LATUDA: Benefits, Uses, Dosage & Side Effect

What is Latuda?

  • Latuda belongs to group of drugs called as “atypical antipsychotic drugs” which are used for mental disorders.
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Uses of Latuda:

  • Schizophrenia
  • Depressive episodes associated with bipolar disorder as mono-therapy or in combination with other drugs
Read more: Zocor Uses

Latuda Composition

Each 18.5mg film-coated tablet contains lurasidone hydrochloride equivalent to 18.6 mg lurasidone.

Know more: Kenalog Composition

How does Latuda work?

  • Dopamine acts as one of the most important neurotransmitter of the brain. Change in the dopamine activity can cause psychotic problems.
  • Latuda has selective action on dopamine receptors thus it acts by modulating the action of these neurotransmitters in brain.

How to Take Latuda?

  • Available as tablets in various strengths: 20mg, 40mg, 60mg, 80mg and 120mg.
  • The dosage and duration of Latuda intake should be decided by the doctor. Do not take more than or less than the recommended dose.
  • Latuda is well absorbed orally and should be administered with food usually once a day.
  • The tablet should be swallowed as a whole without crushing, chewing or breaking it along with plenty of fluids.
  • Latuda should not be stopped in between without doctor’s consent and before the course of the therapy is not completed.

Common Dosage for Latuda?

  • Dosage should initially be limited to smallest effective amount to decrease the severity of side effects. The dose can later be increased to get the best results.
  • The recommended starting dose of Latuda for schizophrenia patients is 40mg per day and the dose can be increased up to 160mg per day.
  • Recommended dose for bipolar disorder patients is 20-120mg per day.
  • In case of non-improvement of symptoms or symptoms getting worse, consult your doctor immediately.
Read more: Spiriva Dosage

When to Avoid Latuda?

  • Latuda should be avoided or used with caution in following patients:
  • Patients with allergy to any of its components
  • History of epilepsy
  • Pregnant and breast feeding women
  • Elderly patients with dementia
  • Patients with diabetes mellitus or dyslipidemia
  • Prolactin imbalance
  • Patients with severe kidney and liver disease
Read more: Mefloquine PrecautionNamenda Precaution

Side-effects of Latuda:

  • Common side effects with Latuda include:
  • Drowsiness
  • Postural hypotension (drop in blood pressure while standing)
  • Unusual tiredness and weakness
  • Dizziness
  • Irregular menstrual cycle
  • Weight gain
  • Movement disorder
  • Constipation
  • Decreased libido
  • Neuroleptic malignant syndrome (muscle rigidity and high fever)
  • Decrease in WBC count
  • Metabolic changes like hyperglycaemia (increase in blood glucose levels) and dyslipidemia.
  • In addition, it may also cause some allergic or unwanted effects. In such cases, seek medical attention immediately.
Know more: Novolog Side Effects

Effect on organs?

  • Patients with severe liver and kidney disease should use Latuda with caution. Dose adjustment might be needed in few cases.

Reported Allergic Reactions?

  • Report to your doctor if you are allergic to any of the ingredients of Latuda.
  • Signs of allergic reaction include:
  • Rashes/itching of skin
  • Shortness of breath
  • Swelling of face, lips, tongue, or throat
  • Loss of consciousness

Drug Interactions to Be Careful About

  • Large numbers of medicines have shown some interaction with another drug resulting in decreased therapeutic effect and increased chances of side effects.
  • It is always advised that the patient must inform the physician about all the drugs/over the counter products/vitamin supplements being used along with Latuda capsules.
  • All the possible drug interactions might not be listed here. Latuda may interact with the following drugs and products:
  • Alcohol
  • Rifampicin
  • Ketoconazole
  • Ritonavir
  • Clarithromycin
  • Phenytoin
  • Carbamazepine
  • Lithium
  • Valproate

Shows Effects / Results In:

  • The effects of Latuda start within 1-2 hours after oral administration and the effect lasts for around 5-8 hours.

Storage of Latuda

  • Stored at room temperature away from direct sunlight and heat.
  • Keep medicines away from children and pets.

Pro Tips When Taking Latuda:

  • Latuda should be used with caution in elderly patients with dementia as these patients are at increased risk of death due to increased incidence of cerebrovascular adverse events.
  • Patients on Latuda may suffer from postural hypotension (fall in blood pressure when person stands up from sitting or lying down).

Frequently asked questions

Is Latuda addictive?

  • No such tendency has been reported.

Can I have Latuda with alcohol?

  • Consumption of alcohol is not recommended when on Latuda therapy as it may increase the risk of adverse effects and may make you feel sleepy and dizzy along with alteration in blood pressure.

Any particular food item to be avoided?

  • It should not be administered with grape fruit or grape fruit juice.

Can I have Latuda when pregnant?

  • Usage of Latuda is not recommended during pregnancy. It should only be used if the benefits outweigh the risks involved.

Can I have Latuda when feeding a baby?

  • Nursing mothers are not recommended to use Latuda tablets as it may pass into breast milk and could harm the baby.

Can I drive after taking Latuda?

  • Few patients on Latuda may experience side effects like sedation, drowsiness, decreased blood pressure, confusion etc.
  • Caution must be exercised in such patients when driving or operating heavy machinery.

What happens if I overdose on Latuda?

  • It should not be administered in more than recommended dose as it may have deleterious effects.
  • Signs of over dosage include: excessive drowsiness, fall in blood pressure, agitation, coma etc.
  • If anyone is suspected of an over-dosage, seek medical care immediately.

What happens if I take expired Latuda ?

  • Taking a single expired dose may not cause any major adverse effect. However, the potency of the medicine may well have been reduced.
  • To be on the safer side, always check and never use an expired drug.

What happens if I miss a dose of Latuda ?

  • Always consume the missed dose as soon as you remember it. But, if it’s already time for the second dose– do not take double the dose.

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