Ciplox TZ Tablet: Uses, Dosage, Side Effects, Price, Composition & 20 FAQs

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Ciplox TZ Tablet: Uses, Dosage, Side Effects, Price, Composition & 20 FAQs

1What is Ciplox TZ?

It is a medicine which is used to prevent or treat conditions and infections like amoebiasis, vaginal and urinary tract infections, infectious diarrhoea. Seizures, tremors and exacerbation of myasthenia gravis are the major side effects seen at high repetitive doses. It should be totally avoided in case of liver, kidney diseases or blood disorders.

Ciplox TZ Composition: Ciprofloxacin 500mg + Tinidazole 600mg
Manufactured By: Cipla
Prescription: Required as it belongs to Schedule ‘H’ but also available as OTC
Form: Tablet, drops and oitments.
Price: Rs. 117.19 for 10 tablets.
Expiry/Shelf Life:  24 months from the date of manufacturing
Type of Drug: 
Antibiotic + Antidiarrhoeal

Also read in Hindi about Ciplox TZ


2Uses of Ciplox TZ

Ciplox TZ is used to prevent or treat following conditions:

  • Gonorrhea: Used to treat gonorrheal infection of vagina caused mostly by transfer of bacterial infection during unprotected sex.
  • Pneumonia: Used to treat cases of Pneumonia as it is caused by bacteria.
  • Diarrhoea: Used to treat diarrhoea that is suspected to be caused by bacterial infection.
  • Dysentery: Used to treat and manage diarrhoea with blood and stomach cramps.
  • Parasitic infections: Also useful against infections caused by parasites like cases of amoebiasis and giardiasis.
  • Dental Infections: Used to treat dental infections as most of the dental infections are known to be caused by anaerobic bacteria against which Ciplox TZ is most potent.
  • Abdominal Infections: Used to treat intra abdominal infections.
  • Vaginal Infections: Used to treat and manage vaginal infections.
  • Postoperative Infections: Used in cases of postoperative management to prevent or cure anaerobic infections.
  • UTIs: used to treat and manage Urinary tract infections.
  • Skin and Soft Tissue Infections: Used to treat infections of skin and soft tissue which are expected to be caused by bacteria.
  • Sinusitis: Used to treat inflammation and infection of sinus known to be caused by bacteria.
  • Others: Used to treat Various cases of Lung Abscess.
Also Read: Cinnarizine Uses | Cipcal 500 Uses

3How does Ciplox TZ work?

  • Ciplox TZ contains Ciprofloxacin and Tinidazole as its main active ingredient.
  • Ciprofloxacin belongs to the Ouinolone group of drugs and works by inhibiting the DNA synthesis of bacterial cells and prevents the multiplication of bacterial cells and thereby killing them.
  • Tinidazole belongs to the Nitroimidazole group of drugs which shows antiparasitic activity
  • Tinidazole works by breaking the DNA strands and thereby damaging the DNA of microbes and eradicating the infection.
  • Ciplox TZ, therefore, exhibits both bactericidal and antiparasitic activity.

4How to take Ciplox TZ?

  • Ciplox TZ is usually available in the form of tablets, drops, and ointments.
  • Ciplox TZ Tablet is taken by mouth with a glass of water preferably with or after meals as food helps to prevent any potential gastric irritation the drug might cause when taken empty stomach.
  • Ciplox TZ Tablet should never be chewed or crushed. It should be swallowed as a whole.
  • Ciplox TZ should be consumed in infections which are known to be bacteria and parasites only to prevent the development of resistance against the antibiotic. Culture tests can be performed toruleout the possibility of bacterial infection.
  • Ciplox TZ Tablet should be taken with an equal time interval of atleast 8-10 hours between two doses.
  • It is advisable to go through the pack insert properly before consuming the drug to have a better understanding of the drug.

5Common Dosage for Ciplox TZ

  • Ciplox TZ dosage can be decided by the doctor for every individual as per Age, Weight, Mental status, Allergic history and, the Health status of the patient.
  • The common Adult dose of Ciplox TZ Tablet is a single tablet twice a day with an interval of at least 8-10 hours between two doses.
  • It is not recommended to be administered to children without pediatric consultation
  • Dose alteration should be avoided without proper medical consultation.

Q. What happens if I overdose on Ciplox TZ?

Overdose of Ciplox TZ can cause undesirable effects and can also lead to complications in a few cases.
Therefore, strictly adhere to the prescribed dose and seek medical help immediately in case of any symptoms of overdose.

Q. What happens if I miss a dose of Ciplox TZ?

The dose prescribed by the doctor should never be missed and if missed, it should be consumed always as soon as you remember it. But, avoid taking a double dose if it’s already time for the second dose after that as it may lead to an overdose of the drug. A gap of atleast 8-10 hours should be there between two doses.

Q. What happens if I eat expired Ciplox TZ?

Consuming expired Ciplox TZ tablet might not exhibit desirable effects or any side effects. However, one should abstain from consuming the expired drug.

