Entozyme syrup: Uses, Dosage, Side Effects, Price, Composition & 20 FAQs

Entozyme syrup contains digestive enzymes fungal diastase and pepsin which help in treatment of digestive disorders like indigestion, dyspepsia and flatulence. These natural enzymes are used for breaking down and digesting food. It is available in syrup form for oral administration and is available as an over the counter product.

Composition: Fungal diastase – 50mg/5ml, Pepsin – 10mg/5ml
Manufactured by – Biophar Lifesciences
Prescription– Available as OTC drug
Form – Syrup
Price – Rs. 92
Type of Drug – Digestive Enzyme 

Entozyme syrup is most commonly used in the prevention and treatment of the following conditions:

• Digestive disorders
• Starch Indigestion
• Flatulence
• Bloating
• Stomach cramps
• Patients with chronic pancreatitis, pancreatic cancer and patients in which pancreas have been surgically removed – in these cases, pancreas do not release enough digestive enzymes so Entozyme syrup is used as a supplement or replacement therapy.

Entozyme syrup contains digestive enzymes which help in breaking down complex proteins and carbohydrate molecules present in food into smaller and easily digestible particles.

• Although Entozyme syrup is available as an over the counter product, it is important to seek medical advice before using it.
• It is advised to take this medicine with food or immediately after food.
• In order to measure the prescribed dose, a medication measuring device and not a household spoon should be used.
• Shake the bottle well before each use.
• In case of non improvement of symptoms or symptoms getting worse, seek medical attention immediately.

• The dosage of the drug is to be decided by the doctor for every individual as per the age, weight, mental status, allergic history of the patient.
• For adult patients, the recommended dose is 5-10ml syrup once or twice a day after meals depending upon the severity of symptoms or as advised by the doctor.

Q. What happens if I overdose on Entozyme syrup?

Entozyme syrup should not be administered in more than prescribed dose. Taking increased dose will not improve your symptoms earlier; rather it may cause some side effects. In case of over dosage, consult your doctor immediately.

Q. What happens if I miss a dose of Entozyme syrup?

The potency of the medicine may decrease because for effective working of the drug, a certain amount of drug must be present in your body at all times. Always consume the missed dose as soon as you remember. But, if it’s already time for the next dose – do not double the dose.

Q. What happens if I eat expired Entozyme syrup?

The medicine may not work as well as the potency of the medicine gets affected. Please inform your physician regarding the same. To be on the safer side, always check and never use an expired medicine.

Q. What is the onset time of Entozyme syrup?

You should start to feel recovered within few minutes to one hour after oral administration.

Q. Till when does the effect of Entozyme syrup stay?

The duration of time for which the medicine remains effective is 4-6 hours.

Entozyme syrup should not be used in the following conditions:

• Allergy to any of its components
• Patients with Intestinal perforation or severe intestinal infection
• Crohn’s disease (digestive disorder characterised by inflammation of digestive tract)
• Gout (high amount of uric acid in blood)
• Formation of fibrous tissue in colon

Inform your doctor about all the current list of medicines, allergies and pre-existing health conditions like intestinal obstruction, Crohn’s disease before you start taking Entozyme syrup.

Majority of the patients do not show any side effects. Few patients might show side effects which include:

• Abdominal pain (common)
• Stomach upset (common)
• Nausea (less common)
• Painful urination (less common)
• Acute toxicity (rare)

Are There Any Reported Allergic Reactions to Entozyme syrup?

Tell your doctor if you are allergic to any of its ingredients. Signs and symptoms include:

• Rash ( less common)
• Itching (less common)
• Shortness of breath (less common)
• Swelling of face, lips, tongue, or throat (rare)
• Loss of consciousness (rare)

What are the effects of Entozyme syrup on organs?

Entozyme syrup does not affect any organs.

Drug interaction refers to effect of drugs on each other and on human body after ingestion. Large numbers of medicines have shown to interact with each other. Interactions are not just limited to drugs, but certain food items and some laboratory tests which should not be taken right after consuming Entozyme syrup. We explore these in details below.

