Duolin respule: Uses, Dosage, Side Effects, Price, Composition & 20 FAQs

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Duolin respule: Uses, Dosage, Side Effects, Price, Composition & 20 FAQs

What is Duolin respule?

Duolin respule is a combination of two drugs – Ipratropium bromide and Levosalbutamol used for the treatment of bronchial asthma and COPD (chronic obstructive pulmonary disease). It is available in solution form which can also be given orally by nebulisation.

Duolin respule should always be administered under medical supervision as it may lead to several adverse effects like tremor of hands, hypokalemia (decreased blood potassium levels) etc.

Composition: Ipratropium bromide – 500mcg/3ml, Levosalbutamol – 1.25mg/3ml
Manufactured by – Cipla Ltd
Prescription– Prescription needed
Form – Respule
Price – Rs. 58.2
Type of Drug –
Bronchodilator

Read more: Urimax

Uses of Duolin respule

Duolin respule is used for the prevention, treatment and maintenance of:

Read more: Sizodon Uses

How does Duolin respule work?

Duolin respule contains a combination of two medicines – Ipratropium bromide and Levosalbutamol. Levosalbutamol is a beta2 adrenergic bronchodilator whereas Ipratropium bromide is an anti-cholinergic bronchodilator. Together both of them relaxes and widens the airways and makes it easier for breathing.


How to Take Duolin respule ?

  • Duolin is available in respule form which should be used in dose and duration as advised by your doctor.
  • The liquid in the respule should be squeezed into nebulizer after twisting off the top of the respule.
  • It should be administered right after opening and should not be left behind.

Common Dosage for Duolin respule

The drug dosage is decided by the physician based upon:

  • Health status/medical condition of the patient
  • Severity of symptoms
  • Reaction to the first dose
  • History of allergy/drug reactions
  • In adults, one respule as and when required for relief of symptoms. The maximum number of respules that can be used in one day is up to 3 respules.
  • It should not be used in children below 12 years of age.

Q. What happens if I overdose on Duolin respule?

Duolin respule should not be administered in more than prescribed dose. Taking increased dose will not improve your symptoms earlier; rather it may cause serious side-effects like tremor of hands, hypokalemia (decreased blood potassium levels) etc.  In case of over dosage, consult your doctor immediately.

Q. What happens if I miss a dose of Duolin respule?

The potency of the medicine may decrease because for effective working of the drug, a certain amount of drug must be present in your body at all times. Always consume the missed dose as soon as you remember. But, if it’s already time for the next dose – do not double the dose.

Q. What happens if I eat expired Duolin respule?

The medicine may not work as well as the potency of the medicine gets affected. Please inform your physician regarding the same. To be on the safer side, always check and never use an expired medicine.

Q. What is the onset time of Duolin respule?

The effect of Duolin respule can be observed within 2 hours of administration of dose.

Q. Till when does the effect of Duolin respule stay?

The duration of time for which the medicine remains effective varies from 6-8 hours.


When to avoid Duolin respule?

Duolin respule should not be used in the following conditions:

  • Allergic to any of its components
  • Status asthmaticus (acute episode of asthma)
  • Pregnancy and breast feeding mothers
  • Patients with cardiovascular disease
  • Epileptic patients

Precautions While Taking Duolin respule

Patients with glaucoma and cardiovascular disease should use Duolin respule with caution as it may lead to adverse effects.


Side-Effects of Duolin respule

Duolin respule may produce multiple side effects, although they may not be common in all the patients. Commonly observed side effects:

  • Throat irritation (common)
  • Headache (common)
  • Weakness (common)
  • Nausea (less common)
  • Vomiting (less common)
  • Stomach pain (less common)
  • Tremor (less common)
  • Hypokalemia (decreased blood potassium levels)
  • Palpitation (less common)
  • Muscle cramp (less common)

In addition, it may also cause some allergic or unwanted effects. In such cases, seek medical attention immediately.

Are There Any Reported Allergic Reactions to Duolin respule?

Tell your doctor if you are allergic to any of its ingredients.

Signs and symptoms include:

  • Rash (common)
  • Itching (common)
  • Shortness of breath (less common)
  • Swelling of face, lips, tongue, or throat (rare)
  • Loss of consciousness (rare)

 What are the effects of Duolin respule on organs?

  • Patients with glaucoma and blurred vision should use Duolin respule with caution as it may lead to increased intraocular pressure.
  • Patients with diseases of cardiovascular system should use Duolin respule with extreme caution as it is associated with serious adverse effects like palpitations, changes in heart rate, dizziness etc.

