation

  • Brand name – Softovac, Softovac SF
  • Composition –  Cassia Fistula, Haritaki, Licorice, Psyllium Husk and Senna
  • Popularity level – 6
  • This is an ayurvedic medicine that acts by increasing water content in the intestines and thus aiding in smooth bowel evacuation.
  • Dosage –  2-3 tablespoons with water, preferably before bed.
  • Price – A pack of 100g of the powder costs ₹138.

 

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