Leflunomide: Uses, Dosage, Price, Side Effects, Precautions & More

What is Leflunomide?

Leflunomide is a medication which acts as an immune system suppressant drug.

Manufactured By – Sun Pharmaceutical Industries Ltd

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Uses of Leflunomide

Some of the common uses of Leflunomide are:

  • Rheumatoid arthritis
  • Psoriatic arthritis

How Does Leflunomide Work?

Leflunomide acts via suppressing the blood cells which are responsible for inflammation associated with autoimmune diseases.

How to Take Leflunomide?

Leflunomide tablet must be swallowed as a whole with a glass of water. You must not chew, crush or break the tablet while taking it. You may consume this medication on an empty or full stomach.

Leflunomide Price In India

SpecificsLeflunomide Price
20 mg Strip of 10 TabletsRs 271.25
Also Read: Cosentyx Price | Humulin Price

Common Dosage for Leflunomide?

Leflunomide is generally prescribed once or twice daily. Your doctor may alter your dosage and its frequency depending upon the severity of your condition.

When to Avoid Leflunomide?

Avoid Leflunomide if:

  • You are allergic to any component of Leflunomide
  • You have Peripheral Neuropathy
  • You have high blood pressure
  • You have kidney or liver impairment

Side-Effects of Leflunomide

Some of the reported side effects of Leflunomide are:

  • Nausea
  • Headache
  • Diarrhea
  • Airway infection
  • Cough
  • Dizziness
  • Sore throat
  • Chest pain
  • Severe stomach pain
  • Joint pain
  • Weight loss
  • Dry skin
Also Read: Xeljanz Side Effect

Effects of Leflunomide on Organs?

Long term use of Leflunomide is not safe for the patients with kidney and liver disease. Your doctor may adjust your dose as per your requirement.

Are There Any Reported Allergic Reactions?

Some of the common allergic reactions reported with Leflunomide are:

  • hives,
  • difficulty breathing,
  • and swelling of your face, lips, tongue, or throat.

Drug Interactions to Be Careful About

One needs to be careful about the following drug interactions with Leflunomide:

  • Warfarin
  • Aspirin
  • Ibuprofen
  • Chlorpropamide
  • Teriflunomide

Effects/Results After Consuming Leflunomide

The effect of Leflunomide can be observed within 1 to 2 hour of administration. Your disease symptoms will start to improve after taking this medication.

Things to Know About Leflunomide


Is Leflunomide addictive?

Leflunomide is not addictive in nature.

Can I have Leflunomide with alcohol?

It is better to avoid alcohol when on Leflunomide. Consult your doctor about limiting alcohol with this medication. Co-consumption of alcohol with Leflunomide causes excessive sleepiness and drowsiness.

Any particular food item to be avoided?

You must consult your doctor regarding the foods to be avoided.

Can I have Leflunomide when pregnant?

In most cases, it is not safe to take Leflunomide if you are pregnant or planning a pregnancy. Consult your doctor if it is absolutely necessary to take this medication.

Can I have Leflunomide when feeding a baby?

Leflunomide is known to pass in mother’s milk to the baby. Consult your doctor if it is absolutely necessary to take this medication while you are breastfeeding.

Can I drive after taking Leflunomide?

It is generally safe to drive while taking Leflunomide. However, if you experience drowsiness, dizziness, a headache or any side effect that alters your consciousness then it may not be safe to drive.

What happens if I overdose on Leflunomide?

An overdose of Leflunomide will not improve your symptoms. It may even cause serious side-effects like stomach pain, nausea, vomiting, and diarrhea. Consult your doctor immediately in case of overdose.

What happens if I eat expired Leflunomide?

If by mistake you consume a dose of expired Leflunomide, the chances of harm are very less. It is advised to check the label for expiry date always before use.

What happens if I miss a dose of Leflunomide?

As soon as you remember, take the missed dose. However, if it is already time for next dose, carry on with your regular schedule. Do not take a double dose to make up for the missed dose.

Storage Requirements for Leflunomide

  • Always store Leflunomide at a temperature around 25 degree Celsius
  • Storing in moisture-prone places like bathroom may damage the tablet
  • Keep Leflunomide away from direct heat and sunlight
  • Store it where your children and pets can’t reach

Pro Tips When Taking Leflunomide

  • Do not try to self-adjust the dose. Take it in the quantity prescribed by your doctor.
  • Do not share your medication with anyone even if they have a similar condition.
  • Discuss the pros and cons of Leflunomide if you are pregnant or planning a pregnancy or if you are breastfeeding.
  • You are at more risk of infections or falling sick while on this medication, so it is necessary to take precautions.
  • Your doctor must know your complete medical history before prescribing Leflunomide.
Other medicine's to read: Xifaxan | Zinc Sulphate | Zyprex
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