Levaquin (Levofloxacin): Uses, Dosage, Price, Side Effects, Precautions & More

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Levaquin (Levofloxacin): Uses, Dosage, Price, Side Effects, Precautions & More

What is Levaquin?

Levaquin is an antibiotic which is used to treat a different kind of bacterial infections. Levaquin is ineffective in treating viral infections like common cold, flu etc. The active ingredient of Levaquin is ‘Levofloxacin’ which belongs to “Quinolone” group of antibiotics.

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Uses of Levaquin

Levaquin (Levofloxacin) is commonly used in treatment or prevention of following diseases or symptoms:

  • Nosocomial pneumonia
  • Community-acquired pneumonia
  • Chronic bronchitis
  • Acute bacterial sinusitis
  • Complicated skin and skin structure infections
  • Chronic bacterial prostatitis (inflammation of prostate gland)
  • Urinary tract infections
  • Gynaecological infections
  • Acute pyelonephritis (inflammation of kidneys)

It may also be used for other purposes not mentioned above. Overuse or unnecessary usage of Levaquin may cause antibiotic resistance or decreased effectiveness of the antibiotic.

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How does Levaquin work?

  • Levaquin (Levofloxacin) belongs to “Quinolone” group of antibiotics which are considered to be bactericidal (bacterial killing ability).
  • It kills the bacteria by inhibiting the bacterial enzyme DNA Gyrase which further inhibits the synthesis of DNA (genetic material) and thus preventing its further multiplication.

How to Take Levaquin?

  • In order to reduce antibiotic resistance and increase the effectiveness of Levaquin, it is advisable that all antibacterial therapies including Levaquin should be selected based on bacterial culture and susceptibility tests.
  • A particular antibiotic should only be used to treat or prevent infections which are susceptible to it.
  • Levaquin (Levofloxacin) is available in different forms:
    • Tablets (250mg, 500mg, 750mg)
    • Syrup (25mg/ml)
    • Injection form
  • Dosage regimen should be adjusted according to individual patient needs, type of infection or as advised by the doctor.
  • Levaquin tablets are usually well absorbed orally and should be directly swallowed with water in one go without chewing or breaking it.
  • It is better to take Levaquin tablets/syrup on either an empty stomach or 1 hour before/ 2 hours after food.
  • For ideal results, it should always be taken at evenly spaced intervals to maintain a certain amount of drug in the body all the time.
  • In cases where syrup is used, shake the bottle well before each use to mix the medication evenly. Use a measuring cup to consume the correct dosage of medicine.
  • When on Levaquin therapy, it is always advised that medication should not be left in between without completing the full course as it:
  • Might decrease the efficacy of the drug and
  • Increase the likelihood of bacterial resistance to this drug thereby making it inefficient for future use.

Levaquin Price In India

SpecificsLevaquin Price
250 mg Strip of 10 TabletsRs 46.00
500 mg Strip of 10 TabletsRs 87.00
750 mg Strip of 10 TabletsRs 65.00
500 mg 100 ml INFRs 107.27
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Common Dosage for Levaquin

  • The dose of Levaquin varies with different bacterial infections:
    • Nosocomial pneumonia – 750mg in a day for 7-14 days
    • Community-acquired pneumonia – 500mg in a day for 7-14 days
    • Acute bacterial sinusitis – 500mg in a day for 10-14 days
    • Skin and skin structure infections – 750mg in a day for 7-14 days
    • Complicated urinary tract infections – 750mg in a day for 5 days
    • Acute exacerbation of chronic bronchitis – 500mg in a day for 7 days
    • Chronic bacterial prostatitis – 500mg in a day for 28 days
  • In patients suffering from kidney problems or on dialysis, the dosage of Levaquin may need to be altered.
  • Never use more than the recommended dose or for longer periods of time without doctor’s consent.
  • In case of non-improvement of symptoms or symptoms getting worse, seek medical attention immediately.
  • If taken as an over-the-counter product, read all directions on the product package before taking this medication.

When to Avoid Levaquin (Levofloxacin)?

Levaquin should not be used with:

  • If you are allergic to Levaquin
  • If you are allergic to drugs belonging to quinolone family like Levofloxacin, Ofloxacin, Gatifloxacin etc
  • Patients having a history of a tendon problem
  • Patients having myasthenia gravis (abnormal weakness of muscles)
  • Patients with a heart problem or long QT interval (heart’s electrical cycle)
  • Patients suffering from kidney disease or on dialysis
  • Patients suffering from liver diseases

Side-effects of Levaquin (Levofloxacin)?

