Betamethasone: Uses, Dosage, Side Effects, Precautions, Price & More

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Betamethasone: Uses, Dosage, Side Effects, Precautions & More

What is Betamethasone?

Betamethasone is a steroid medication. Betamethasone is a corticosteroid medication which reduces the chemicals in the body that causes inflammation. It also reduce immune responses in the body

Check out Hindi translation of this article - Betamethasone in Hindi
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Uses of Betamethasone

It is used for the treatment of hormone-related disease, such as:

  • Thyroid Problems
  • Arthritis
  • Allergic Problems
  • Asthama
  • Eye Diseases
  • Respiratory Diseases
  • Skin Diseases
  • Blood Disorders
  • Cancer
  • Gastrointestinal (Stomach) Diseases
  • Kidney Diseases
  • Multiple Sclerosis

Betamethasone Price in India

Specifics Betamethasone Price
Betamethasone, Neomycin,Tolnaftate Tube of 10 gm Cream Rs 35
Betamethasone, Clotrimazole Tube of 15 gm Ointment Rs 60

How to Take Betamethasone?

Betamethasone usually comes in the form of

  • Tablets
  • Syrups
  • Topical Cream
  • Injectable Forms

Every possible formulation might not be listed here.

  • Betamethasone tablets are usually taken by mouth with a glass of water as directed by your doctor, usually once daily with or without food
  • For best results, Betamethasone must be taken at evenly spaced times
  • Betamethasone syrup (contains 0.6 mg betamethasone in each 5 mL)
  • Shake the suspension liquid well before each use to mix the medication evenly
  • Use a measuring cup to consume the correct dosage of medicine
  • Bethamethasone eye/ear/nose-drops (Betamethasone Sodium Phosphate 0.1% w/v)
  • Dropper is used to put the medicine in the affected eye/ear/nose as directed by the physician
  • The usage of betamethasone must be continued until the prescribed dosage is finished, even if your symptoms disappear
  • Betamethasone injectable suspension is given by a healthcare provider in a clinical setting
  • You should not attempt to administer this drug yourself
  • It is always advised for the user to read the Patient Information Leaflet provided by the pharmacist and further queries must be solved with your doctor or pharmacist

Common Dosage For Betamethasone?

The drug dosage and form is decided by the physician based upon:

  • age and body weight of the patient
  • health status/medical condition of the patient
  • disease severity
  • reaction to the first dose
  • history of allergy/drug reactions

After a desirable response is achieved, the doctor determines the maintenance dose by reducing the initial dose in small decrements at regular intervals until the minimum possible dose which will sustain a satisfactory clinical response is achieved.

Dosage for Betamethasone syrup

The initial dose of Betamethasone Syrup may vary from 0.6 mg to 7.2 mg/day depending on the medical condition being treated.

Dosage schedule for drops

For eyes – Adults, Elderly and Children:

  • Initially 1-2 drops into the affected eye(s) every 2 hours
  • The dose should be decreased once the medical condition is under control

For ears – Adults, Elderly and Children:

  • Initially 2-3 drops into the affected ear(s) every 3-4 hours
  • The dose should be decreased once the medical condition is under control

For nose – Adults, Elderly and Children:

  • 2-3 drops into each nostril 2 times daily as needed

Usual adult dose for tablets – (Anti-inflammatory action) – 0.6 to 7.2 mg/day orally

  • Betamethasone topical cream is usually applied over the affected area 1 or 2 times daily
Also read: Candid B Dosage | Calcirol Dosage | Bifilac Dosage

Precautions – When To Avoid Betamethasone?

  • If you have high blood pressure.
  • If you have a history of heart attack, or any other heart disease.
  • If you have any liver / kidney disease.
  • If you have or if you have a family history of diabetes or glaucoma.
  • If you have thyroid problems, osteoporosis (especially in postmenopausal women), epilepsy (seizures), myasthenia gravis(a disease causing muscle weakness), stomach ulcers or diseases.
  • If you have a history of mental health diseases.
  • If you are pregnant or a nursing mother
  • If you have any infectious disease, or if you have a history of tuberculosis.
  • If you have a history of blood clot.
  • If you recently took a vaccination or planning to take one.
  • If you have a history of allergy after taking steroid medication.

Side-effects of Betamethasone?

