Guaifenesin: Uses, Dosage, Price, Side Effects, Precautions & More

What is Guaifenesin?

Guaifenesin is an expectorant (these are oral drugs that are supposed to enhance the clearance of mucus). Although the expectorant Guaifenesin is not typically known as a cough suppressant, it is significantly better than placebo in reducing acute viral cough and inhibits cough-reflex sensitivity in patients with upper respiratory tract infection.

NOTE: Although expectorants were once commonly prescribed, there is little or no objective evidence for their efficacy. Such drugs are often emetics that are given in sub-emetic doses on the basis that gastric irritation may stimulate an increase in mucus clearance via a reflex mechanism. However, there is no good evidence for this assumption. Lacking evidence for their efficacy, the FDA has removed most expectorants from the market in a review of over-the-counter drugs.
Manufactured By – Dr Reddy’s Laboratories Ltd

Buy & Get Minimum 20% Discount: Medlife New User Offer | Coupons For Netmeds

Uses of Guaifenesin

Guaifenesin is used to treat:

  • Cough
  • Congestion; caused by bronchitis, common cold and breathing illness.
Also Read: Gabapentin Uses | Heparin Uses

How does Guaifenesin work?

  • Guaifenesin is thought to act as an expectorant by reducing the viscosity of secretions in the trachea and bronchi.
  • It aids in the flow of respiratory tract secretions increasing the efficiency of the cough reflex and facilitate removal of the secretions.

How to take Guaifenesin?

  • Guaifenesin can be taken by mouth with or without food.
  • Do not chew or crush it. You can swallow it whole or can split it in half.
  • In case of liquid, measure correctly using measuring cap.
  • In case of powder packets, empty the content onto the tongue and swallow.
  • Drink plenty of fluids while taking this medication.

Guaifenesin Price In India

Specifics Guaifenesin Price
200 mg Strip of 10 Tablets Rs 100

Common Dosage for Guaifenesin

  • If taking Guaifenesin without prescription, use it exactly as directed on the label.
  • 200 to 400 mg orally every 4 hours, in the case of immediate release formulation.
  • 600 to 1200 mg orally every 12 hours, in the case of sustained release formulation.
Also Read: Methylphenidate Dosage | Methylprednisolone Dosage

When to avoid Guaifenesin?

  • There are no known drug interactions between Guaifenesin and any foods or medications.
  • Guaifenesin is an incredibly safe drug from a drug interaction risk perspective.
  • Although Guaifenesin has no known drug interactions, it should not be mixed with other over-the-counter cough and cold medications containing Guaifenesin, due to the risk of overdose, especially in children.
  • Guaifenesin is often combined with other medications such as dextromethorphan and pseudoephedrine. These medications have many drug interactions and require much more care when using them in combination with other medications.

Precautions when taking Guaifenesin

  • Do not give Guaifenesin to a child younger than 4 years old.
  • You should not use Guaifenesin if you are allergic to it.
  • Do not increase the dosage or take for longer than is recommended.
  • Guaifenesin is for temporary use only. Do not take this medication for more than 7 days.

Side Effects of Guaifenesin

Some reported side effects of Guaifenesin are:

  • Nausea
  • Vomiting
  • Headache
  • Rash
Other medicine Side Effect: Metoclopramide Side Effect

Effects on organs?

  • On stomach and intestine- side effects have included stomach upset and vomiting with higher than recommended doses.
  • On nerves- side effects have occasionally included dizziness and headache.
  • On skin- side effects have included rare reports of rash.

Storage Requirements for Guaifenesin

  • Keep it in a dry, air tight container.
  • Keep Guaifenesin away from direct heat or moisture.
  • Keep it out of reach of the children.

Pro Tips for taking Guaifenesin

  • Drink extra fluids to help loosen the congestion and lubricate your throat while you are taking this medication.
  • Do not open, crush or chew Guaifenesin delayed-release tablets because this may cause too much of the drug to be released at once.
  • Protect Guaifenesin liquid from light.


Is Guaifenesin addictive?

No, Guaifenesin is not addictive

Can I have Guaifenesin with alcohol?

Using dextromethorphan together with ethanol can increase nervous system side effects such as dizziness, drowsiness, and difficulty concentrating

Any particular food item to be avoided?

No particular food to be avoided until your doctor advises so.

Can I have Guaifenesin when pregnant?

Guaifenesin is only recommended for use during pregnancy when the benefit outweighs the risk.

Can I have Guaifenesin while feeding a baby?

Guaifenesin effects while breastfeeding is not known yet. Consult your doctor before taking this drug.

Can I drive after taking Guaifenesin?

No, Guaifenesin may impair your thinking and alertness.

What happens if I overdose on Guaifenesin?

Overdosing Guaifenesin is unlikely to produce toxic effects since its toxicity is low (among adults and not children). Very large doses may cause nausea and vomiting.

What happens if I eat expired Guaifenesin?

It is advised to not to take expired medicines.

What happens if I miss a dose of Guaifenesin?

Take the next dose of Guaifenesin at the scheduled time. Never take more than the dose for a missed one.

Also Read: Escitalopram | Etodolac | Fluoxetine
📢 Hungry for more deals? Visit CashKaro stores for best cashback deals & online products to save up to ₹15,000 per month. Download the app - Android & iOS to get free ₹25 bonus Cashback!
Previous articleFluoxetine: Uses, Dosage, Price, Side Effects, Precautions & More
Next articleAircel Dwindles; Stays afloat With Funds from Creditors and Saudi Telecom | CashKaro News Network


Please enter your comment!
Please enter your name here

four × four =