Bupropion: Uses, Dosage, Price, Side Effects, Precautions & More

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What is Bupropion?

Bupropion is sold under the brand name Wellbutrin and Zyban. It is an effective anti-depressant drug. Bupropion is used as a common medication as a smoking cessation aid.
Manufactured By – Sun Pharmaceutical Industries Ltd

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Uses of Bupropion

  • Bupropion is used to treat sleeplessness and fatigue.
  • It is also used to treat cravings and withdrawal symptoms of nicotine.
  • Bupropion is effectively used to treat clinical depression.
Also Read: Baclofen Uses | Cialis Uses

How Does Bupropion Work?

  • Nerves may recycle neurotransmitters which are called as reuptake process.
  • Bupropion inhibits the reuptake of these neurotransmitters (dopamine, serotonin, and norepinephrine)
  • This results in more neurotransmitter to transmit messages to the other nerves.

How to Take Bupropion?

  • Swallow the tablet wholly. Do not crush, chew or break it.
  • You can take Bupropion with or without food.
  • Bupropion is usually taken two times per day with 4 to 6 hours in between which is morning and mid-afternoon.

Bupropion Price in India

Specifics Bupropion Price
Bupropion (Volume of 10) Rs 137.50

Common Dosage for Bupropion

  • The dosage is different for according to different conditions. So it is safe to consult the doctor before taking the dosage.
  • For depression, the initial dose is about 100mg per day twice a day. The maximum dose is about 450mg per day which can be taken four times.
  • For seasonal affective disorder, the dose is from 150mg per day which can be increased up to 300mg per day.
  • In the treatment of smoking cessation which period is from 7 to 12 weeks, the dosage is between 150mg to 300mg taken twice a day.
Also read about other medicine Dosage: Januvia Dosage

Precautions – When to Avoid Bupropion?

While taking the Bupropion you should follow the steps as,

  • Don’t delay or miss scheduled meal or snack
  • Don’t take Bupropion along with other certain medications.
  • Avoid consuming alcohol for initial days while taking Bupropion.

Side-Effects of Bupropion

Some common side effects of Bupropion are:

  • Nausea
  • Vomiting
  • Dry mouth
  • Dizziness
  • Stomach pain
  • Headache
  • Ringing in the ears
  • Sore throat
  • Muscle pain
  • Increased level of urinating and swearing
  • Mild itching and rashes
  • Loss of appetite
  • Weight gain or loss

Effects of Bupropion on Organs

There are very few evidences to report that Bupropion may cause jaundice and acute liver damage. As this drug is removed from the body by the disease it may also cause chronic kidney disease.


Drug Interactions to be Careful About

Drugs like carbamazepine, phenobarbital, and phenytoin can decrease the effect of Bupropion. Levodopa and amantadine interaction with this drug can cause CNS toxicity. With MAO inhibitors, this drug can cause hypertension.


Effects/Results after Consuming Bupropion

Bupropion will show its effect within 1 to 2 hours and it may take up to 14 hours to get out if the system. But you should follow this medication for 4 to 5 weeks for full recovery.


Storage Requirements about Bupropion

Bupropion can be stored in a closed container at room temperature away from heat, moisture and direct light.


Pro Tips When Taking Bupropion

Bupropion should be taken in prescribed dosage and must only increase the dosage when the physician prescribed it. Do not abruptly stop taking this drug as it may cause negative effects on body. Avoid alcohol and certain recommended foods while taking Bupropion.


FAQs – Things to Know About Bupropion

Is Bupropion addictive?

No. But it can cause adverse effects when it is abruptly stopped.

Can I have Bupropion with alcohol?

No. Having Bupropion with alcohol will cause seizures, hallucinations, and mood and behaviour changes.

Any particular food item to be avoided?

Avoid food items which are recommended by your doctor.

Can I have Bupropion when pregnant?

No Bupropion is recommended during pregnancy as it heart defects in baby. Although you can take advise from your doctor.

Can I have Bupropion when feeding a baby?

Taking Bupropion while breastfeeding can cause seizures in infants as it may pass through the breast milk.

Can I drive after taking Bupropion?

You should avoid driving if you feel drowsy as it may sometimes increase your blood pressure.

What happens if I overdose on Bupropion?

It would cause seizures, rapid heartbeat, hallucination and aggressive behaviour.

What happens if I eat expired Bupropion?

It will not be effective but take advice from your doctor immediately.

What happens if I miss a dose of Bupropion?

If you miss a dose of Bupropion take it as soon as you remembered it within 12 hours. If you don’t, just go back your regular dosage.

When Was Bupropion Made?

Bupropion was made in the year 1969 by Nariman Mehta.

Also Read: Acetaminophen | Albuterol | Amitriptyline

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