Lantus (Insulin Glargine Injection): Uses, Dosage, Price, Side Effects, Precautions & More

Lantus (Insulin Glargine Injection): Uses, Dosage, Price, Side Effects, Precautions & More

What is Lantus?

The active ingredient of Lantus insulin is insulin glargine which is a man-made insulin similar to human insulin and provides a low and steady rate of artificial insulin to body cells.

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Uses of Lantus

Lantus is a long-acting insulin used to treat type 1 and type 2 diabetic patients. Lantus insulin is available in injection form for subcutaneous use. It can be used in combination with other short-acting insulins and other oral hypoglycemic drugs

Also Read: Entresto Uses | Glipizide Uses

How does Lantus work?

  • Lantus (Insulin Glargine Injection) is a sterile solution of insulin glargine. Each ml of Lantus contains 100 international units of insulin glargine.
  • Insulin glargine is man-made insulin which works similar to human insulin and decreases the blood glucose levels by stimulating glucose uptake by muscles and by inhibiting the production of glucose by the liver.
  • By controlling the blood glucose levels, it decreases the incidence of kidney damage, heart problems, blindness, nerve problems etc.

How to Take Lantus?

  • The dose and duration of treatment with Lantus are based on your age, the severity of the condition, physical health, and response to therapy.
  • Lantus should not be injected while it is cold as it can be very painful. It is always recommended to inject it at room temperature.
  • Do not inject Lantus if the solution has become cloudy or has clumps in the container. Discard the container in such cases.
  • Before injecting, make sure the site is clean and dry. It is better to use it subcutaneously under the skin. Do not inject via the intravenous or intramuscular route.
  • Do not mix Lantus insulin with other insulin products and solutions.
  • Never re-use/share the same syringe or needle again as it might increase the chances of transmitting serious infections like hepatitis, HIV.
  • Non-pharmacologic therapy (dietary modification, weight control, and exercise) is equally essential to reduce blood glucose levels along with Lantus therapy.

Lantus Price In India

SpecificsLantus Price
100IU/ml Cartridge of 3 ml Solution for InjectionRs 597.2
Lantus Solostar: 100IU/ml Pen of 3 ml InjectionRs 1017.69
100IU/ml Vial of 10 ml InjectionRs 2938.01
Also Read: Krill-Oil Price

Common Dosage for Lantus?

  • There is no fixed dose regimen of Lantus (Insulin Glargine Injection) for the treatment of diabetes. Constant monitoring of blood glucose levels and dose variation accordingly is a must.
  • To reduce the risk of side effects, your doctor may initially start from a low dose and gradually increase your dose based on your condition.
  • Measure the dose carefully as the smallest change in insulin dose may have a large effect on blood sugar levels.
  • Lantus insulin is usually administered once a day at the same time every day.
  • Dose adjustment of Lantus insulin is needed with a change in physical activity, time and amount of food intake, change in kidney and liver functions.
Also Read: Humalog Dosage | Hydrocodone Dosage

When to Avoid Lantus?

Lantus (Insulin Glargine Injection) should be avoided or used with caution in:

  • Patients with allergy to any of its components
  • Diabetic ketoacidosis (a complication of diabetes associated with building up of acids)
  • Severe kidney or liver function disorders

Side-effects of Lantus?

In addition to its intended uses, Lantus may cause few undesirable side effects which may include:

  • Hypoglycemia – most commonly observed if patients take this medicine before meals or when patients skip their meals. Symptoms of hypoglycemia (low blood glucose) include:
  • Restlessness
  • Headache
  • Sleepiness
  • Impaired concentration
  • Depression
  • Confusion
  • Tremor
  • Dizziness
  • Palpitations
  • Tachycardia (increased heartbeat)
  • Anxiety
  • Fatigue
  • Sweating

Other less commonly observed side effects include:

  • Rash
  • Pain at the injection site
  • Dizziness
  • Difficulty in breathing
  • Hyperglycaemia – thirst, increased urination, confusion, fruity breath odor, rapid breathing etc.

In addition, it may cause some other allergic or unwanted effects. In such cases, seek medical attention immediately.


Effect on organs?

Liver & Kidney – Patients with pre-existing liver and kidney disease should use Lantus with caution as it can cause severe hepatic and renal impairment.


