What is Dicyclomine Hydrochloride?

Dicyclomine Hydrochloride is an antispasmodic drug (used to relieve spasm of involuntary muscle) which is used for the treatment of an intestinal problem called functional bowel/irritable bowel syndrome.
Other variants and compositions

Dicyclomine Hydrochloride 30Ml InjectionDicyclomine 10 MG /ML
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How does Dicyclomine Hydrochloride work?

  • Dicyclomine Hydrochloride is an antispasmodic and anticholinergic agent and relieves smooth muscle spasm of the gastrointestinal tract.

Dicyclomine Hydrochloride Price in India

SpecificsDicyclomine Hydrochloride Price
Dicyclomine (20mg), Paracetamol (500 mg) Strip of 10 TabletsRs 11.50

How to Take Dicyclomine Hydrochloride?

  • Available in the form of tablet, capsules, oral suspensions and injections.
  • Dicyclomine Hydrochloride tablets / capsules and suspensions are usually taken by mouth with a glass of water as directed by your doctor, usually 4 times daily before food.
  • For best results, your doctor may direct you to start this medication at a low dose and gradually increase your dose. Follow the instructions carefully.
  • Dicyclomine Hydrochloride injections are always given by a trained healthcare professional.

Common Dosage for Dicyclomine Hydrochloride

  • The drug dosage and form is decided by the physician based upon:
  • age and body weight of the patient
  • health status/medical condition of the patient
  • disease severity
  • reaction to the first dose
  • history of allergy/drug reactions
  • The only oral dose clearly shown to be effective is 160 mg/day (in 4 equally divided doses). Since this dose is associated with a significant incidence of side effects, it is advisable to begin with 80 mg/day (in 4 equally divided doses).
  • Depending upon the patient’s response during the first week of therapy, the dose should be increased to 160 mg per day unless side effects limit dosage escalation.
  • Never use more than the recommended dose or for longer periods of time without Dicyclomine Hydrochloride’s consent.

Also read :  Disodium Hydrogen Citrate Dosage | Disprin Dosage | Dolonex Dt Dosage

Precautions- When to Avoid Dicyclomine Hydrochloride

Dicyclomine Hydrochloride should not be used in the following conditions-

  • Allergy to Dicyclomine Hydrochloride
  • Obstructive disease of the gastrointestinal tract
  • Severe ulcerative colitis
  • Reflux esophagitis
  • Unstable cardiovascular status in acute hemorrhage
  • Glaucoma
  • Myasthenia gravis
  • Evidence of prior hypersensitivity to dicyclomine hydrochloride or other ingredients in this formulation.
  • Infants less than 6 months of age.
  • Nursing Mothers
  • Use with caution in patients with:
  • Autonomic neuropathy
  • Liver or kidney disease
  • Ulcerative colitis
  • Hyperthyroidism
  • Increased blood pressure
  • Heart disease
  • Disorders of heart rhythm
  • Known or suspected prostate enlargement.

Side-effects of Dicyclomine Hydrochloride

  • If the environmental temperature is high, fever and heat stroke can occur with drug use due to decreased sweating.
  • Diarrhea can occur as a side-effect, especially in patients with ileostomy (a surgical operation in which a damaged part is removed from the ileum).
  • Dicyclomine hydrochloride syrups can cause drowsiness or blurred vision.
  • Psychosis can also occur in susceptible individuals.
  • Confusion, disorientation, short-term memory loss, hallucinations, coma, euphoria, decreased anxiety, fatigue, insomnia, agitation and mannerisms, and inappropriate affect can also occur.
  • In infants, Dicyclomine hydrochloride syrup can lead to serious respiratory symptoms (difficulty in breathing, breathlessness, shortness of breath, and respiratory collapse), fits, and loss of consciousness, pulse rate fluctuations, decreased muscular tone, and coma.

Reported Allergic Reactions?

Possible allergic reactions reported include: swelling especially on face, lips & throat, difficulty in breathing or swallowing.

Effect on organs

  • Dose adjustment is needed in patients suffering from kidney and liver diseases.
  • In such patients, Dicyclomine Hydrochloride should be administered with caution.

Drug Interactions to Be Careful About

  • All the possible drug interactions might not be listed here. You must always inform the physician of all the drugs/products you use.
  • You must also inform about the herbal products that you are consuming. You must not modify the drug regimen without your Dicyclomine Hydrochloride’s approval.
  • Some of the common drugs which interact with Dicyclomine Hydrochloride include:
  • amantadine,
  • antiarrhythmic agents e.g., quinidine,
  • antihistamines,
  • antipsychotic agents (e.g., phenothiazines),
  • benzodiazepines,
  • MAO inhibitors,
  • narcotic pain killers (e.g., meperidine),
  • nitrates and nitrites,
  • antidepressants

Shows Effects / Results In:

If efficacy is not achieved within 2 weeks, the drug should be discontinued.

Also Read:  Deriphylline Side Effect | Dexamethasone Side Effect | Dexorange Side Effect

Storage Requirements for Dicyclomine Hydrochloride

  • Store at room temperature, preferably below 86°F (30°C).
  • Protect from excessive heat.

Pro Tips When Taking Dicyclomine Hydrochloride–

  • Dicyclomine Hydrochloride may make you more likely to develop heat stroke as it makes you sweat less.
  • Refrain from activities that may lead you to overheat, such as hard work or work-out in hot weather, or using hot tubs.
  • You must consume a lot of fluids and if you overheat, you must try ti quickly cool down and rest.
Also read about Other Medicine's: Diclofenac Sodium | Drotin Ds


Is Dicyclomine Hydrochloride Addictive?

No such tendency has been reported.

Can I have Dicyclomine Hydrochloride with alcohol?

Patients are advised not to drink alcohol with Dicyclomine Hydrochloride as alcohol intensifies drowsiness.

Any particular food item to be avoided?


Can I have Dicyclomine Hydrochloride When Pregnant?

  • Always inform your doctor if you are pregnant or plan to become pregnant.
  • This drug should be used during pregnancy only if clearly needed.

Can I have Dicyclomine Hydrochloride when feeding a baby?

  • Always inform your doctor if you are breast-feeding your child.
  • Dicyclomine Hydrochloride is excreted in human milk.
  • A decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.

Can I drive after taking Dicyclomine Hydrochloride?

  • Few patients might feel drowsy or dizzy and in such cases it should be used with caution while driving.

What happens if I overdose on Dicyclomine Hydrochloride?

  • It should not be administered in more than prescribed dose.
  • Taking more medication or with increased frequency will not improve your symptoms; rather they may cause serious side-effects.
  • In case of over dosage, consult your doctor immediately.
  • The signs and symptoms of over dosage include: headache; nausea; vomiting; blurred vision; dilated pupils; hot, dry skin; dizziness; dryness of the mouth; difficulty in swallowing; and CNS stimulation including convulsion.

What happens if I eat expired Dicyclomine Hydrochloride?

  • It is very unlikely for a single dose of expired Dicyclomine Hydrochloride to produce an adverse event.
  • However, please consult your physician if you feel unwell or sick after consuming an expired medicine.
  • An expired drug might not be as potent in treating your condition. It is advisable to refrain from using expired drug.

What happens if I miss a dose of Dicyclomine Hydrochloride?

  • The medicine may not work well if you miss a dose because for effective working of the drug, a certain amount of drug must be present in your body at all times.
  • Always consume the missed dose as soon as you remember it. But, if it’s already time to take the second dose after that – do not take double dose.

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