Lasix (Furosemide): Uses, Dosage, Side Effects, Precautions, Price & More

Lasix (Furosemide): Uses, Dosage, Side Effects, Precautions & More

What is Lasix?

  • Lasix belongs to a group of drugs called as “Loop Diuretics” which are used in the management of oedema and hypertension (high blood pressure).
  • Furosemide (Anthranilic acid derivative) acts as active ingredient of Lasix.
  • Lasix can be used in the prevention, control and treatment of following diseases:
  • Oedema associated with congestive heart failure
  • Oedema associated with cirrhosis of liver
  • Oedema associated with kidney disease (including nephritic syndrome)
  • Acute pulmonary oedema
  • Hypertension (high BP)
  • Lasix can also be used for purposes not mentioned above.
Check out Hindi translation of this article - Lasix in Hindi
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How does Lasix work?

  • Lasix (Furosemide) is a loop diuretic which acts on Proximal convulated tubule, distal convulated tubule and loop of henle structures in Kidneys and remove excess water and certain electrolytes from the body through urine.
  • By increasing the amount of urine that body makes, Lasix helps in reduction of oedema and hypertension.

Lasix Price in India

SpecificsLasix Price
40mg Strip of 15 TabletsRs 7.9

How to Take Lasix?

  • The dosage and duration of treatment with Lasix is based on your health status, severity of condition and initial response to the therapy.
  • Lasix is available in tablet form (20mg, 40mg and 80mg) and parenteral form (injection form) either IM (intramuscular) or IV (intravenous).
  • Food has a very slight effect on absorption of lasix, thus it can be taken with or without food or as advised.
  • For ideal results, it should always be taken at a fixed time. It is advisable not to take this medicine around bed time to prevent having to get up at night to urinate.
  • The tablet should be swallowed as a whole without crushing, chewing or breaking it along with plenty of fluids.
  • The medicine should not be stopped on your own without doctor’s consent or before the complete course.
  • If it is taken as over the counter product, check the label for directions before use.
  • Parenteral form (Injectable form) should only be used in patients who cannot take oral form of lasix and in emergency conditions.

Common Dosage for Lasix

  • Lasix (Furosemide) should always be administered in the dose and form as prescribed by your physician.
  • The initial recommended dose in adults is 20-80mg per day. If there is inadequate response, the dose can be increased in increment of 20-40mg not before 6-8 hours after the previous dose until the desired effect is achieved.
  • The final determined dose then can be given once or twice daily in adults.
  • In children, the dosage is usually calculated by the doctor based on weight of the child. Usual initial dose- 2mg/kg body weight per day. Doses greater than 6mg/kg body weight are not recommended in children.
  • In geriatric patients, lasix should be used cautiously, usually starting the dose at low end of dosing range.
  • Patients suffering from kidney disease or undergoing haemodialysis, the dosage might be reduced or altered as advised by your doctor.

In case if your condition does not improve or worsens, discontinue the drug and inform your doctor.

Also Read: Itraconazole Dosage | Intagesic MR Dosage | Ibugesic Plus Dosage

Precautions- When to Avoid Lasix

Lasix should be avoided or used with caution in:

  • Patients with allergy to any of its components
  • Patients with anuria (non-passage of urine)
  • Patients with urinary retention (prostate hyperplasia, urethral narrowing)
  • Pregnant and lactating females
  • Patients with hypoproteinemia (nephrotic syndrome)
  • Patients with kidney disease
  • Patients undergoing haemodialysis
  • Patients with electrolyte imbalance
  • Patients allergic to Sulfa drug

Side-effects of Lasix

  • GIT side effects
  • Nausea
  • Vomiting
  • Diarrhoea
  • Loss of appetite
  • Liver enlargement
  • Pancreatitis
  • Central nervous system side effects
  • Headache
  • Blurred vision
  • Hearing loss
  • Vertigo
  • Dizziness
  • Tinnitus(ringing in ears)
  • Paraesthesia (altered sesation)
  • Hematologic reactions
  • Anaemia (decreased RBC)
  • Leukopenia (decreased WBC)
  • Eosinophilia
  • Thrombocytopenia (decreased platelet count)
  • Dermatologic reaction
  • Rash
  • Photosensitivity (sensitivity to sunlight)
  • Pruritis (itching)
  • Urticaria
  • Stevens- Johnson syndrome
  • Erythema multiforme
  • Cardiovascular reactions
  • Orthostatic hypotension (low blood pressure which happens while standing up) – aggravated by alcohol, barbiturates.
  • Increase in cholesterol and triglycerides
  • Others
  • Hyperglycemia (increased blood glucose)
  • Glycosuria (excess of sugar in urine)
  • Urinary bladder spasm
  • Restlessness
  • Weakness
  • Fever
  • Muscle spasm
  • In addition it may cause some other allergic or unwanted effects. In such cases, seek medical attention immediately.

