List of 21 Best Medicines for Gout – Composition, Dosage, Popularity & More (2019)

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List of 21 Best Medicines for Gout - Composition, Dosage, Popularity & More (2019)

Gout is a form of inflammatory arthritis characterized by acute intermittent episodes of synovitis presenting with joint swelling and pain; the episodes are referred to as acute gouty arthritis flares or attacks. The condition may progress to a chronic and persistent condition, with the development of tophi (solid deposits of monosodium urate [MSU] crystals in joints, cartilage, tendons, bursae, bone, and soft tissue), a condition called chronic tophaceous gout. There is no clear distinction between acute intermittent and chronic intermittent conditions, whereas the advanced stage of gout is characterized by more persistent joint manifestations and tophi (either clinically evident or hidden within the joint).

The annual incidence of gout in the US in people over 50 years of age is 1.6 per 1000 in men and 0.3 per 1000 in women. The incidence increases with age.

Gout is also known as gouty arthritis, the disease is caused by the formation of uric acid crystals in a joint (most often the big toe), triggering severe pain, redness, and tenderness. While certain factors, like genetics or kidney disorders, may predispose you to gout, diet, alcohol, and obesity can also contribute.

Treatment can include over-the-counter (OTC) and prescription drugs to alleviate pain and reduce uric acid levels. You can further minimize the frequency of attacks by losing weight, exercising regularly, and avoiding trigger foods.


List of Top 21 Medicines for Gout

  1. Allopurinol
  2. Colchicine
  3. Febuxostat
  4. Pegloticase
  5. Probenecid
  6. Probenecid and Colchicines
  7. Indomethacin
  8. Ibuprofen
  9. Naproxen
  10. Celecoxib
  11. Lesinurad
  12. Dexamethasone
  13. Hydrocortisone
  14. Methylprednisolone
  15. Triamcinolone
  16. Prednisone
  17. Lesinurad and allopurinol combination
  18. Benzbromarone
  19. Kaishore Guggulu
  20. Tart Cherry extract
  21. Uricel

Top 21 Medicines for Gout in India (Tablets, Syrups & More)

1. Allopurinol

  • Brand name – Allgout, Lodiric, Aloric, Myloric, Dynol, Algor
  • Composition Allopurinol
  • Popularity level – 9
  • Allopurinol is prescribed to treat gouty arthritis and prevent specific kidney stones by reducing high uric acid levels in the blood. Allopurinol reduces uric acid production.
  • Price – Aloric 100 mg is supplied in a pack of 10 tablets that cost ₹30.

2. Colchicine

  • Brand name – Colchicindon, Coljoy, Goutnil, Zycolchin
  • Composition – Colchicine
  • Popularity level – 8
  • Colchicine is an anti-gout agent, prescribed for gout or gouty arthritis. Colchicine reduces inflammation.
  • Price – Goutnil 0.5mg is supplied in a pack of 10 tablets that cost ₹32.

3. Febuxostat

  • Brand name – Fabulas, Feboxa, Febucip, Feburic, Goustat
  • Composition – Febuxostat
  • Popularity level – 7
  • Febuxostat is a xanthine oxidase (XO) inhibitor, prescribed for gout and hyperuricemia (high level of uric acid in the blood). Febuxostat reduces uric acid production.
  • Price – Fabulas 40mg is supplied in a pack of 10 tablets that cost ₹106.

4. Pegloticase

  • Brand name – Krystexxa
  • Composition – Pegloticase
  • Popularity level – 8
  • Pegloticase is a uric acid-specific enzyme (uricase), prescribed for chronic gout. Pegloticase breaks down uric acid.
  • Price – The cost for Krystexxa intravenous solution (8 mg/mL) is around $14,624 for supply of 1 milliliter(s).

5. Probenecid

  • Brand name – Bencid
  • Composition – Probenecid
  • Popularity level – 8
  • Probenecid is a uricosuric agent, prescribed for chronic gout and gouty arthritis. Probenecid helps the kidneys excrete uric acid from your body.
  • Price – A pack of 10 tablets cost ₹50.