Q. Onset time of Ciplox TZ and till when does the effect of Ciplox TZ stays?

The time taken by the drug to show its effect depends upon the condition being treated.

Time is taken by the drug to show the desired effects may vary with every individual patient.

Also read about other medicine dosages: Ciprofloxacin | Citralka | Clavam 625

6When to Avoid Ciplox TZ?

Do not Consume Ciplox TZ if:

  • Allergy: In cases of known allergy to Ciplox TZ or any other drug belonging to the class of quinolones and Nitroimidazole like levofloxacin, ofloxacin, etc.
  • Gastric bleeding: In cases of patients with a history of gastric ulcer, bleeding or perforations as it can cause swelling and bleeding of stomach, colon or anus.
  • Epilepsy: patients with epilepsy should avoid the drug as Ciplox TZ can precipitate seizures.
  • Myasthenia gravis: Should avoid the drug in cases of Myasthenia gravis.
  • Liver/ Kidney impairment: In cases of patients with liver disease and kidney disease or impairment. Patients on dialysis should also avoid this drug unless advised by the doctor.
Also read side effects of other medicines: Clopilet | Cobadex Czs | Clindamycin Phosphate Gel

7Precautions While Taking Ciplox TZ:

  • Concomitant medication: Patients taking tizanidine should avoid the concomitant use of Ciplox TZ.
  • Liver/ Kidney diseases: Dose alteration may be required by the physician in patients with kidney or liver impairments.
  • Dose alteration: Dose alteration without proper medical consultation should be avoided.

Warnings When Taking Ciplox TZ

  • Prolonged use unless stated by the doctor should be avoided.
  • There should be the equally spaced time interval between two doses.
  • Consume plenty of fluids to counteract the potential undesirable effects of the drug.
  • Always consume the tablet with or after meals to prevent any gastric irritation.
  • Always complete the prescribed drug course as leaving the course incomplete may lead to the recurrence of infection and drug resistance.

8Side-Effects of Ciplox TZ:

The side effects associated with Ciplox TZ are:

  • Nausea (common)
  • Vomiting (common)
  • Abdominal pain (common)
  • Dizziness (common)
  • Indigestion (common)
  • Altered taste sensation (common)
  • Skin rash (less common)
  • Photo toxicity (Skin susceptibility to light) (less common)
  • Depression (less common)
  • Confusion (less common)
  • Seizures (less common)
  • Tremors (less common)
  • Allergic reactions (rare)
  • Tendonitis (less common)
  • Exacerbation of Myasthenia gravis (rare)

Are There Any Reported Allergic Reactions to Ciplox TZ?

  • Ciplox TZ is known to cause an allergic reaction with symptoms like rashes, breathing difficulty, swelling of face, lip and throat, irregular heartbeat and loss of consciousness.
  • In case of any such signs, immediate medical help should be taken.

What are the effects of Ciplox TZ on organs?

  • Ciplox TZ should used with caution in patients with liver or kidney impairment as it can affect the liver and kidneys.
  • It can affect the central nervous system leading to depression and confusion etc.
  • Ciplox TZ can also lead to tendonitis and rupture of tendons.

9Drug Interactions to be Careful About

It is always advisable to be careful of a certain drug to drug or drug to food interactions when consuming Ciplox TZ. Always be aware of the food items, other drugs or lab tests while consuming Ciplox TZ. We explore these n details below.

1. Food Interactions with Ciplox TZ

Calcium-rich food items are to be avoided.

2. Medicines Interactions with Ciplox TZ

All the potential drug interactions might not be listed here. It is always advisable that the patient must inform the physician about all the drugs/products you use. You must notify the doctor about the herbal products that you are currently consuming. You should never alter the drug regimen without your doctor’s approval.

The common drug interactions have been noticed with the following drugs:

  1. Antacids (moderate): avoid consuming Ciplox TZ 6 hours after and 2hours before taking antacids with aluminum/magnesium as it leads to delayed drug absorption.
  2. Vitamin or mineral supplement containing zinc, calcium or magnesium (mild)
  3. Warfarin (mild)
  4. Caffeine (moderate)
  5. Theophylline (mild)
  6. Tizanidine (severe)
  7. Phenytoin (moderate)
  8. Azole antifungal like ketoconazole (mild)
  9. Cyclosporine (moderate)

3. Effects of Ciplox TZon Lab Tests

Ciplox TZ does not affect any lab tests as such.

4. Ciplox TZ’s interactions with Pre-existing Conditions/Diseases

Any Liver or kidney disease

Q. Can I have Ciplox TZ with alcohol?

No, it is advisable to avoid alcohol consumption while on Ciplox TZ therapy as it can lead to disulfiram reactions (flushing of the face, increased heart rate, thirst, and postural syncope). Therefore, the doctor should always be consulted before taking alcohol with Ciplox TZ.

Q. Any particular food item to be avoided?

Avoid calcium-rich foods and dairy products like milk, yogurt or calcium supplements as they can alter the drug absorption.