Drug Interactions to be Careful About

Drug interaction refers to effect of drugs on each other and on human body after ingestion. Large numbers of medicines have shown to interact with each other. Interactions are not just limited to drugs, but certain food items and some laboratory tests which should not be taken right after consuming Duolin respule. We explore these in details below.

1. Food Interactions with Duolin respule

No interaction observed with any food products.

2. Medicines Interactions with Duolin respule

It is always advised that the patient must inform the physician about all the drugs/over the counter products/vitamin supplements used.It may interact with the following drugs and products:

  • Beta blockers (severe)
  • Ketaconzole (severe)
  • Amiodarone (moderate)
  • Digoxin (moderate)
  • Glucocorticosteroids (moderate)
  • Tricyclic antidepressants (moderate)

 3. Effects of Duolin respule on Lab Tests

No effect on any lab tests noted while taking Duolin respule.

4. Interactions with Pre-existing Conditions/Diseases

Patients suffering from pre-existing heart disease and ocular (eye) diseases should use Duolin respule with caution as it may lead to worsening of patient’s condition.

Q. Can I have Duolin respule with alcohol?

Concomitant administration of Duolin respule with alcohol should be avoided as it may increase the risk of adverse effects like dizziness, drowsiness and confusion.

Q. Any particular food item to be avoided?

No alteration in its action seen with any food product.

Q. Can I have Duolin respule when pregnant?

Duolin respule should be avoided during pregnancy as it may lead to adverse effects in foetus. It should only be used if the potential benefits justify the risks to the foetus.

Q. Can I have Duolin respule when feeding a baby?

Duolin respule should be used with caution in breastfeeding women as the drug may pass into breast milk and lead to adverse effects in foetus. Always inform your doctor before if you are breast-feeding your child.

Q. Can I drive after taking Duolin respule?

Duolin respule doesn’t affect your ability to drive. Few patients have reported headache and dizziness as adverse effects.

Read more: Lesuride Side Effects

Duolin respule  – Composition, Variant and Price– Buyer’s Guide

Duolin respule Variants Duolin respule Composition Duolin respule Price (Rs.)
Duolin inhaler  Ipratropium bromide – 20mcg

Levosalbutamol – 50mcg

 Rs. 256.3
 Buy & save from: Myra Medicines | 1mg | Practo

Substitutes of Duolin respule

The following are alternative drugs for Duolin respule:

  • Combimist L respule
    • Manufactured by – German remedies
    • Price – Rs. 82
  • Salbair I
    • Manufactured by – Lupin Ltd
    • Price – Rs. 164
Read more: Imipramine Price

Storage requirements for Duolin respule

  • Storage at room temperature away from direct light and heat unless mentioned in the package insert.
  • Keep medicines away from children and pets.

FAQs – 10 Important Questions Answered about Duolin respule

Q. What is Duolin respule?

Duolin respule is a combination of two drugs – Ipratropium bromide and Levosalbutamol used for the treatment of bronchial asthma and COPD (chronic obstructive pulmonary disease). It is available in solution form which can also be given orally by nebulisation.

Q. What are the uses of Duolin respule?

It is used for the treatment of bronchial asthma and COPD (chronic obstructive pulmonary disease)

Q. What are the side effects of Duolin respule?

Ans. The most common side effects of Duolin respule are Throat irritation, Headache, Weakness, Nausea, Vomiting, Stomach pain

Q. Should Duolin respule be taken on an empty stomach?

Duolin respule can be taken empty stomach or after meals.

Q. Does Duolin respule make you drowsy?

Yes Duolin respule may make you feel dizzy and drowsy.

Q. What should be the time gap between the intakes of two Duolin respule doses?

There should be a time gap of at least 8-12 hours between two doses of Duolin respule.

Q. Should I complete the whole cycle of the medicine even if cured?

A complete course prescribed by your doctor must be taken for complete cessation of symptoms from your body.

Q. Does Duolin respule effect my menstrual cycle?

No, Duolin respule does not affect your menstrual cycle.

Q. Is Duolin respule safe for children?

Duolin respule is safe for consumption in children above 12 years of age. Children below 12 years should use it with caution.

Q. Are there any symptoms that I should consider before taking Duolin respule?

Patients with Glaucoma, cardiovascular (heart) disease should use Duolin respule with caution.

Q. Is Duolin respule legal in India?

Yes, it is legal.


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Disclaimer – The information provided above is to the best of our research and knowledge. However, you are recommended to consult a physician before consuming the drug.

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