Bren: Uses, Dosage, Side Effects, Price, Composition, Precautions & More

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Bren: Uses, Dosage, Side Effects , Price, Composition, Precautions & More

What is Bren?

  • Bren acts as a nonsteroidal anti-inflammatory drug (NSAID).
  • NSAIDs, help reduce fever, decrease pain, and prevent clotting of blood and also reduce inflammation in the body when used in higher doses.
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Uses of Bren

Bren is prescribed for:

  • Mild to moderate pain from headache
  • Toothache
  • Menstrual cramps
  • Muscle ache
  • Common cold
  • Backache
  • Inflammation of the joints by arthritis

How does Bren work?

Bren medicine works by reducing the activity of a chemical in the body, prostaglandin that causes pain and swelling.

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Bren Price In India

Specifics Bren Price
Bren 200mg Strip of 15 Tablets Rs. 6.14
Bren 400mg Strip of 15 Tablets Rs. 10.59
Bren 600mg Strip of 15 Tablets Rs. 14.86
Bren 100mg/5ml Suspension Rs. 8.52
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How to take Bren?

  • Bren is administered orally in the form of capsule and tablet, with or without food.
  • To prevent stomach upset, take it with food or milk.

Common dosage of Bren

  • Dosage for painful swelling and stiffness of the joints, in adults is 1200-3200 mg given 3 times daily.
  • Dosage for painful swelling and stiffness of the joints in children is 20 mg to 30 mg per kg. This is given in 3-4 parts per day.
  • Dosage for painful menstrual periods is 400 mg every 4 hours.
  • Recommended dosage for fever is 200-400 mg every 4 to 6 hours. Maximum should not exceed 1200 mg per day.

When to avoid Bren & Precautions to take?

  • Avoid using Bren if you are allergic to NSAIDs or any other inactive ingredients present along with it.
  • Bren may cause stomach bleeding and the risk is increased if the patient takes tobacco or drinks alcohol or is an elderly patient.
  • This medicine should not be used in case of chickenpox due to increased risk of infection.
  • Bren may increase your sensitivity to sunlight and make you prone to sunburn.
  • Prolonged use of Bren increases the risk of heart attack, stroke, ulcers, and bleeding of the stomach and intestines.
  • Caution is advised in patients with kidney disease, high blood pressure, fluid retention or risk of heart failure or with a history of stomach ulcer or bleeding.

Side Effects of Bren

  • Abdominal pain
  • Bleeding in the stomach/intestines
  • Constipation
  • Dark sticky stools with blood
  • Diarrhoea
  • Fatigue
  • Headache
  • Nausea
  • Vomiting
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Effect on organs?

  • Gastrointestinal reactions- Nausea, epigastric pain, heartburn, diarrhoea, abdominal distress, vomiting, blood in stools, indigestion, constipation, abdominal cramps or pain, bloating and flatulence.
  • Central nervous system reactions- Dizziness, headache and nervousness.
  • Dermatological reactions- Rash and itching.
  • Ear problems- Ringing in the ear.
  • Metabolic reactions- Decreased appetite.
  • Cardiovascular reactions- Edema and fluid retention.

Reported allergic reactions?

Allergic reactions may include:

  • Rashes
  • Trouble breathing
  • Swelling of face, throat or hands
  • Angioedema

Drug interactions to be careful about?

  • Angiotensin-converting enzyme (ACE) inhibitors- Bren reduces the blood pressure lowering effect of ACE inhibitors.
  • Diuretics- Bren interacts with diuretics, which increases the production of urine and can lead to an increased risk of kidney damage.
  • Aspirin- Co-administration of Bren along with aspirin increases the risk of stomach and intestine related health issues.
  • Mifepristone- Bren may interact with mifepristone and reduce its effects.
  • Corticosteroids- The combined usage of Bren with corticosteroids can lead to an increased risk of gastrointestinal bleeding.
  • Cardiac glycosides- Co-administration of these two medicines may worsen the cardiac failure condition and reduce the functioning of the kidneys.
  • Sulfonylureas- Bren interacts with sulfonylureas and may increase the effect of sulfonylureas.
  • Anticoagulants- Concomitant use of Bren with anticoagulants (warfarin) can lead to an increased risk of gastrointestinal bleeding.
  • Methotrexate- Bren when taken along with this medicine may increase the harmful effects of methotrexate.

Shows effects

  • Bren is a pain killer and relieves pain by blocking production of prostaglandin, which is released during pain.
  • It may sow its effects within an hour or two after its administration.

Storage Requirements for Bren

  • Keep it in an air-tight container.
  • Store it at temperature between 20 and 25.
  • Keep it away from direct light or moisture.
  • Keep it out of reach of children.

Pro Tips when taking Bren

  • Bren should be taken with food or milk to prevent upset stomach.
  • Long term use of Bren may lead to serious complications such as stomach bleeding and kidney problems.
  • Do not take antacids within two hours of taking Bren.
  • Avoid consuming alcohol while taking Bren.

FAQs – Things to Know About Bren

Is Bren addictive?

No

Can I have Bren with alcohol?

No

Any particular food item to be avoided?

Avoid garlic due to the risk of bleeding.

Can I have Bren when pregnant?

No

Can I have Bren when feeding a baby?

Yes; only if benefit outweigh the risks.

Can I drive after taking Bren?

No

What happens if I overdose on Bren?

Overdose of Bren may cause abdominal pain, blood in the urine, convulsions, slow heart and breathing rate.

What happens if I eat expired Bren?

Expired Bren may become ineffective in treating your prescribed conditions, thus to be on the safe side, it is important not to use expired drug.

What happens if I miss a dose of Bren?

If you miss a dose of Bren, skip it and continue with your normal schedule. Do not double dose for a missed one.

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