Gefitinib: Uses, Dosage, Side Effects, Price, Composition, Precautions & More

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Gefitinib: Uses, Dosage, Side Effects, Price, Composition, Precautions & More

What Is Gefitinib?

Gefitinib is a cancer chemotherapy agent used in treating non-small lung cancer after other cancer chemotherapy treatments have not been successful.

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Uses Of Gefitinib

Gefitinib is used to treat non-small lung cancer that has spread to other parts of the body.

Also Read: Glynase uses | Doxovent uses | Lamisil uses

How Does Gefitinib Work?

  • An enzyme called epidermal growth factor receptor tyrosine kinase (EGFR-TK) is overexpressed in people with non-small lung cancer and certain other types of cancers like head and neck cancer.
  • Gefitinib acts by inhibiting this EGFR-TK enzyme, thus stopping further growth of cancer cells.

Gefitinib Price in India

Specifics  Gefitinib Price
Bottle of 30 tablets of Krypton Gefitinib 250mg Rs. 6500

How to Take Gefitinib?

  • Gefitinib comes in tablet form to be taken by mouth.
  • It can be taken with or without food once in a day.
  • Take Gefitinib at around the same time every day for maximum benefits.

Common Dosage Of Gefitinib

  • The usual adult dosage of Gefitinib is 250mg once in a day.
  • This dosage may be increased up to 500mg with close monitoring of the patient.
  • Dosage adjustments are required in people with liver and kidney diseases.

When to Avoid & Gefitinib Precautions To Take?

  • Gefitinib is contraindicated in patients suffering from Intestinal Pneumonitis and/or Lung fibrosis.
  • Gefitinib should be avoided in people have a severe renal impairment or liver diseases.
  • Gefitinib should be avoided during pregnancy and breastfeeding.
Read More: Gabantin precautions | Duofilm Precautions | Ketanov precautions

Side Effects Of Gefitinib

Common side effects of Gefitinib include –

  • Acne
  • Dry skin
  • Diarrhoea
  • Nausea
  • Skin rashes
  • Vomiting

Other less common side effects include –

  • Loss of appetite
  • Difficulty breathing
  • Eye infection
  • Mouth ulcers
  • Weight loss
  • Weakness

What Are The Effects of Gefitinib on Organs?

  • Gefitinib may cause or worsen liver and kidney diseases.
  • Gefitinib may damage the stomach and intestinal walls.

Are There Any Reported Allergic Reactions?

  • An allergic reaction to Gefitinib is very rare.
  • Symptoms of an allergy include severe rashes, itching, dizziness and difficulty in breathing.
  • Seek immediate medical attention in case of allergic reaction.

Drug Interactions to be careful about?

Before taking Gefitinib to inform your doctor if you are taking any of these medications

  • Blood thinners like warfarin
  • Proton pump inhibitors like ranitidine, cimetidine, omeprazole etc.
  • NSAIDs like Ibuprofen, naproxen etc
  • Corticosteroids like prednisolone

Shows Effects/Results In 

The time required for the onset of action and duration of effects of Gefitinib is not clinically established.


Storage  Requirements for Gefitinib

  • Store at room temperature (20-25°C) away from light and moisture.
  • Keep away from the reach of children and pets

Pro Tips When Taking Gefitinib

  • Inform your doctor if you are allergic to Gefitinib
  • Avoid use during pregnancy and breastfeeding
  • Take the medicine at about the same time every day

FAQs

Is Gefitinib addictive?

No, Gefitinib is not addictive.

 Can I have Gefitinib with alcohol?

No, it is not recommended to have Gefitinib with alcohol.

Any particular food item to be avoided?

No.

 Can I have Gefitinib when pregnant?

No, it is not recommended to have Gefitinib when pregnant.

Can I have Gefitinib when feeding a baby?

No, it is not recommended to have Gefitinib when feeding a baby.

Can I drive after taking  Gefitinib?

Yes, it is okay to drive after taking Gefitinib.

What happens if I overdose on Gefitinib?

Overdosage may lead to difficulty in breathing and fainting. Seek immediate medical attention.

What happens if I eat expired Gefitinib?

No major side effect is seen upon consumption of a single dose of expired Gefitinib however if you notice any severe side effects, immediately inform your doctor.

What happens if I miss a dose of Gefitinib?

If you miss a dose, take it as soon as you remember but if less than 12 hours are remaining before your next dose, then skip the missed dose.

Also Read: Lokit | Imol | Hepatoglobine

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