6. Probenecid and Colchicines

  • Brand name – Rising Probenecid and Colchicine Tablets
  • Composition – Probenecid and Colchicine 500mg/0.5mg
  • Popularity level – 7
  • Probenecid and Colchicines contain a uricosuric agent and antigout, prescribed for gouty arthritis. The probenecid in this medicine helps to prevent gout attacks by removing extra uric acid from the body. The colchicine in this medicine also helps to prevent gout attacks.
  • Price – A pack of 100 tablets costs $65.54.

7. Indomethacin: Cures pain and reduced inflammation associated with gout

  • Brand name – Indocin 200 mg
  • Composition Indomethacin
  • Popularity level – 8
  • Indomethacin is a nonsteroidal anti-inflammatory drug (NSAID). Indomethacin is used to treat moderate to severe osteoarthritis, rheumatoid arthritis, gouty arthritis, or ankylosing spondylitis.
  • Price – A pack of 10 tablets cost ₹48.

8. Ibuprofen

  • Brand name -Motrin, Advil
  • CompositionIbuprofen
  • Popularity level – 6
  • Ibuprofen is a typical non-steroidal anti-inflammatory drug (NSAID) used for management of acute gout pain.
  • Price – The cost for Advil oral tablet 200 mg is around $12 for a supply of 24 tablets.

9. Naproxen

  • Brand name – Aleve
  • Composition Naproxen
  • Popularity level – 6
  • Acute attacks of gout are often treated with oral non-steroidal anti-inflammatory drugs (NSAIDs), which can ease pain and possibly reduce some of the inflammation.
  • Price – A bottle pack of 50 caplets costs $10.84.

10. Celecoxib

  • Brand name – Celebrex
  • Composition – Celecoxib
  • Popularity level – 7
  • Is a non-steroidal anti-inflammatory drug, often referred to simply as an NSAID. NSAIDs block swelling, pain, and fever. Celebrex works by stopping the production of COX-2, a natural substance in the body that causes pain and inflammation. Celebrex is an NSAID and a COX-2 inhibitor
  • Cox-2 inhibitors are a newer class of NSAID, which work to reduce inflammation but do not carry the same risk of gastrointestinal side effects.
  • Price – The cost for Celebrex oral capsule 50 mg is around $224 for a supply of 60 capsules.

11. Lesinurad

  • Brand name – Zurampic 200mg
  • Composition – Lesinurad
  • Popularity level – 6
  • Lesinurad in combination with a xanthine oxidase inhibitor provides an effective mode of therapy in the management of hyperuricemia associated with gout. Lesinurad is a selective uric acid transporter 1 (URAT1) inhibitor. URAT1 is responsible for the majority of uric acid absorption from kidneys to the circulation. Lesinurad helps your body get rid of uric acid when you pee.
  • Price – The cost for Zurampic oral tablet 200 mg is around $396 for a supply of 30 tablets.

12. Dexamethasone

  • Brand name – Dexamax
  • CompositionDexamethasone
  • Popularity level – 9
  • Dexamethasone is a steroid that prevents the release of substances in the body that cause inflammation.
  • Price – A bottle pack of 100 tablets cost ₹64.

13. Hydrocortisone

  • Brand name – Cortef
  • Composition – Hydrocortisone
  • Popularity level – 7
  • Corticosteroids decrease the pain, swelling, redness, and warmth (inflammation) of gout.
  • Corticosteroids usually provide rapid relief from gout symptoms. Because of their potential side effects, if used for a long time, corticosteroids are usually prescribed only for a short time.
  • Price – The cost for Cortef oral tablet 5 mg is around $60 for a supply of 50 tablets.

14. Methylprednisolone

  • Brand name – Medrol 4mg
  • CompositionMethylprednisolone
  • Medrol decreases your immune system’s response to various diseases to reduce symptoms such as swelling, pain, and allergic-type reactions. This medication is a corticosteroid hormone.
  • Dosage – 4mg once or twice in a day with a meal.
  • Price – A pack of 10 tablets cost ₹50.

15. Triamcinolone

  • Brand name – Kenalog
  • Composition – Triamcinolone
  • Popularity level – 4
  • Triamcinolone acetonide is a synthetic corticosteroid used topically to treat various joint conditions.
  • Price – The price range for Kenalog In Orabase 0.1 % is $5.50 – $9.80 per pill or unit.

