Enzoflam D Tablet: Uses, Dosage, Side Effects, Price, Composition & 20 FAQs

It is mainly used to prevent or treat signs of inflammation like redness, swelling, pain etc. (back pain, osteoarthritis), toothache and fever. Dry mouth and dizziness are the most commonly seen side effect at high repetitive doses. It should be totally avoided in case of liver, kidney or heart impairment and gastric ulcers.

Enzoflam Composition: Diclofenac 50mg + Paracetamol 325mg + Serratiopeptidase 15mg
Manufactured By: Alkem Laboratories Ltd
Prescription: Required as it belongs to Schedule ‘H’ but also available as OTC
Form: Tablet and gel.
Price: Rs. 114.50 for 10 tablets.
Expiry/Shelf Life: 24 months from the date of manufacturing
Type of Drug: NSAID + Analgesic + Antipyretic

Also read in Hindi about Enzoflam

Enzoflam is used to prevent or treat following conditions:

• Back pain: Used to treat back pain caused by sciatica and arthritis.
• Ankylosing Spondylitis: Used in cases of ankylosing spondylitis to treat symptoms like pain and stiffness.
• Frozen Shoulder: Used to treat pain in cases of frozen shoulder
• Menstrual Pain: Used to treat and manage pain during periods (menstruation pain) and provides relief in menstrual cramps.
• Dental Pain: Used to treat tooth pain caused by infection and decay of tooth.
• Osteoarthritis: Used in cases of Osteoarthritis and provides relief in joint pain and stiff muscles.
• Rheumatoid Arthritis: Used in cases of rheumatoid arthritis.
• Fever: Used in cases of mild to moderate fever as it contains Paracetamol.
• Headache: Also used to treat mild to moderate headache.
• Post Surgical pain: Used to manage the post operative or post surgical pain.
• Others: Used to treat mild cases of fever due to its antipyretic property.
• Bursitis: Used in cases of inflammation of lubricating fluid sacs in joints known as Bursitis.
• Tendonitis: Used in cases of inflammation of tendon, example tennis elbow known as tendonitis.

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• Enzoflam contains Diclofenac, Paracetamol and Serratiopeptidase as its main active ingredient.
• Diclofenac is a Non steroidal anti inflammatory drug (NSAID) used to treat pain and other signs of inflammation.
• It works by inhibiting the COX (Cyclo oxygenase) enzymes which further blocks prostaglandin secretion.
• Prostaglandins are accountable for producing inflammatory signs and inhibition of prostaglandin aids in providing relief from the symptoms
• Paracetamol selectively inhibits the COX enzymes in brain which aids for its analgesic and antipyretic property.
• Serratiopeptidase works by breaking down the anomalous proteins at the injury site and promotes healing.

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• Enzoflam is usually available in the form of tablets and gel.
• Enzoflam Tablet is taken by mouth with a glass of water preferably with or after meals as food helps to prevent any potential gastric irritation the drug might cause when taken empty stomach.
• Enzoflam Tablet should never be chewed or crushed. It should be swallowed as a whole.
• Enzoflam Tablet should be taken with equal time interval of atleast 4-6 hours between two doses, if more than one dose a day is prescribed.
• It is advisable to go through the pack insert properly before consuming the drug to have a better understanding of the drug.

• The dosage of the drug is to be decided by the doctor for every individual as per the age, weight, mental status, allergic history of the patient.
• Common Adult dose of Enzoflam Tablet is a single tablet once or twice a day with an interval of at least 4-6 hours between two doses.
• It is not recommended to be administered to children below 12 years of age without pediatric consultation
• Dose alteration should be avoided without proper medical consultation.

Q. What happens if I overdose on Enzoflam?

Overdose of Enzoflam can cause undesirable effects like nausea, vomiting, stomach discomfort and lethargy and can also lead to complications in few cases.
Therefore, strictly adhere to the prescribed dose and seek medical help immediately in case of any symptoms of overdose.

Q. What happens if I miss a dose of Enzoflam?

Dose prescribed by the doctor should never be missed and if missed, it should be consumed always as soon as you remember it. But, avoid taking a double dose if it’s already time for the second dose after that as it may lead to overdose of the drug

Q. What happens if I eat expired Enzoflam?

Consuming expired Enzoflam tablet might not exhibit desirable effects or any side effects. However, one should abstain from consuming expired drug.

