What is Lesuride?

Lesuride belongs to group of drugs called as “atypical antipsychotic drugs” which are used for mental disorders. Lesuride has antipsychotic, antidepressant, antiemetic (prevents vomiting) and anti dyspeptic (anti-indigestion) property.

Composition: Levosulpiride 25mg/75mg
Manufactured by – Sun Pharma Laboratories Ltd.
Prescription– Prescription needed
Form – Tablet
Price – Rs. 82
Type of Drug –
Atypical antipsychotic drugs

Read more: Naxdom Composition | Sizodon Composition

Uses of Lesuride

Lesuride can be used in the prevention, control and treatment of following diseases and symptoms:

  • Schizophrenia
  • Depression
  • Burning mouth syndrome
  • Premature ejaculation
  • Diabetic gastroparesis (condition affecting proper stomach emptying)
  • Anxiety disorder
  • Gastroesophageal reflex disease (heartburn, indigestion)
  • Irritable bowel syndrome
  • Lesuride can also be used for purposes not mentioned above.

How does Lesuride work?

  • Lesuride contains Levosulpiride as chief ingredient.
  • Dopamine acts as one of the most important neurotransmitter of the brain. Change in the dopamine activity can cause psychotic problems.
  • Levosulpiride has selective action on dopamine receptors thus it acts by modulating the action of these neurotransmitters in brain and specific regions of stomach and intestine.

How to Take Lesuride ?

  • Lesuride is available in the form of tablets and injection forms.
  • Lesuride is well absorbed orally and should be taken at least half an hour before food.
  • The tablet should be swallowed as a whole without crushing, chewing or breaking it along with plenty of fluids.
  • Lesuride should not be stopped in between without doctor’s consent and before the course of the therapy is not completed.
  • Lesuride should not be used as an over the counter drug. It is recommended to use this medicine under proper guidance.

Common Dosage for Lesuride

The drug dosage is decided by the physician based upon:

  • Health status/medical condition of the patient
  • Severity of symptoms
  • Reaction to the first dose
  • History of allergy/drug reactions
  • Dosage should initially be limited to smallest effective amount to decrease the severity of side effects. The dose can later be increased to get the best results.
  • The recommended dose for Lesuride for dyspepsia and other GI problems is 25mg tablets three times a day.
  • In elderly patients, dose reduction is necessary and the medicine should be taken strictly as advised by your doctor.
  • Do not change your dose or stop taking your medicine suddenly without your doctor’s consent.
  • In case of non-improvement of symptoms or symptoms getting worse, consult your doctor immediately.

Q. What happens if I overdose on Lesuride?

Lesuride should not be administered in more than prescribed dose. Taking increased dose will not improve your symptoms earlier; rather it may cause serious side-effects. Signs of over dosage include: excessive drowsiness, fall in blood pressure, agitation, coma etc.

In case of over dosage, consult your doctor immediately.

Q. What happens if I miss a dose of Lesuride?

The potency of the medicine may decrease because for effective working of the drug, a certain amount of drug must be present in your body at all times. Always consume the missed dose as soon as you remember. But, if it’s already time for the next dose – do not double the dose.

Q. What happens if I eat expired Lesuride?

The medicine may not work as well as the potency of the medicine gets affected. Please inform your physician regarding the same. To be on the safer side, always check and never use an expired medicine.

Q. What is the onset time of Lesuride?

The effects of Levosulpiride start within 1-2 hours after oral administration and the effect lasts for around 5-8 hours.

Q. Till when does the effect of Lesuride stay?

The duration of time for which the medicine remains effective is 5 to 8 hours.

Read more: Syndopa Plus Dosage

When to Avoid Lesuride?

Lesuride should not be used in the following conditions:

  • Allergy – if the patient is allergic to any of the components present in Lesuride.
  • History of epilepsy
  • Breast cancer
  • Alcohol intoxication
  • Tumours like phaeochromocytoma
  • Pregnant and breast feeding women
  • GIT (gastrointestinal tract) perforation
  • Prolactin imbalance
  • Heart diseases
  • Asthmatics
  • Patients with severe kidney and liver disease

Precautions While Taking Lesuride

Do not change your dose or stop taking your medicine suddenly without your doctor’s consent.

Read more: Urimax Precaution

Side-Effects of Lesuride

Majority of the patients do not show any side effects. Few patients might show side effects which include:

  • Drowsiness (common)
  • Postural hypotension (common)
  • Unusual tiredness and weakness (common)
  • Dizziness (common)
  • Irregular menstrual cycle (rare)
  • Weight gain (less common)
  • Breast tenderness (rare)
  • Constipation (less common)
  • Decreased libido (rare)
  • Neuroleptic malignant syndrome (muscle rigidity and high fever) – (rare)
  • Breast enlargement in males or Gynecomastia – (rare)

In addition, it may also cause some allergic or unwanted effects. In such cases, seek medical attention immediately.

Are There Any Reported Allergic Reactions to Lesuride?

Tell your doctor if you are allergic to any of its ingredients.