Side effects are possible but do not always occur in all the patients. More commonly observed side effects may include:

  • Nausea
  • Vomiting
  • Indigestion
  • Diarrhoea
  • Dizziness
  • Headache
  • Altered taste sensation
  • Skin rash
  • In very few cases, patients might complain of some serious side effects like:
    • Signs of tendonitis, tendon rupture: pain, swelling, stiffness around joints
    • Prolongation of QT interval (heart’s electrical cycle)
    • Phototoxicity (susceptibility of skin to light)
    • Central nervous system effects like nervousness, depression, confusion
    • Nerve symptoms: numbness, burning sensation, tingling
    • Seizures
    • Allergic reactions

In such cases, tell your doctor immediately and seek immediate medical attention.

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Reported Allergic Reactions?

Although Levaquin (Levofloxacin) is used to treat bacterial infections an allergic reaction to Levaquin is possible. Signs and symptoms of possible allergic reactions include:

  • Itchy skin/rashes
  • Swelling especially on face, lips & throat
  • Difficulty in breathing or swallowing and
  • Loss of consciousness.

Effect on organs?

  • Dose adjustment is needed in patients suffering from kidney and liver diseases. In such patients, Levaquin should be administered with caution.
  • Levaquin use is associated with increased risk of tendonitis and tendon rupture in all age groups. The risk is further increased in people above 60 years of age and patients taking corticosteroids.

Drug Interactions to Be Careful About?

All the possible drug interactions might not be listed here. You must always inform the physician of all the drugs/over the counter supplements used. It is always better to inform your doctor if you are currently using any other drugs that make you drowsy or sleepy, such as sleeping pills, other allergy drugs, muscle relaxants, and drugs used for fits, depression, or anti-anxiety drugs. Some of the common drugs which interact with Levaquin (Levofloxacin) include:

  • Theophylline
  • Antacids
  • Nitrofurantoin
  • Warfarin
  • Digoxin
  • Tizanidine
  • Phenytoin
  • Clozapine
  • Cyclosporine

Using all these medicines along with Levaquin can increase the chances of side effects and can also influence the therapeutic effect of these medicines.


Shows Effects / Results In?

  • The time taken for Levaquin (Levofloxacin) to show its effect depends upon the form of medicine being consumed and its intended use.
  • Some patients might show the decreased severity of symptoms from day one but even if the symptoms have disappeared, the course of the medicine should always be completed.

FAQs

Is Levaquin Addictive?

No such tendency has been reported.

Can I have Levaquin (Levofloxacin) with alcohol?

The interaction of alcohol with Levaquin is not clear. Consult your doctor before consumption.

Any particular food item to be avoided?

  • Avoid taking dairy products and caffeine along with Levaquin. Keep a gap of at least 2 hours.
  • Take this medication at least 2 hours before or 2 hours after eating magnesium/ aluminium antacids.
  • Patients receiving Levaquin (Levofloxacin) should remain adequately hydrated to prevent the formation of highly concentrated urine.

Can I have Levaquin When Pregnant?

Levaquin is not suitable for use in pregnancy. Animal studies have shown adverse effects on fetus thus Levaquin should only be taken during pregnancy if the benefits outweigh the risks involved and following consultation with a doctor.

Can I have Levaquin when feeding a baby?

  • Always inform your doctor if you are breastfeeding your child.
  • Levaquin (Levofloxacin) is excreted in human milk so it should be avoided in lactating mothers.

Can I drive after taking Levaquin?

Levaquin Tablet usually does not affect your ability to drive. However, few patients might experience dizziness, decreased alertness as a side effect, in such cases, it should be used with caution while driving and operating heavy machinery.

What happens if I overdose on Levaquin (Levofloxacin)?

  • Levaquin should not be administered in more than prescribed dose.
  • Taking more medication or with increased frequency will not improve your symptoms early; rather they may cause serious side-effects.
  • In case of overdosage, consult your doctor immediately.

What happens if I eat expired Levaquin?

  • It is very unlikely for a single dose of expired Levaquin (Levofloxacin) to produce an adverse event. However, please consult your physician if you feel unwell or sick after consuming an expired medicine.
  • An expired drug might not be as potent in treating your condition. It is advisable to refrain from using an expired drug.

What happens if I miss a dose of Levaquin (Levofloxacin)?

  • The medicine may not work well if you miss a dose because, for effective working of the drug, a certain amount of drug must be present in your body at all times.
  • Always consume the missed dose as soon as you remember it. But, if it is already time to take the second dose after that – do not take a double dose.

Storage Requirements for Levaquin

  • Store it away from direct heat and light.
  • Keep the medicine away from children and pet

Pro Tips When Taking Levaquin (Levofloxacin)

Even if you begin to feel better in a few days of treatment with Levaquin, it is advisable that you complete the entire course of treatment. If the medicine is stopped in between, the symptoms might return or may get worsened. Also, chances of bacterial resistance to the drug may increase.


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