Bisoprolol: Uses, Dosage, Price, Side Effects, Precautions & More

What is Bisoprolol?

Bisoprolol (ZEBETA) is a highly selective 1 receptor antagonist that does not have intrinsic sympathomimetic or membrane-stabilizing activity. Bisoprolol is a type of antihypertensive used to treat hypertension (high blood pressure). Bisoprolol has shown to reduce the mortality rate in large cohorts of patients with stable chronic heart failure regardless of severity.

Manufactured By – Shrrishti Health Care Products Pvt Ltd

Buy & Get Minimum 20% Discount: 1Mg | Medlife

Uses of Bisoprolol

  • Bisoprolol can be considered a standard treatment option when selecting a blocker for use in combination with ACE inhibitors and diuretics in patients with stable, moderate to severe chronic heart failure and in treating hypertension.
  • It has also been used to treat arrhythmias and ischemic heart disease.
Also Read: Melatonin Uses | Methadone Uses

How does Bisoprolol work?

Bisoprolol is a type of medicine called a beta blocker. Like other beta blockers, Bisoprolol works by changing the way your body responds to some nerve impulses, especially in the heart. It slows down your heart rate and makes it easier for your heart to pump blood around your body.

How to take Bisoprolol?

  • Bisoprolol only comes as a tablet you take by mouth.
  • It’s usual to take Bisoprolol once a day in the morning.
  • Bisoprolol doesn’t usually upset your tummy so you can take it with or without food.
  • Swallow the tablets whole with a drink of water.
  • Some brands have a score line to help you break the tablet to make it easier to swallow.

Bisoprolol Price In India

Specifics Bisoprolol Price
2.5 mg Strip of 10 Tablets Rs 18.00
5 mg Strip of 10 Tablets Rs 25.99
10 mg Strip of 10 Tablets Rs 48.82
Other medicine's Price: Dulcolax Price | Enalapril Price

Common Dosage for Bisoprolol

  • In the case of hypertension, 2.5-5 mg orally once per day. It can be increased to 20mg per day in serious cases.
  • 1.25 mg orally once per day is given to heart failure patients. It is increased slowly to 10mg max per day.

When to avoid Bisoprolol?

  • When Bisoprolol is taken with antidepressants, nitrates (for chest pain), baclofen (a muscle relaxant), medicines for an enlarged prostate gland like tamsulosin, or Parkinson’s disease medicines, such as co-careldopa and levodopa, it can lower the blood pressure.
  • Combination of NSAIDs and Bisoprolol can stop Bisoprolol from working efficiently.
  • Heart rhythm drugs (sotalol, amiodarone, digoxin, moricizine) may cause a lower heart rate or more side effects.
  • Bisoprolol might affect how lidocaine is cleared from your body. This can cause lidocaine toxicity.
  • Using mefloquine with Bisoprolol can cause heart rhythm abnormalities and your heart may stop working.
  • Using stimulants can make both Bisoprolol and stimulant to not work.

There are other drug interactions not mentioned here. Consult your doctor if you are taking other medications to know the effect of combining it with Bisoprolol.

Precautions while taking Bisoprolol

  • Tell your doctor if you are allergic to Bisoprolol or to any of the ingredients present in it.
  • Tell your doctor if you have any heart or kidney or liver problem or any other health issue.
  • This drug may make you dizzy. Alcohol can make you dizzier.

Side Effects of Bisoprolol

Some of the commonly reported side effects of Bisoprolol are:

  • Dizziness
  • Bradycardia
  • Hypotension
  • Fatigue
  • Constipation

Effects on organs?

  • Cardiovascular reactions- Bradycardia, chest pain, heart failure aggravation, hypotension, cold extremities, peripheral edema, ischemia, left cardiac failure, palpitation, vein disorder.
  • Nervous system reactions- Dizziness, headache, cerebrovascular disorder, syncope.
  • Respiratory reactions- Dyspnea, pneumonia, bronchitis, coughing, exertional dyspnea, upper respiratory tract infection, respiratory distress.
  • Skin reactions- pruritus
  • Gastrointestinal reactions- Nausea, vomiting, diarrhea, constipation, dyspepsia, abdominal pain, gastritis, dry mouth.

Storage Requirements for Bisoprolol

  • Keep Bisoprolol in a dry, airtight container.
  • Keep it away from direct heat or moisture.
  • Keep it out of reach of the children.

Pro Tips When Taking Bisoprolol

  • Continue to take Bisoprolol even if you feel well.
  • Bisoprolol is taken once a day. Try to take tablets at the same time each day.
  • Your very first dose of Bisoprolol may make you feel dizzy, so take it at bedtime. After that, if you don’t feel dizzy, it’s best to take it in the morning.
  • Seek medical advice immediately if shortness of breath develops.
  • Generic Bisoprolol is available.


Is Bisoprolol addictive?

No, Bisoprolol is not addictive.

Can I have Bisoprolol with alcohol?


Any particular food item to be avoided?

Avoid salt and potassium-rich foods.

Can I have Bisoprolol when pregnant?

No, do not have Bisoprolol when pregnant.

Can I have Bisoprolol while feeding a baby?


Can I drive after taking Bisoprolol?


What happens if I overdose on Bisoprolol?

Overdose of Bisoprolol can slow down your heart rate and make it difficult to breathe. It can also cause dizziness and trembling.

What happens if I eat expired Bisoprolol?

Expired medicines may have lost potency and will not be as effective as earlier. Sometimes it can be harmful to the body.

What happens if I miss a dose of Bisoprolol?

Take the missed dose as soon as you remember it. Skip the missed dose, if it’s time for the next dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

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