Disodium Hydrogen Citrate: Uses, Dosage, Side Effects, Precautions, Price & More

What is Disodium Hydrogen Citrate?

Disodium Hydrogen Citrate is an acidic salt of citric acid, which is mostly used as a urinary alkalizer (makes the urine more alkaline). It is most commonly available in syrup form and is used in the treatment of urinary tract infection, kidney stones etc.

Buy from here: Netmeds Coupons | Pharmeasy Coupon Codes

Uses of  Disodium Hydrogen Citrate Syrup

Disodium Hydrogen Citrate is used in the treatment of:

  • Acidosis following diarrhoea
  • Urinary tract infections
  • Kidney stones
  • Urinary acidosis
  • Burning micturition
  • Adjuvant therapy with sulphonamides
  • As an antioxidant
  • Disodium hydrogen citrate may also be used in treatment and prevention of signs and symptoms not mentioned above.

Also Read: Dolonex Dt Uses

Disodium Hydrogen Citrate Syrup Price in India

SpecificsDisodium hydrogen citrate Price
100 ml SyrupRs 45*

How does Disodium Hydrogen Citrate Syrup work?

  • Disodium Hydrogen Citrate works by making the urine more alkaline by neutralizing excess acid in the blood and urine.
  • Acidic urine is more prone to the growth of bacteria and thus urinary tract infections. By alkalizing urine, the growth of bacteria is inhibited and thus chances of UTI are reduced.

How to Take Disodium Hydrogen Citrate Syrup?

  • The dosage and duration of this medication should be taken as advised by the doctor. The dosage is based on your age, medical condition, and response to therapy.
  • Avoid taking disodium hydrogen citrate empty stomach.
  • Disodium Hydrogen Citrate should be taken along with plenty of fluids (water/juice etc) to prevent stomach upset.
  • In order to measure the prescribed dose, a medication measuring cup and not a household spoon should be used.
  • Shake the bottle well before each use.
  • If it is taken as over the counter product, check the label for directions before use.

Common Dosage for Disodium Hydrogen Citrate

  • Dosage is usually based on your condition as advised by the doctor. For best results, it should be taken at evenly spaced intervals.
  • Most recommended dose :
  • Adults – 15-30ml dissolved in water twice or thrice daily.
  • Children – 5ml dissolved in water twice or thrice daily.
  • Use with caution in infants and pregnant females.
  • Patients with pre-existing kidney disease and those suffering from dehydration should avoid using this syrup.
  • Never use more than the recommended dose or for longer periods of time without doctor’s consent.
  • In case of non improvement of symptoms or symptoms getting worse, seek medical attention immediately.

Precautions- When to Avoid Disodium Hydrogen Citrate

Disodium Hydrogen Citrate Syrup should not be used in:

  • Allergy to any of its components
  • Patients with moderate to severe renal dysfunction (kidney disease)
  • Dehydrated patients
  • Patients with severe bacterial infection
  • Patients with high potassium levels
  • Patients with a heart problem (irregular heartbeat, heart failure)
  • Pregnant

Side Effects of Disodium Hydrogen Citrate Syrup

Majority of the patients do not show any side effects. However, few patients may show side effects with Disodium Hydrogen Citrate Syrup like:

  • Flatulence
  • Stomach cramps
  • Diarrhoea
  • Anxiety
  • Excessive production of urine
  • Gastrointestinal ulceration
  • Mood swings
  • Feeling of tiredness
  • In addition, it may cause some other allergic or unwanted effects. In such cases, seek medical attention immediately.

What Are the Effects of Disodium Hydrogen Citrate on Organs?

Kidney – Disodium Hydrogen Citrate may be used cautiously in patients with kidney disease. In severe cases, dose adjustment may also be needed. Consult your doctors if any unwanted symptoms are observed.

Are There Any Reported Allergic Reactions?

