Mecobalamin: Uses, Dosage, Side Effects, Price, Composition, Precautions & More

What is Mecobalamin?

  • Mecobalamin is a nutrient supplement used to treat vitamin B12 deficiency. Lack of Vitamin B12 can cause anaemia and nerve damage.
  • The primary ingredient of Mecobalamin is “Methylcobalamin” which is the active and potent form of vitamin B12.
  • Mecobalamin is available in two forms:
  • Tablet
  • Injection
Save using: Pharmeasy Promo CodeMyra Medicines Promo Code

Uses of Mecobalamin

  • Megaloblastic anaemia (deficiency of folic acid and vitamin B12)
  • Pernicious anaemia
  • Peripheral neuropathy (numbness and pain due to nerve damage especially of hands and feet)
  • Diabetic neuropathy
  • Alcoholic neuropathy
Know more: Klacid Uses

How does Mecobalamin work?

  • Methylcobalamin, the primary ingredient of Mecobalamin is necessary for production and maturation of red blood cells.
  • It also helps in normal protein synthesis and protects the integrity of nerve cells and encourages their normal growth.
  • Thus lack of Vitamin B12 can cause anaemia (due to lack of/defective RBC production and maturation) and neuropathy (nerve damage).
Read more: Famotin Composition

How to Take Mecobalamin?

  • When taken in tablet form, Mecobalamin is well absorbed orally and may be taken with or without food or as advised. For patients with gastric problems, it is better to take it after food.
  • Mecobalamin tablets and vials are susceptible to photolysis. Light decreases the content of methylcobalamin. Thus Mecobalamin tablets and vials should not be exposed to direct light and should be used immediately after.

Common Dosage for Mecobalamin?

  • The usual recommended dosage for adults is 3 tablets (1500mcg of Vitamin B12) daily divided into three doses.
  • When given in injection form, the usual dose for adults – 1 ampule (500mcg of vitamin B12) daily administered IM or IV three times a week.
  • Mecobalamin should not be used aimlessly for more than one month if it is not effective in alleviating symptoms.
Read more: Decolgen Dosage

When to Avoid Mecobalamin?

Mecobalamin should be avoided or used with caution in:

  • Patients with allergy to Methylcobalamin
Know more: Fybogel Precaution | Lopamide Precaution

Side-effects of Mecobalamin?

  • Majority of the patients do not show any side effects with methylcobalamin therapy. However, few patients reported  side effects include:
  • Nausea
  • Vomiting
  • Diarrhoea
  • Loss of appetite
  • Itching/rash
  • Headache
  • In addition it may cause some other allergic or unwanted effects. In such cases, seek medical attention immediately.

Effect on organs?

  • No adverse effects reported on any organs.

Reported Allergic Reactions?

  • Report to your doctor if you are allergic to any of its ingredients.
  • Signs of allergic reaction include:
  • Rashes/itching of skin
  • Shortness of breath
  • Swelling of face, lips, tongue, or throat
  • Decrease in blood pressure
  • Loss of consciousness

Drug Interactions to Be Careful About

  • All the possible drug interactions might not be listed here. It is always advised that the patient must inform the physician about all the drugs/over the counter products/vitamin supplements being used.
  • Mecobalamin may interact with the following drugs and products:
  • Alcohol
  • Omeprazole
  • Neomycin
  • Colchicines
  • Chloramphenicol
  • Ranitidine

Shows Effects / Results In:

  • The peak effect of Mecobalamin can be achieved after 3 hours of oral administration.

Storage of Mecobalamin

  • Storage at room temperature away from direct sunlight and heat as it is sensitive to photolysis.
  • Keep medicines away from children and pets.

Pro Tips When Taking Mecobalamin

  • The dosage/frequency of uptake of Mecobalamin may increase in severe alcoholics as alcohol interferes with absorption of vitamin B12.
  • In cases of pernicious and megaloblastic anaemia where Vitamin B12 is deficient, folic acid therapy has to be supplemented with Vitamin B12 therapy for proper treatment.
Also check out: Jointace Dn Price

Frequently asked questions

Is Mecobalamin addictive?

  • No

Can I have Mecobalamin with alcohol?

  • Consumption of alcohol is not recommended when on Mecobalamin therapy as it may interfere with absorption of vitamin B12 from intestine

Any particular food item to be avoided?

  • No alteration in its action seen with any food product.

Can I have Mecobalamin when pregnant?

  • Mecobalamin can be administered in pregnant ladies if the benefits outweigh the risks.

Can I have Mecobalamin when feeding a baby?

  • Mecobalamin is safe to administer in lactating women.

Can I drive after taking Mecobalamin?

  • Mecobalamin doesn’t affect one’s ability to drive. However, if someone experiences side effects like headache or dizziness then it may not be advisable to drive a vehicle and operate heavy machinery while on this medication.

What happens if I overdose on Mecobalamin?

  • It should not be administered in more than prescribed dose. Taking more medication or with increased frequency will not improve your symptoms faster.

What happens if I take expired Mecobalamin?

  • Taking a single expired dose may not cause any major adverse effect. However, the potency of the medicine reduces after expiry date.

What happens if I miss a dose of Mecobalamin?

  • Always consume the missed dose as soon as you remember it. But, if it’s already time to take the second dose after that – do not take double dose.

Similar Reads

📢 Hungry for more deals? Visit CashKaro stores for best cashback deals & online products to save up to ₹15,000 per month. Download the app - Android & iOS to get free ₹25 bonus Cashback!


Please enter your comment!
Please enter your name here

19 − 10 =