Q. Can I have Ciplox TZ when pregnant?

No, it is not safe to consume during pregnancy as it can harm the fetus by crossing the placental barrier. Always inform the doctor before taking Ciplox TZ in cases of pregnancy or if you’re planning to conceive.

Q. Can I have Ciplox TZ when feeding a baby?

No, it is not safe to administer Ciplox TZ tablet to Lactating mothers as the secretion of the Tinidazole in human milk has been established for up to 72hours and can harm the baby. Therefore, inform the doctor always if you’re breastfeeding your child.

Q. Can I drive after taking Ciplox TZ?

Ciplox TZ tablet can cause dizziness or drowsiness in a few rare cases. Therefore, one should avoid driving or operating heavy machinery if drowsiness or dizziness occurs.


10Buyer’s Guide – Ciplox TZ Composition, Variant and Price

Variant Composition Price
Ciplox TZH Tablet Ciprofloxacin 250mg + Tinidazole 300mg Rs. 65.85 for 10 Tablets
Ciplox 2mg/ml 100ml IV Ciprofloxacin 200mg/100ml Rs. 16.76 for 1 pack
Ciplox 500mg Tablet Ciprofloxacin 500mg Rs. 38.34 for 10 tablets
Ciplox OZ Tablet Ciprofloxacin 500mg + Ornidazole 500mg Rs. 79.50 for 10 tablets
Ciplox-D Eye/Ear Drops Ciprofloxacin 0.3%w/v + Dexamethasone 0.1%w/v Rs. 16.50 for 1 pack
Ciplox Eye 5gm ointment Ciprofloxacin 0.3%w/w Rs. 5.70 for 1 pack
Buy & Get Upto 20% Off: Use 1mg Offers | Netmeds Offers | Myra Medicines Offers

11Substitutes of Ciplox TZ

The following are alternative drugs for Ciplox TZ:

  • Microflox CT Tablet:
    • Manufactured by – Micro Labs Ltd
    • Price – Rs. 27.90
  • Cebran TN Tablet:
    • Manufactured by – Blue Cross
    • Price – Rs. 27.80
  • Ciprobid TZ Tablet:
    • Manufactured by – Zydus Healthcare Ltd
    • Price – Rs. 30.9
  • Ciprolet A Tablet:
    • Manufactured by – Dr. Reddy’s Laboratories Ltd.
    • Price – Rs. 33.4

Storage requirements for Ciplox TZ

  • Store the Ciplox TZ tablet at a dry place away from direct heat or sunlight at room temperature.
  • Keep it at a place away from children’s reach.

12FAQs – 10 Important Questions Answered about Ciplox TZ

Q. What is Ciplox TZ?

Ans. Ciplox TZ is a combinational drug that contains Ciprofloxacin and Tinidazole as its main active ingredient.  Ciplox TZ exhibits bactericidal and antiparasitic properties.

It is used mainly to treat conditions like infectious diarrhea, Urinary tract infections, vaginal infections, and pneumonia.

Q. How long does it take for Ciplox TZ to show results?

Ans. The effect of Ciplox TZ can be seen within a few days of starting the Ciplox TZ therapy and the time taken by the drug to show the desired effects may vary with every individual patient.

Q. Should Ciplox TZ be taken on an empty stomach?

Ans.  Ciplox TZ should not be taken empty stomach to prevent any potential stomach upset.

Q. Does Ciplox TZ make you drowsy?

Ans. Ciplox TZ may cause drowsiness in a few cases but it varies with every individual.

Q. What should be the time gap between the consumption of 2 Ciplox TZ doses?

Ans. The ideal time gap of 8-10 hours should be there between two doses.

Q. Should I complete the whole cycle of the medicine even if cured?

Ans. Always complete the prescribed drug course as leaving the course incomplete may lead to the recurrence of infection and drug resistance and the doctor should be the one to decide when and how to stop the cycle of Ciplox TZ.

Q. Does Ciplox TZ effect my menstrual cycle?

Ans. No, it generally doesn’t affect the menstrual cycle but one should always consult the doctor in case of pre-existing menstrual problems before consuming the drug. Ciplox TZ is in fact useful for painful menstruation.

Q. Is Ciplox TZ safe for children?

Ans. Ciplox TZ should not be administered in children without proper consultation and recommendation by the Paediatrician should be taken.

Q. Are there any symptoms that I should consider before taking Ciplox TZ?

Ans. Any liver or kidney disorder or allergic reactions are to be taken into consideration before taking Ciplox TZ.

Q. Is Ciplox TZ legal in India?

Ans. Yes, it is legal in India.


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Disclaimer – The information provided above is to the best of our research and knowledge. However, you are recommended to consult a physician before consuming the drug.

13Authored By

Reviewed and Edited by Dr. Pradeep - Clinical Research Coordinator

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Product Name
Ciplox TZ Tablet
Price
INR 117.19

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