Reported Allergic Reactions?

Allergic reactions with Lantus (Insulin Glargine Injection) have been reported. Inform your doctor if you are allergic to any of its ingredients. Signs of allergic reaction include:

  • Rashes/itching of the skin
  • Shortness of breath
  • Swelling of face, lips, tongue, or throat
  • Loss of consciousness
  • Angioedema (painless swelling under the skin)

Drug Interactions to Be Careful About

Drug interactions refer to the effect of drugs on each other and on the human body after ingestion. There are large numbers of medicines which have shown to interact with each other. It is always advisable that the patient must inform the doctor about all the drugs/over the counter products/vitamin supplements used while using Lantus. All the possible drug interactions might not be listed here. Few important drugs which interact with Lantus (Insulin Glargine Injection) are listed below:

  • Alcohol
  • Glucagon
  • Beta-blockers
  • Clonidine
  • Sulfonamides
  • Diuretics
  • Oral contraceptives
  • Alcohol
  • Reserpine
  • Lithium

Using all these products along with Lantus (Insulin Glargine Injection) can influence the therapeutic effect of these medicines and also can increase the chances of side effects. Thus, dose alteration or drug replacement might be needed when Lantus is taken along with these drugs.


Shows Effects / Results In

Lantus starts showing its effect immediately following its subcutaneous administration and the effects may remain sustained up to 24 hours as it is a long-acting insulin.


FAQs

Is Lantus (Insulin Glargine Injection) addictive?

No habit forming tendency has been reported. However, over-dependence to these medicines should be avoided.

Can I have Lantus with alcohol?

  • Consumption of alcohol is not recommended when on Lantus therapy as it may interfere with controlling blood glucose levels.
  • It is best not to drink alcohol when on Lantus therapy. Consult your doctor for further recommendations.

Any particular food item to be avoided?

Avoid foods which have high glucose content and follow a strict diet to control blood glucose level along with Lantus (Insulin Glargine Injection) therapy.

Can I have Lantus when pregnant?

  • Lantus is not recommended during pregnancy as abnormal blood glucose levels during pregnancy are associated with higher incidence of congenital abnormalities.
  • Lantus should only be used if the benefits outweigh the risks involved.
  • Consult your doctor in case if you are pregnant or plan to become pregnant for case-specific recommendations.

Can I have Lantus when feeding a baby?

  • Lantus (Insulin Glargine Injection) is not recommended for use while you are breastfeeding as the drug may pass into breast milk and may harm the foetus by decreasing blood sugar levels.
  • Consult your doctor for case-specific recommendations.

Can I drive after taking Lantus (Insulin Glargine Injection)?

Lantus intake doesn’t affect your ability to drive. However hypoglycaemia caused due to overdosage or skipping meals and hyperglycaemia due to improper dosage may cause drowsiness, fatigue, impaired concentration, sleepiness etc which may hinder with driving and operating heavy machinery.

What happens if I overdose on Lantus?

  • Lantus should never be administered in more than prescribed dose.
  • Taking more medication or with increased frequency may cause serious Hypoglycaemia (symptoms of which have been mentioned above)
  • If suspected of an over-dosage, seek medical care immediately.

What happens if I take expired Lantus (Insulin Glargine Injection)?

  • A single dose of expired Lantus may not cause any major adverse effect. However, the potency of the medicine may well have decreased over time and it may cause hyperglycaemia (increased blood glucose levels).
  • Please inform your physician regarding the same if expired medicines have been taken chronically for a longer duration.

What happens if I miss a dose of Lantus?

  • The medicine may not work well if you miss a dose as it may lead to hyperglycaemia and poor glucose control.
  • If you forget to take a dose, take it as soon as you remember. But, if it’s already time to take the second dose – do not take a double dose.

Storage of Lantus (Insulin Glargine Injection)

  • Store at a cool and dry place away from direct heat and moisture.
  • Do not freeze the medicine.
  • Keep medicines away from children and pets.

Pro Tips When Taking Lantus (Insulin Glargine Injection)

Lantus should be administered along with non-pharmacologic therapy (proper dietary modification, weight control and exercise) to achieve the best results. In early type 2 diabetes, only non-pharmacologic therapy may well provide ideal results.


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