Levosulpiride: Uses, Dosage, Side Effects, Precautions, Price & More

Prescription – Required
Form – Tablet
Price – Rs.75 per strip of 10 tablets

What is Levosulpiride?

Levosulpiride belongs to a group of drugs called “atypical antipsychotic drugs” which are used for mental disorders. Levosulpiride has antipsychotic, antidepressant, antiemetic (prevents vomiting) and anti dyspeptic (anti-indigestion) property.

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Uses of Levosulpiride

Levosulpiride can be used in the prevention, control, and treatment of the following diseases and symptoms:

  • Schizophrenia
  • Depression
  • Burning mouth syndrome
  • Premature ejaculation
  • Diabetic gastroparesis (a condition affecting proper stomach emptying)
  • Anxiety disorder
  • Gastroesophageal reflex disease (heartburn, indigestion)
  • Irritable bowel syndrome

Levosulpiride can also be used for purposes not mentioned above.

How does Levosulpiride work?

  • Dopamine acts as one of the most important neurotransmitters in the brain. Change in the dopamine activity can cause psychotic problems.
  • Levosulpiride has a selective action on dopamine receptors thus it acts by modulating the action of these neurotransmitters in the brain and specific regions of stomach and intestine.

Levosulpiride Price in India

1*10 stripRs 75

How to Take Levosulpiride?

  • The dosage and duration of Levosulpiride intake should be decided by the doctor. Do not take more than or less than the recommended dose.
  • Levosulpiride is well absorbed orally and should be taken at least half an hour before food.
  • The tablet should be swallowed as a whole without crushing, chewing or breaking it along with plenty of fluids.
  • Levosulpiride should not be stopped in between without a doctor’s consent and before the course of the therapy is not completed.
  • Levosulpiride should not be used as an over the counter drug. It is recommended to use this medicine under proper guidance.

Common Dosage for Levosulpiride?

  • The optimum dosage of Levosulpiride varies with the condition of the patient, age of the patient and the initial response to the drug.
  • Dosage should initially be limited to the smallest effective amount to decrease the severity of side effects. The dose can later be increased to get the best results.
  • The recommended dose for Levosulpiride for dyspepsia and other GI problems is 25mg tablets three times a day.
  • In elderly patients, dose reduction is necessary and the medicine should be taken strictly as advised by your doctor.
  • Do not change your dose or stop taking your medicine suddenly without your doctor’s consent.
  • In the case of non-improvement of symptoms or symptoms getting worse, consult your doctor immediately.
Also Read: Librax Dosage | Lanol-ER Dosage

When to Avoid Levosulpiride?

Levosulpiride should be avoided or used with caution in following patients:

  • Patients with allergy to any of its components
  • History of epilepsy
  • Breast cancer
  • Alcohol intoxication
  • Tumours like phaeochromocytoma
  • Pregnant and breastfeeding women
  • GIT (gastrointestinal tract) perforation
  • Prolactin imbalance
  • Heart diseases
  • Asthmatics
  • Patients with severe kidney and liver disease

Also check: Medlife Coupon Code for New Users

Side-effects of Levosulpiride

Common side effects with Levosulpiride include:

  • Drowsiness
  • Postural hypotension
  • Unusual tiredness and weakness
  • Dizziness
  • Irregular menstrual cycle
  • Weight gain
  • Breast tenderness
  • Constipation
  • Decreased libido
  • Neuroleptic malignant syndrome (muscle rigidity and high fever)
  • Breast enlargement in males or Gynecomastia

In addition, Levosulpiride may also cause some allergic or unwanted effects. In such cases, seek medical attention immediately.

Also Read: Mannitol Side Effect | Maxtra Syrup Side Effect | Mebex Side Effect

What Are The Effects of Levosulpiride on Organs?

Patients with severe liver and kidney disease should use Levosulpiride with caution. Dose adjustment might be needed in a few cases.

Are There Any Reported Allergic Reactions?

Report to your doctor if you are allergic to any of the ingredients of Levosulpiride. Signs of allergic reaction include:

  • Rashes/itching of the skin
  • Shortness of breath
  • Swelling of face, lips, tongue, or throat
  • Loss of consciousness

Drug Interactions to Be Careful About

Drug interactions refer to the effect of drugs on each other and on the human body after ingestion. Large numbers of medicines have shown some interaction with another drug resulting in decreased therapeutic effect and increased chances of side effects. It is always advised that the patient must inform the physician about all the drugs/over the counter products/vitamin supplements being used along with Levosulpiride capsules. Levosulpiride can possibly interact with the following drugs:

  • Alcohol
  • Antacids
  • Antihypertensive medication (medicines which decrease blood pressure)
  • Levodopa
  • Cisapride
  • Corticosteroids
  • Furosemide
  • Chloroquine

Shows Effects / Results In

The effects of Levosulpiride start within 1-2 hours after oral administration and the effect lasts for around 5-8 hours.


Is Levosulpiride addictive?

No such tendency has been reported.

Can I have Levosulpiride with alcohol?

  • Consumption of alcohol is not recommended when on Levosulpiride therapy as it may increase the risk of adverse effects and may make you feel sleepy and dizzy along with an alteration in blood pressure.
  • Consult your doctor before consuming alcohol.

Any particular food item to be avoided?

No such interaction with food products seen.

Can I have Levosulpiride when pregnant?

  • Usage of Levosulpiride is not recommended during pregnancy. It should only be used if the benefits outweigh the risks involved.
  • Always communicate with your doctor if you are pregnant or plan to become pregnant for case-specific recommendations.

Can I have Levosulpiride when feeding a baby?

  • Nursing mothers are not recommended to use Levosulpiride tablets as it may pass into breast milk and could harm the baby.
  • Always inform your doctor before if you are breastfeeding your child.

Can I drive after taking Levosulpiride?

  • Few patients on Levosulpiride may experience side effects like sedation, drowsiness, decreased blood pressure, confusion etc.
  • Caution must be exercised in such patients when driving or operating heavy machinery.

What happens if I overdose on Levosulpiride?

  • It should not be administered in more than recommended dose as it may have deleterious effects.
  • Signs of overdosage include excessive drowsiness, fall in blood pressure, agitation, coma etc.
  • If anyone is suspected of an over-dosage, seek medical care immediately.

What happens if I take expired Levosulpiride?

  • Taking a single expired dose may not cause any major adverse effect. However, the potency of the medicine may well have been reduced.
  • To be on the safer side, always check and never use an expired drug.

What happens if I miss a dose of Levosulpiride?

Always consume the missed dose as soon as you remember it. But, if it’s already time for the second dose- do not take double the dose.

Storage Requirements for Levosulpiride

  • Stored at room temperature away from direct sunlight and heat.
  • Keep medicines away from children and pets.

Pro Tips When Taking Levosulpiride

  • Levosulpiride should be used with caution in heart patients and patients with gastrointestinal bleeding.
  • Patients on levosulpiride may suffer from postural hypotension (fall in blood pressure when a person stands up from sitting or lying down).
Also read about other medicine's: Livogen | Lyserd
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