FARXIGA: Uses, Dosage, Side Effects, Price, Composition, Precautions & More

What is Farxiga?

  • Farxiga is an oral anti-diabetic drug which is used to lower the blood glucose levels in type 2 diabetic patients.
  • Farxiga should be used along with dietary changes and exercise to control hyperglycaemia. It should not be used in patients with type 1 diabetes.
  • Farxiga contains “Dapagliflozin” as its active ingredient and is available in tablet form for oral administration.
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Uses of Farxiga

  • Used to lower blood glucose levels in type 2 diabetic patients
  • It should not be used in type 1 diabetics and patients with diabetic ketoacidosis.

 How does Farxiga work?

Farxiga is a sodium glucose co-transporter 2 (SGLT2) inhibitors which controls blood sugar levels by increasing the level of sugar removed by kidneys.

Price of Farxiga In India:

Specifics  Farxiga Price
5mg Strip Rs. 630.00
Also Read: Gleevec Price

How to Take Farxiga?

  • The dosage and duration of treatment with Farxiga is based on your age, severity of condition, physical health, and response to therapy.
  • Farxiga should always be taken just before the first meal of the day (usually breakfast). Skipping meals should be avoided. For ideal results, it should always be taken at a fixed time.
  • The tablet should be swallowed as a whole without crushing, chewing or breaking it along with plenty of fluids.
  • Farxiga should not be stopped on your own without doctor’s consent or before the complete course.
  • Non pharmacologic therapy (dietary modification, weight control and exercise) is equally essential to reduce blood glucose levels along with Farxiga therapy.
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 Common Dosage for Farxiga

  • There is no fixed dose regimen of Farxiga for the treatment of diabetes. Constant monitoring of blood glucose levels and dose variation accordingly is must.
  • To reduce the risk of side effects, your doctor may initially start from a low dose and gradually increase your dose based on your condition.
  • The usual starting dose of Farxiga is 5mg tablet once daily taken before the first meal of the day.
  • The dose can be increased up to 10mg once daily in patients requiring additional glycaemia control.
  • It should be used with caution in patients with history kidney disease. Assess renal functions before initiating and increasing the dose of Farxiga.

Precautions – When to Avoid Farxiga?

Farxiga should be avoided or used with caution in:

  • Patients with allergy to any of its components
  • Type 1 diabetes (insulin dependent diabetes)
  • Diabetic ketoacidosis (complication of diabetes associated with building up of acids)
  • Severe kidney disorders or patients on dialysis.
  • Severe liver disorders
  • Pregnant and lactating females
  • Children below 18 years of age
Also Read: Gamma Benzene Hexachloride Precaution

 Side-Effects of Farxiga

  • In addition to its intended uses, Farxiga may cause few undesirable side effects which may include:
  • Hypoglycaemia – most commonly observed if patients take this medicine in higher doses than required or with other diabetic medications like insulin or insulin secretagogue. Symptoms of hypoglycaemia (low blood glucose) include:
  • Restlessness
  • Headache
  • Sleepiness
  • Impaired concentration
  • Depression
  • Confusion
  • Tremor
  • Dizziness
  • Palpitations
  • Tachycardia (increased heart beat)
  • Anxiety
  • Fatigue
  • Sweating

Other less commonly observed side effects include:

  • Frequent urination
  • Increased thirst
  • Hypotension
  • Dizziness
  • Light headedness
  • High potassium levels
  • Kidney problems
  • Genital fungal infections
  • Urinary tract infections
  • In addition it may cause some other allergic or unwanted effects. In such cases, seek medical attention immediately.
Also Read: Gamma Benzene Hexachloride Side Effects

Effect of Farxiga on organs?

  • Liver & Kidney – Patients with pre-existing liver and kidney disease should use Farxiga with caution as it can cause severe hepatic and renal impairment.
  • Assess kidney function test before initiating and increasing the dose of Farxiga therapy.

Reported Allergic Reactions?

  • Allergic reactions with Farxiga have been reported. Inform your doctor if you are allergic to any of its ingredients.
  • Signs of allergic reaction include:
  • Rashes/itching of skin
  • Shortness of breath
  • Swelling of face, lips, tongue, or throat
  • Loss of consciousness

Drug Interactions to Be Careful About

  • Drug interactions refer to effect of drugs on each other and on human body after ingestion. There are large numbers of medicines which have shown to interact with each other. 
  • All the possible drug interactions might not be listed here. Few important drugs which interact with Farxiga are listed below:
  • Alcohol
  • Insulin or other anti-diabetic drugs
  • Rifampicin
  • Phenytoin
  • Digoxin
  • Ritonavir
  • Propanolol
  • Using all these products along with Farxiga can influence the therapeutic effect of these medicines and also can increase the chances of side effects
  • Thus dose alteration or drug replacement might be needed when Farxiga is taken along with these drugs.

 Shows Effects / Results After Consuming Farxiga:

  • Farxiga starts showing its effect within 24-48 hours by reducing the blood glucose levels. However, maximum effect takes some time depending upon the severity of condition.
  • A complete dose prescribed by your doctor must be taken for complete diabetes control even if symptoms have disappeared.

Storage Requirements about Farxiga

  • Store at cool and dry place away from direct heat and moisture.
  • Do not freeze the medicine.
  • Keep medicine away from children and pets.

Pro Tips When Taking Farxiga

Farxiga tablets should be administered along with non pharmacologic therapy (proper dietary modification, weight control and exercise) to achieve best results. In early type 2 diabetes, only non pharmacologic therapy may well provide ideal results.

 FAQs – Things to Know About Farxiga

Is Farxiga addictive?

No habit forming tendency has been reported. However over dependence to these medicines should be avoided.

Can I have Farxiga with alcohol?

Consumption of alcohol is not recommended when on Farxiga therapy as it may affect the blood glucose levels. Consult your doctor for further recommendations.

Any particular food item to be avoided?

No alteration in its action seen with any food product.

 Can I have Farxiga when pregnant?

  • Farxiga is not recommended during pregnancy as it may be associated with higher incidence of congenital abnormalities especially when used during third trimester.
  • Consult your doctor in case if you are pregnant or plan to become pregnant for case specific recommendations.

Can I have Farxiga when feeding a baby?

  • Farxiga is not recommended for use while you are breast feeding as the drug may pass into breast milk and may harm the foetus by decreasing blood sugar levels.
  • Consult your doctor for case specific recommendations.

Can I drive after taking Farxiga?

Farxiga intake doesn’t affect your ability to drive. However hypoglycaemia caused due to over dosage or when used with other diabetic drugs and hyperglycaemia due to improper dosage may cause drowsiness, fatigue, impaired concentration, sleepiness etc which may hinder with driving and operating heavy machinery.

What happens if I overdose on Farxiga?

  • Farxiga should never be administered in more than prescribed dose.
  • Taking more medication or with increased frequency may cause serious Hypoglycaemia (symptoms of which have been mentioned above)
  • If suspected of an over-dosage, seek medical care immediately.

What happens if I take expired Farxiga?

  • A single dose of expired Farxiga may not cause any major adverse effect. However, the potency of the medicine may well have decreased overtime and it may cause hyperglycaemia (increased blood glucose levels).
  • Please inform your physician regarding the same if expired medicines have been taken chronically for a longer duration.

What happens if I miss a dose of Farxiga?

  • The medicine may not work well if you miss a dose because a certain amount of drug must be present in your body at all times for its effective working,
  • If you forgot to take a dose, take it as soon as you remember. But, if it’s already time to take the second dose – do not take double dose.

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