16. Prednisone

  • Brand name – Delsone 20mg
  • Composition – Prednisone
  • Popularity level – 6
  • Prednisone is also a steroidal drug. A short course of oral steroids is used (prednisone) for treatment of acute gout when nonsteroidal anti-inflammatory drugs (NSAIDs) are contraindicated. Steroids are also a reasonable choice as first-line treatment.
  • Dosage –  30-40 mg/d for 5 days
  • Price – A pack of 10 tablets cost ₹17.

17. Lesinurad and Allopurinol Combination

  • Brand name – Duzallo
  • Composition – Lesinurad 200 mg plus Allopurinol 300 mg
  • This combination medication is used to lower uric acid when allopurinol alone has not worked well enough.
  • Dosage –  It should be taken in the morning with food and water, and patients should be advised to stay well hydrated when taking the medication.
  • Price – The cost for Duzallo oral tablet (200 mg-200 mg) is around $396 for a supply of 30 tablets.

18. Benzbromarone

  • Brand name – Nogout 100mg
  • Composition – Benzbromarone
  • Popularity level – 6
  • Benzbromarone (INN) is a uricosuric agent and non-competitive inhibitor of xanthine oxidase used in the treatment of gout, especially when allopurinol, a first-line treatment, fails or produces intolerable adverse effects.
  • Price – A bottle pack of 100 tablets costs $63.

19. Kaishore Guggulu

  • Brand name: Patanjali Kaishore Guggulu
  • Composition – Giloy or Guduchi (Tinospora cordifolia), Amla (Emblica Officinalis), Bibhitaki (Terminalia bellirica), Haritaki (Terminalia chebula), Shuddha Guggulu (Commiphora Mukul), Shunthi (Zingiber Officinale), Black pepper (Piper Nigrum), Pipali (Long Pepper), Vidanga (Embelia Ribes), Nisoth (Operculina Turpethum) and Danti Mool (Baliospermum Montanum)
  • Popularity level – 2
  • Kaishore Guggulu (also called pathyadi Guggulu) is an ayurvedic guggul formulation used for raised uric acid, mild to severe attacks of gouty arthritis, inflammatory diseases, wounds, abdominal diseases, constipation, indigestion, diabetic carbuncles etc.
  • It is a drug of choice in gout. Overproduction of uric acid in the body and decrease in excretion of uric acid through the kidneys are the main cause of gout or raised uric acid. Kaishore Guggulu works well in both conditions.  It corrects the metabolism and checks on uric acid production.
  • Price – A bottle pack of 80 tablets cost ₹60.

20. Tart Cherry extract

  • Brand name – Goutritis
  • Composition – Tart Cherry extract
  • Popularity level – 2
  • This all-natural herbal dietary supplement provides relief from the swelling and pain without the side effects commonly associated with prescription drugs such as drug-induced liver disease.
  • Tart cherry is the active ingredient in Goutritis. This has antioxidants which help reduce inflammation associated with gout. Moreover, tart cherry has properties that may lower uric acid levels to address not just the symptoms but also the root cause of gout. It inhibits the activity of Xanthine oxidase, the enzyme which causes the production of uric acid.
  • Dosage – Three capsules of Goutritis, taken daily before breakfast, will help the patient manage his gout.
  • Price – Goutritis is available in bottles of 90 capsules (₹900) and blister packs of 10 capsules (₹100).

21. Uricel

  • Brand name – Uricel
  • Composition – Turmeric, Celery Seed Extract, Yucca Root, Devil’s Claw, Tart Cherry, and Chanca Piedra
  • Popularity level – 3
  • Uricel is a powerful uric acid support supplement that helps flush your body naturally. It helps soothe discomfort while supporting healthy uric acid levels in order to support long-term mobility.
  • 5 Natural Anti-Inflammatory Ingredients: Turmeric, Celery Seed Extract, Yucca Root, Devil’s Claw & Tart Cherry: All are Powerful, natural anti-inflammatories and antioxidants that are gentle on the stomach.
  • Chanca Piedra: Kicks the digestive system into gear so it can flush the excess.
  • Price – This medicine comes in the form of a syrup. A 5oz bottle pack costs $ 45.46

 

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