Report to your doctor if you are allergic to any of its ingredients. Signs of allergic reaction include:

  • Rashes
  • itching of skin
  • Shortness of breath
  • Swelling of face, lips, tongue, or throat
  • Loss of consciousness

Drug Interactions to Be Careful About

All the possible drug interactions might not be listed here. You must always inform the physician of all the drugs/products you use. You must inform your doctor if you frequently use other drugs that make you drowsy or sleepy, such as sleeping pills, other allergy drugs, narcotic pain medicine, muscle relaxants, and drugs used for fits, depression, or anti-anxiety drugs. You must also inform about the herbal products that you are consuming. You must not modify the drug regimen without your doctor’s approval.

Disodium Hydrogen Citrate Syrup may interact with the following drugs and products:

  • Alcohol
  • Tetracycline
  • Barbiturates
  • Corticosteroids
  • Methotrexate
  • Potassium depleting diuretics
  • Amphetamines
  • Salicylates

Shows Effects / Results In

  • Disodium Hydrogen Citrate Syrup starts acting within a few minutes and the effect lasts for 4-6 hours.
  • A complete dose prescribed by your doctor must be taken for the complete cessation of symptoms from your body.

Buy from here: 1MG Coupon Code | Medlife Coupons

Storage Requirements for Disodium Hydrogen Citrate

  • Storage at room temperature away from direct light and heat unless mentioned in the package insert.
  • Do not freeze the medicine.
  • Keep medicinesaway from children and pets.

Pro Tips When Taking Disodium Hydrogen Citrate

Disodium Hydrogen Citrate is unsafe to use in patients with severe kidney disease and should be avoided or the dose should be altered as advised.

Also read about other medicine’s:  Dexorange 


Is Disodium Hydrogen Citrate Syrup addictive?

No. However, self medication and dependence on these medicines should be avoided.

Can I have Disodium Hydrogen Citrate with alcohol?

  • Interaction with alcohol is unknown.
  • However, it may cause excessive drowsiness and calmness in few patients so alcohol should be consumed with caution along with Disodium Hydrogen Citrate.

Any particular food item to be avoided?


Can I have Disodium Hydrogen Citrate when pregnant?

  • Disodium Hydrogen Citrate Syrup can be administered during pregnancy if advised by your doctor.
  • Always inform and consult your doctor if you are pregnant or plan to become pregnant for case specific recommendations.

Can I have Disodium Hydrogen Citrate when feeding a baby?

  • There is no evidence as to whether Disodium Hydrogen Citrate Syrup use has any side effect on lactating mother or baby.
  • Always inform your doctor if you are breast-feeding your child and use the medicine as advised.

Can I drive after taking Disodium Hydrogen Citrate?

If one experiences side effects like drowsiness, headache, dizziness or decrease in blood pressure, then it may not be advisable to drive a vehicle and operate heavy machinery while on this medication.

What happens if I overdose on Disodium Hydrogen Citrate Syrup?

  • It should not be administered in more than prescribed dose. Taking more medication or with increased frequency will not improve your symptoms earlier; rather it may cause serious side-effects.
  • If anyone is suspected of an overdosage, seek medical care immediately.

What happens if I take expired Disodium Hydrogen Citrate?

  • Taking a single dose may not cause any major adverse effect. However, the potency of the medicine may well have been reduced.
  • Please inform your physician regarding the same if expired medicines have been taken chronically for a longer duration.
  • To be on the safer side, always check and never use an expired drug.

What happens if I miss a dose of Disodium Hydrogen Citrate?

  • The medicine may not work well if you miss a dose because for effective working of the drug, a certain amount of drug must be present in your body at all times.
  • Always consume the missed dose as soon as you remember it. But, if it’s already time to take the second dose after that – do not take a double dose.
  • Disodium Hydrogen Citrate should always be taken following meals and with plenty of oral fluids or else chances of gastric side effects increases.
  • Patients on long term Disodium Hydrogen Citrate should be regularly monitored for electrolytes especially sodium and potassium.
CashKaro Medical Expert
CashKaro Blog