Melatonin: Uses, Dosage, Price, Side Effects, Precautions & More

Melatonin Composition – Not Available
Manufactured By – Guardian Healthcare Services Pvt Ltd
Prescription – Prescription Required
Form – Tablet
Price – Rs 2149
Quantity – 120 tablets in 1 bottle

What is Melatonin?

Melatonin is a pineal hormone. It is serotegenic (affecting serotonin). Melatonin induces pigment lightening in skin cells and suppresses ovarian functions; it also serves a role in regulating biological rhythms and shows promise in the treatment of jet lag and other sleep disturbances. It is secreted predominantly at night in both day- and night-active. Exogenous Melatonin increases sleepiness and may potentiate sleep when administered to good sleepers attempting to sleep during daylight hours at a time when endogenous Melatonin levels are low.
Other variants and compositions

Gnc Melatonin 3Mg Tr 60S Tablet / 120S3mg Melatonin + Vitamin B6
Buy & Get Minimum 20% Discount: 1mg | Netmeds | Myra Medicines

Uses of Melatonin

Melatonin is used to:

  • help decrease jet lag
  • adjust sleep cycles in the blind (non24-Hour Sleep Wake Disorder, or Non-24)
  • treat shift-work sleep disorders in people with alternating work schedules
  • for general insomnias
Also Read: Methadone Uses

How does Melatonin work?

  • Natural melatonin is a hormone produced in the pineal gland in the brain.
  • It is produced from the amino acid tryptophan and is then released into the blood and cerebrospinal fluid.
  • It sends messages to the melatonin receptor agonist in the brain and other areas of the body to help control the sleep and wake cycles.
  • When taken as a supplement (artificial melatonin), it mimics the work of natural melatonin.

How to take Melatonin?

  • Melatonin comes in different forms like in liquid form or capsules or tablets.
  • Take Melatonin at the correct time. If you take it for trouble in sleeping then controlled release formulation should be taken before going to bed.
  • In the case of the sublingual form, which will directly go into the bloodstream or liquid form, you may take it about 30 minutes before going to bed.

Melatonin Price In India

SpecificsMelatonin Price
3 mg Bottle of 180 CapsulesRs 1049
GNC Melatonin: Bottle of 60 Tablets Pack of 2Rs 2549
GNC Melatonin: Bottle of 60 TabletsRs 1304
GNC Melatonin: 3 mg Bottle of 120 TabletsRs 1611
Natures Velvet Lifecare GNC Melatonin: 3 mg CapsulesRs 559

Common Dosage for Melatonin

  • Generally available in 0.3 to 5 mg doses
  • A small dose to aid in falling asleep may work better than a larger one.
  • To ensure sleeping through the whole night, try taking a time-released dose of 0.3 to 5 mg.

When to avoid Melatonin?

  • Sedatives should be avoided with Melatonin.
  • Blood-thinner medications (anticoagulants) such as warfarin, heparin, or aspirin are to be avoided.
  • Medications for diabetes; blood sugar may increase with Melatonin.
  • Caffeine makes you stay awake, thus should not be taken with Melatonin.
  • Nifedipine

Other drugs interactions exist. Check with your doctor before you take Melatonin with any medication.

Precautions when taking Melatonin

  • Do not use Melatonin if you are allergic to it.
  • Before taking Melatonin, let your doctor know about any disease or health problems like diabetes, depression, high or low blood pressure.
  • Usage of sedatives or tranquilizers should also be reported to a doctor before using Melatonin.
  • High doses may affect ovulation.

Side Effects of Melatonin

Some of the commonly reported side effects of Melatonin are:

  • daytime drowsiness
  • depressed mood
  • stomach pain
  • headache
  • dizziness
Also Read: Bisoprolol Side Effect

Effect on organs?

There are not many effects of Melatonin on organs other than:

  • Cardiovascular effects – causes a drop in body temperature, presumably by affecting blood vessel diameters (dilation of blood vessels allows heat loss)
  • Sexual Maturation- melatonin decreases the function of the gonads (the testes and the ovaries) by decreasing the stimulation of these organs by the brain causing lower sex hormone levels.

Storage Requirements for Melatonin

  • Keep Melatonin in a dry, airtight container.
  • Keep it away from direct heat or moisture.
  • Keep it out of reach of the children.

Pro Tips When Taking Melatonin

  • Short-term use (less than 3 months) is relatively safe with little evidence of toxicity.
  • Lower dose and orally-dissolvable products for children are available.
  • Higher doses (2 to 10 mg) used for a long period may lead to rebound insomnia.


Is Melatonin addictive?

No, and Melatonin does not cause withdrawal symptoms, unlike other medications.

Can I have Melatonin with alcohol?

No, Melatonin will lose its effectiveness and cause dizziness and the person may faint.

Any particular food item to be avoided?

Avoid food which does not induce sleep like caffeine, spicy food, food high in protein and fat.

Can I have Melatonin when pregnant?

No, it is not recommended.

Can I have Melatonin when feeding a baby?

No, Melatonin may harm the development of the baby.

Can I drive after taking Melatonin?

No, it is harmful.

What happens if I overdose on Melatonin?

Overdosing on Melatonin may cause anxiety, headaches.

What happens if I eat expired Melatonin?

It is advised to not to take expired medicines.

What happens if I miss a dose of Melatonin?

Take the next dose at the scheduled time. Never take more than the dose for a missed one.

Also read about other medicine's: Dulcolax | Enalapril

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