Effect on organs

  • Patients with severe kidney and liver disease should use Lasix (Furosemide) with caution and under supervision of a doctor.

Reported Allergic Reactions

  • Allergic reactions with Lasix have been reported. Inform your doctor if you are allergic to any of its ingredients.
  • Signs of allergic reaction include:
  • Rashes/itching of skin
  • Shortness of breath
  • Swelling of face, lips, tongue, or throat
  • Loss of consciousness

Drug Interactions to Be Careful About

  • Drug interactions refer to effect of drugs on each other and on human body after ingestion.
  • The patient must always inform the doctor about all the drugs/over the counter products/vitamin supplements used while using Lasix.
  • All the possible drug interactions might not be listed here. Few important drugs which interact with Lasix are listed below:
  • Aminoglycosides
  • Cisplatin
  • ACE inhibitors (blood pressure medicine)
  • Lithium
  • Phenytoin
  • Methotrexate
  • Sucralfate
  • Cyclosporine
  • Chloral hydrate
  • Using all these products along with Lasix increases the chances of side effects and also can affect the working of the drug.
  • Thus dose alteration or drug replacement might be needed when Lasix is taken along with these drugs.

Shows Effects / Results In:

  • The peak effect occurs within the first or second hour. The duration of diuretic effect is 6 to 8 hours.
Also Read: Ketoconazole Side Effect | Ketorol DT Side Effect | LCZ Side Effect

Storage of Lasix

  • Stored at cool and dry place away from direct heat and moisture.
  • Keep medicines away from children and pets

Pro Tips When Taking Lasix

  • Lasix (Furosemide) will make you urinate more often leading to dehydration and electrolyte imbalance in the body. Always use potassium supplements and keep yourself well hydrated while on Lasix therapy.
  • Using higher than recommended doses of Lasix may cause reversible or irreversible hearing impairment or deafness.
  • Furosemide in lasix may also increase blood glucose level in diabetic patients thereby affecting urine glucose tests.
Also read about other medicine's: Levolin syrup |i-Pill 

FAQ

Is Lasix addictive?

  • No habit forming tendency has been reported. However over dependence to these medicines should be avoided

Can I have Lasix (Furosemide) with alcohol?

  • Consumption of alcohol is not recommended when on Lasix therapy as it may increase the risk of adverse effects like dizziness, headache, light headedness, changes in heart rate and fainting (orthostatic hypotension).
  • It is best not to drink alcohol when on Lasix.

Any particular food item to be avoided?

  • No alteration in its action seen with any food product.

Can I have Lasix (Furosemide) when pregnant?

  • Furosemide has been shown to cause unexplained maternal deaths when administered in pregnant rabbits.
  • Therefore Lasix tablets may be unsafe to use during pregnancy.
  • Consult your doctor in case if you are pregnant or plan to become pregnant and are taking Lasix.

Can I have Lasix when feeding a baby?

  • Lasix (Furosemide) should be used with caution while you are breast feeding as the drug may pass into breast milk and my harm the foetus.
  • Consult your doctor for case specific recommendations.

Can I drive after taking Lasix?

  • Lasix intake is associated with a majority of CNS side effects like dizziness, sedation, decreased alertness, vertigo, blurred vision etc.
  • Therefore it may not be advisable to drive a vehicle and operate heavy machinery while on this medication if you experience these symptoms.

What happens if I overdose on Lasix (Furosemide)?

  • Lasix should never be administered in more than prescribed dose.
  • Overdosage on Lasix may show the following symptoms: dehydration, electrolyte imbalance, hypotension, hypokalemia (decreased potassium levels).
  • When suspected of an over-dosage, seek medical care immediately.

What happens if I take expired Lasix?

  • The potency of the expired medicine may well have decreased overtime. Expired medicine may also cause certain adverse effects.
  • Please inform your physician regarding the same if expired medicines have been taken chronically for a longer duration and refrain from using expired medicines.

What happens if I miss a dose of Lasix?

  • Lasix (Furosemide) is sometimes used only once a day. So chances of skipping a dose are less.
  • However, If you missed a dose, take it as soon as you remember. But, if it’s already time to take the second dose – do not take double the dose.

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