The possible side-effects include –

  • Feeling of excitement or depression
  • Emotional instability
  • Increased blood pressure
  • Increased heart beats
  • Petechaie or blood spots under the skin
  • Delayed healing of wounds
  • Excessive hair growth
  • Acne, broken or raw skin
  • Darkening of the skin
  • Increased bloating in abdomen and increased abdominal fat
  • Blurred vision
  • Bulging in eyes
  • Weakness in bones
  • Heart attacks
  • Seizures
  • Reduced carbohydrate and sugar tolerance
  • Reduced resistance to infectious diseases
  • Diabetes, weight gain, insomnia
  • Dizziness, drowsiness
  • Fainting, headache
  • Increased sweating
  • Altered sperm count
  • Joint pains
  • Indigestion
  • Muscle weakness / muscle disease
  • Nervousness
  • Numbness and tingling
  • Psychotic disorders
  • Partial paralysis
  • Stretchmarks
  • Spinning sensation

Reported Allergic Reactions?

Possible allergic reactions reported are:

  • Rashes
  • Difficulty breathing or swallowing
  • Swelling
  • Red, itchy bumps on skin 

Effect on organs –

  • Betamethasone can lead to enlarged heart and liver
  • It can cause elevation of levels of liver enzymes and increase fluid in the lungs

Drug Interactions To Be Careful About

  • All the possible drug interactions might not be listed here. You must always inform the physician of all the drugs/products you use.
  • Drug interactions with the following medications have been noted –
    • Aminoglutethimide
    • Amphotericin B injection and potassium-depleting agents
    • Antibiotics like azithromycin
    • Anticholinesterases – anticholinesterase agents should be stopped minimum 24 hours before starting corticosteroid therapy.
    • Anticoagulants, oral (blood thinners)
    • Anti-diabetics: Betamethasone can raise glucose concentrations in blood, therefore, dosage adjustments of antidiabetic drugs is necessary.
    • Anti-tubercular drugs like isoniazid
    • Cholestyramine
    • Cyclosporine – Convulsions have been reported if both medicines are used together.
    • Digitalis glycosides
    • Estrogens, including oral contraceptives.
    • Hepatic Enzyme Inducers (e.g., barbiturates, phenytoin, carbamazepine, rifampin): these drugs may require that the dosage of the Betamethasone to be increased.
    • Ketoconazole, anti-fungal drugs: Ketoconazole has been reported to increase the risk of Betamethasone side effects.
    • Nonsteroidal anti-inflammatory agents (pain killers): increases the risk of gastrointestinal side effects.
    • Skin tests: Corticosteroids may suppress reactions to skin tests.
    • Vaccines: Routine administration of vaccines should be deferred until corticosteroid therapy is discontinued if possible.
  • You must also inform about the herbal products that you are consuming
  • You must not modify the drug regimen without your doctor’s approval

Shows Effects / Results In:

The time taken for Betamethasone to show its effect depends upon the form of medicine being consumed and its intended use.

Pro Tips When Taking Betamethasone –

  • Never discontinue or initiate or alter the drug dose unless advised by your physician.
  • The chances of catching an infectious diseases becomes higher while you are on Betamethasone (corticosteroid) therapy. Always be in regular contact with your physician. 

History

Betamethasone was accepted for medical use in the US in 1961.

Also read side effects ofAscoril LS Cough Syrup | Azithral 500 | Becadexamine Capsule

FAQ

Is Betamethasone Addictive?

No

Can I have Betamethasone with alcohol?

No.

Please inform your physician before consuming alcohol.

 Any particular food item to be avoided?

No.

Can I have Betamethasone When Pregnant?

  • Always inform your doctor if you are pregnant or plan to become pregnant
  • Betamethasone should be used in pregnant females only after assessing the potential benefit risk ration to the mother and foetus
  • The baby born to a mother on Betamethasone therapy should be carefully observed for signs of hypoadrenalism

Can I have Betamethasone when feeding a baby?

  • Always inform your doctor if you are breast-feeding your child
  • Betamethasone should be avoided in breastfeeding women as it can appear in human milk and can inhibit growth and cause other untoward effects

Can I drive after taking Betamethasone?

Betamethasone can cause dizziness, drowsiness, state of depression and other side effects when administered systemically. Therefore, driving should be avoided.

What happens if…


I overdose on Betamethasone?

  • An overdose of Betamethasone can cause poisoning or severe side-effects
  • If you have taken an over-dose, it is advisable to contact your consulting physician immediately

I eat expired Betamethasone?

  • It is very unlikely for a single dose of expired Betamethasone to produce an adverse event
  • However, please consult your physician if you feel unwell or sick after consuming an expired medicine
  • An expired drug might not be as potent in treating your condition. It is advisable to refrain from using expired drug

I miss a dose of Betamethasone?

  • Always consume the missed dose as soon as you remember it
  • But, if it’s already time to take the second dose after that – do not take double dose

Storage Requirements for Betamethasone

  • Betamethasone must always be stored away from direct light & heat, in a cool and dry environment
  • The room temperature must be between 15-30° C

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