Q. Onset time of Enzoflam?

The effect of Enzoflam can be seen within 30 minutes of oral administration of the drug.

Q. Till when does the effect of Enzoflam stays?

Time taken by drug to show the desired effects may vary with every individual patient.

Do not Consume Enzoflam if:

• Allergy: In cases of known allergy to Enzoflam or any other NSAIDs or any of its constituents.
• Gastric bleeding: In cases of patients with history of gastric ulcer, bleeding or perforations as it can cause swelling and bleeding of stomach, colon or anus.
• Asthma: In cases of patients with Asthma.
• Liver/ Kidney impairment: In cases of patients with liver disease and kidney disease or impairment.

• Elderly patients: Enzoflam or any other NSAID should be used with caution in elderly patients as they are at high risk of serious side effects and fatalities.
• Liver/ Kidney diseases: Dose alteration may be required by the physician in patients with kidney, heart or liver impairments.
• GI lesions: Enzoflam should be used with extra caution in patients with history of gastrointestinal lesions.
• Low doses: Enzoflam should always be consumed at the lowest possible effective dose.

Warnings When Taking Enzoflam

• Prolonged use can increase the risk of heart attack in patients already suffering from heart diseases.
• There should be equally spaced time interval between two doses.
• Consume plenty of fluids to counteract the potential undesirable effects of the drug.
• Always consume the tablet with or after meals to prevent any gastric irritation.
• Do not take two different kinds of pain killer concomitantly.

The side effects associated with Enzoflam are:

• Nausea (common)
• Vomiting (common)
• Abdominal pain (less common)
• Diarrhoea (less common)
• Dizziness (common)
• Dry Mouth (common)
• Dry skin (less common)
• Indigestion (common)
• Flatulence (less common)
• Constipation (less common)
• Loss of appetite (less common)

Are There Any Reported Allergic Reactions to Enzoflam?

• Enzoflam is known to cause allergic reaction with symptoms like rashes, breathing difficulty, swelling of face, lip and throat, irregular heartbeat and loss of consciousness.
• In case of any such signs, immediate medical help should be taken.

 What are the effects of Enzoflam on organs?

• Enzoflam should used with caution in patients with liver impairment as it can affect the liver.
• It can cause stomach bleeding in patients with gastric ulcer.

It is always advisable to be careful of certain drug to drug or drug to food interactions when consuming Enzoflam. Always be aware of the food items, other drugs or lab tests while consuming Enzoflam. We explore these n details below.

1. Food Interactions with Enzoflam

No particular food item to be avoided.

2. Medicines Interactions with Enzoflam

 All the potential drug interactions might not be listed here. It is always advisable that the patient must inform the physician about of all the drugs/products you use. You must notify the doctor about the herbal products that you are currently consuming. You should never alter the drug regimen without your doctor’s approval.

The common drug interactions have been noticed with the following drugs:

1. ACE Inhibitors (mild)
2. Aldosterone antagonists (moderate)
3. Alendronate (mild)
4. Amiloride (severe)
5. Aspirin (severe)
6. Beta blockers (mild)
7. Brimonidine (moderate)
8. Calcineurin inhibitors (mild)
9. Captopril (mild)
10. Clopidogrel (mild)
11. Corticosteroids (moderate)
12. Cyclosporin (moderate)
13. Dalteparin (mild)
14. Diclofenac (moderate)
15. Enoxaparin (mild)
16. Fluconazole (moderate)
17. Heparin (moderate)
18. Ibuprofen (mild)
19. Lithium(severe)
20. Loop diuretics (moderate)
21. Methotrexate (severe)
22. Phenindione (moderate)
23. Potassium (mild)
24. Prostaglandin analogues (mild)
25. Rifampicin (mild)
26. Tacrolimus (moderate)
27. Thiazide diuretics (moderate)
28. Triamterene (mild)
29. Warfarin (moderate)

3. Effects of Enzoflam on Lab Tests

 Enzoflam does not affect any lab tests as such.

4. Enzoflam’s interactions with Pre-existing Conditions/Diseases

Any Liver or kidney diseases and gastric ulcer.