Signs and symptoms include:

  • Rash (common)
  • Itching (common)
  • Shortness of breath (less common)
  • Swelling of face, lips, tongue, or throat (rare)
  • Loss of consciousness (rare)

 What are the effects of Lesuride on organs?

Lesuride should be used cautiously in patients with severe liver and kidney disease. In such cases, dose adjustment as advised by the doctor may also be needed.

Drug Interactions to be Careful About

Drug interaction refers to effect of drugs on each other and on human body after ingestion. Large numbers of medicines have shown to interact with each other. Interactions are not just limited to drugs, but certain food items and some laboratory tests which should not be taken right after consuming Lesuride. We explore these in details below.

1. Food Interactions with Lesuride

No food interaction is noted with Lesuride.

2. Medicines Interactions with Lesuride

It is always advised that the patient must inform the physician about all the drugs/over the counter products/vitamin supplements used.It may interact with the following drugs and products:

  • Alcohol (mild)
  • Itraconazole – (severe)
  • Fluconazole – (severe)
  • Antacids (mild)
  • Antihypertensive medication (mild)
  • Tramadol – (severe)
  • Diazepam, Lorazepam – (severe)
  • Levadopa (moderate)
  • Cisapride (moderate)
  • Corticosteroids (moderate)
  • Furosemide (moderate)
  • Chloroquine (moderate)

3. Effects of Lesuride on Lab Tests

No effect on any lab tests noted while taking Lesuride.

4. Interactions with Pre-existing Conditions/Diseases

Patients suffering from pre-existing liver and kidney diseases must consult their physician before consuming Lesuride.

Q. Can I have Lesuride with alcohol?

Consumption of alcohol is not recommended when on Lesuride therapy as it may increase the risk of adverse effects and may make you feel sleepy and dizzy along with alteration in blood pressure.

Consult your doctor before consuming alcohol.

Q. Any particular food item to be avoided?

No food items have to be avoided while taking Lesuride tablets.

Q. Can I have Lesuride when pregnant?

There are no adequate and well controlled studies in pregnant women.  Always communicate with your doctor if you are pregnant or plan to become pregnant for case specific recommendations.

Q. Can I have Lesuride when feeding a baby?

Nursing mothers are advised to use Lesuride with caution as the drug may pass into breast milk and could harm the baby. Always inform your doctor before if you are breast-feeding your child.

Q. Can I drive after taking Lesuride?

Few patients on Lesuride may experience side effects like sedation, drowsiness, decreased blood pressure, confusion etc.

Caution must be exercised in such patients when driving or operating heavy machinery.

Lesuride  – Composition, Variant and Price– Buyer’s Guide

Lesuride Variants Lesuride Composition Lesuride Price (Rs.)
Lesuride घलरामूगदल 2ml Lesuride  Rs. 59.5
 Check out: Netmeds Offers | Medlife Offers | Pharmeasy Offers

Substitutes of Lesuride

The following are alternative drugs for Lesuride:

  • Ulpride OD
    • Manufactured by – Eris Lifesciences Pvt Ltd
    • Price – Rs. 151.25
  • Evopride Tablets
    • Manufactured by – Globus Labs
    • Price – Rs. 75
  • Tilpride Tablets
    • Manufactured by – Tablets India Ltd
    • Price – Rs. 45.08
Read more: Amixide H Price | Foracort Price

Storage requirements for Lesuride

  • Storage at room temperature away from direct light and heat unless mentioned in the package insert.
  • Keep medicines away from children and pets.

FAQs – 10 Important Questions Answered about Lesuride

Q. What is Lesuride?

Lesuride belongs to group of drugs called as “atypical antipsychotic drugs” which are used for mental disorders. Lesuride has antipsychotic, antidepressant, antiemetic (prevents vomiting) and anti dyspeptic (anti-indigestion) property.

Q. What are the uses of Lesuride?

It is used for mental disorders

Q. What are the side effects of Lesuride?

The most common side effects of Lesurideare Drowsiness, Postural hypotension, Unusual tiredness and weakness, Dizziness, Irregular menstrual cycle, Weight gain, Breast tenderness

Q. Should Lesuride be taken on an empty stomach?

Lesuride can be taken empty stomach.

Q. Does Lesuride make you drowsy?

No. It does not make you drowsy.

Q. What should be the time gap between the intakes of two Lesuride doses?

There should be a time gap of at least 8-12 hours between two doses of Lesuride.

Q. Should I complete the whole cycle of the medicine even if cured?

A complete course prescribed by your doctor must be taken for complete cessation of symptoms from your body.

Q. Does Lesuride effect my menstrual cycle?

No, Lesuride does not affect your menstrual cycle.

Q. Is Lesuride safe for children?

Lesuride is safe for consumption in children above 12 years of age. Children below 2 years should use it with caution.

Q. Are there any symptoms that I should consider before taking Lesuride?

Patients with history of allergy to Lesuride and its ingredients should not use it.

Q. Is Lesuride legal in India?

Yes, it is legal.

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Disclaimer – The information provided above is to the best of our research and knowledge. However, you are recommended to consult a physician before consuming the drug.

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