1. Food Interactions with Entozyme syrup

No interactions observed with any food products.

2. Medicines Interactions with Entozyme syrup

It is always advised that the patient must inform the physician about all the drugs/over the counter products/vitamin supplements used. Entozyme syrup does not usually affect with common drugs however It may interact with few drugs like:

• Acarbose
• Miglitol

3. Effects of Entozyme syrup on Lab Tests

No effect on any lab tests noted while taking Entozyme syrup.

4. Interactions with Pre-existing Conditions/Diseases

Entozyme syrup does not interact with any other disease or condition.

Q. Can I have Entozyme syrup with alcohol?

Interaction of Entozyme syrup with alcohol is unknown.

Q. Any particular food item to be avoided?

Entozyme syrup acts as a digestive supplement. No alteration in its action seen with any food product.

Q. Can I have Entozyme syrup when pregnant?

Entozyme syrup can be administered in pregnancy if the benefits outweigh the risks associated and if advised by your doctor. Always inform your doctor if you are pregnant or plan to become pregnant.

Q. Can I have Entozyme syrup when feeding a baby?

Entozyme syrup is safe to take if you are breastfeeding or planning to start breastfeeding a baby. However, it is advisable that you should consult a doctor and share your plans of breast feeding before taking this medicine.

Q. Can I drive after taking Entozyme syrup?

Entozyme syrup does not affect your ability to drive.

The following are alternative drugs for Entozyme syrup:

• Aristozyme syrup
  • Manufactured by – Aristo Pharmaceutical Pvt Ltd
  • Price – Rs. 84

• Unienzyme syrup
  • Manufactured by – Torrent Pharmaceutical Ltd
  • Price – Rs. 83
• Ritozyme syrup
  • Manufactured by – MHS Pharmaceuticals
  • Price – Rs. 46

Storage requirements for Entozyme syrup

• Storage at room temperature away from direct light and heat unless mentioned in the package insert.
• Keep medicines away from children and pets.

Q. What is Entozyme syrup?

Entozyme syrup contains digestive enzymes fungal diastase and pepsin which help in treatment of digestive disorders like indigestion, dyspepsia and flatulence. These natural enzymes are used for breaking down and digesting food. It is available in syrup form for oral administration and is available as an over the counter product.

Q. What are the uses of Entozyme syrup?

It helps in treatment of digestive disorders like indigestion, dyspepsia and flatulence.

Q. What are the side effects of Entozyme syrup?

Ans. The most common side effects of Entozyme syrup are Abdominal pain, Stomach upset, Nausea, Painful urination, Acute toxicity

Q. Should Entozyme syrup be taken on an empty stomach?

Entozyme syrup should only be taken after meals. It is not advised to take it empty stomach.

Q. Does Entozyme syrup make you drowsy?

No, Entozyme syrup does not cause drowsiness in majority of the patients.

Q. What should be the time gap between the intakes of two Entozyme syrup doses?

Entozyme syrup is usually recommended as a single daily dose. If taken more than once, time duration of 8-12 hours is must between two doses.

Q. Should I complete the whole cycle of the medicine even if cured?

A complete course prescribed by your doctor must be taken for complete cessation of symptoms from your body.

Q.. Does Entozyme syrup effect my menstrual cycle?

No, Entozyme syrup does not affect your menstrual cycle.

Q. Is Entozyme syrup safe for children?

Entozyme syrup is safe for consumption in children. However it is usually administered only in adults.

Q. Are there any symptoms that I should consider before taking Entozyme syrup?

Patients with intestinal obstruction and Gout should use Entozyme syrup only under supervision of a doctor.

Q. Is Entozyme syrup legal in India?

Yes, it is legal.

Disclaimer – The information provided above is to the best of our research and knowledge. However, you are recommended to consult a physician before consuming the drug.