Q. Can I have Enzoflam with alcohol?

No, it is advisable to avoid alcohol consumption while on Enzoflam therapy as it can increase the chances of stomach bleeding. Therefore, the doctor should always be consulted before taking alcohol with Enzoflam.

Q. Any particular food item to be avoided?

No particular food item is to be avoided.

Q. Can I have Enzoflam when pregnant?

No, it is not safe to consume during pregnancy (especially in the first and third trimester of pregnancy) as it can harm the foetus. Always inform the doctor before taking Enzoflam in cases of pregnancy or if you’re planning to conceive.

Q. Can I have Enzoflam when feeding a baby?

No, it is not safe to administer Enzoflam tablet to Lactating mothers as the secretion of the drug in human milk is not known and the drug should be used only when necessary and with caution after informing the doctor about the case.

Q. Can I drive after taking Enzoflam?

Enzoflam tablet can cause dizziness or drowsiness in some cases. Therefore, one should avoid driving or operating heavy machinery if drowsiness or dizziness occurs.

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The following are alternative drugs for Enzoflam:

• Rigesic Tablet:
  • Manufactured by Rizer
  • Price – Rs. 97
• Diclomore SP Tablet:
  • Manufactured by Unichem
  • Price – Rs. 39
• Diclogesic SP Tablet:
  • Manufactured by Torrent Pharmaceuticals Ltd
  • Price – Rs. 68.7
• Distil P Tablet:
  • Manufactured by General.

Storage requirements for Enzoflam

• Store the Enzoflam tablet at a dry place away from direct heat or sunlight at temperature below 25^O
• Keep it at a place away from children’s reach.

Q. What is Enzoflam?

Ans. Enzoflam is a combinational drug that contains Diclofenac, Paracetamol and Serratiopeptidase as its main active ingredient.  Enzoflam exhibits Non steroidal anti inflammatory drug (NSAID) with analgesic (Pain reliever) and anti inflammatory properties whereas, Paracetamol is analgesic as well anti pyretic in nature. It is used mainly to treat signs of inflammation like redness, swelling, pain etc. and conditions like pain of osteoarthritis, toothache and gout.

Q. What are the uses of Enzoflam?

Ans. It is used mainly to treat signs of inflammation like redness, swelling, pain etc. and conditions like pain of osteoarthritis, toothache and gout.

Q. What are the side effects of Enzoflam?

Ans. The most common side effects of Enzoflam are Nausea, Vomiting, Abdominal pain, Diarrhoea, Dizziness, Dry Mouth, Dry skin, Indigestion, Flatulence

Q. How long does it take for Enzoflam to show results?

Ans. The effect of Enzoflam can be seen within 30 minutes of oral administration of the drug and the time taken by drug to show the desired effects may vary with every individual patient.

Q. Should Enzoflam be taken on an empty stomach?

Ans. Enzoflam should not be taken empty stomach to prevent any potential stomach upset.

Q. Does Enzoflam make you drowsy?

Ans. Yes, Enzoflam may cause drowsiness in few cases but it varies with every individual.

Q. What should be the time gap between the consumption of 2 Enzoflam doses?

Ans. Ideal time gap of 4-6 hours should be there between two doses.

Q. Should I complete the whole cycle of the medicine even if cured?

Ans. Enzoflam should be consumed as prescribed by the doctor and in case of any severity of symptoms, immediate medical help or consultation should be taken. And the doctor should be the one to decide when and how to stop the cycle of Enzoflam.

Q. Does Enzoflam effect my menstrual cycle?

Ans. No, it generally doesn’t affect the menstrual cycle but one should always consult the doctor in case of pre existing menstrual problems before consuming the drug. Enzoflam is infact useful for painful menstruation.

Q. Is Enzoflam safe for children?

Ans. Enzoflam should not be administered in children without proper consultation and recommendation by the Paediatrician should be taken.

Q. Are there any symptoms that I should consider before taking Enzoflam?

Ans. Any liver or kidney disorder or allergic reactions are to be taken into consideration before taking Enzoflam.

Q. Is Enzoflam legal in India?

Ans. Yes, it is legal in India.

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Disclaimer – The information provided above is to the best of our research and knowledge. However, you are recommended to consult a physician before consuming the drug.