Metformin: Uses, Dosage, Price, Side Effects, Precautions & More

What is Metformin?

Metformin is used under the trade name Glucophage. It is popularly known as a medication for Type II Diabetes which is caused due to high blood pressure and being overweight. Metformin should be taken along with a proper diet.

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Uses of Metformin

  • Metformin is used to treat polycystic ovary syndrome (PCOS)
  • Shreds of evidence are there that Metformin has been used to prevent cardiovascular diseases like heart attack and stole along with cancer.
  • It is used to prevent kidney damage and blindness.
  • Metformin is responsible for the prevention of loss of limbs and sexual functioning problems.
Also Read: Lisinopril Uses | Lomotil Uses | Loratadine Uses

How Does Metformin Work?

Metformin helps to restore the insulin’s response that pancreas produce which is absorbed by the stomach or intestine. It increases the muscle cells’ sensitivity to insulin.


How to Take Metformin?

  • During the first few weeks, Metformin should be taken with meals to reduce stomach-related side effect.
  • Swallow the drug wholly. Do not crush, break or chew the tablet.
  • The liquid form should be measured correctly before taking orally.

Metformin Price in India

Specifics Metformin Price
Metformin (A box) Rupees 470.00

Common Dosage for Metformin

  • The dosage is different for different people. So it is safe to consult the doctor before taking the dosage.
  • For Type II Diabetes and Children – dosage prescribed by the doctor.
  • Adults – Metformin alone is taken up to 2500 mg per day. But the normal is 1000 mg for one day. Metformin with insulin can be taken up to 500mg per day. Metformin along with sulfonylurea should have a dose which is determined by a doctor.
  • As in liquid form, Metformin along with insulin can be taken up to 5 ml per day but should not exceed above 25ml. Same with sulfonylurea should be consulted with a doctor beforehand.
  • Metformin alone should be taken up to 5 ml twice a day.
Other medicine's Dosage: Meloxicam Dosage | Mirtazapine Dosage

Precautions – When to Avoid Metformin?

While taking Metformin you should follow the following steps:

  • Don’t delay or miss a scheduled meal or snack
  • Don’t do excessive exercise
  • Don’t take Metformin along with other diabetes or certain medications.
  • Avoid the drug if you feel nausea and vomiting as that prevents you from taking your meal on time

Side-Effects of Metformin

Some common side effects of Metformin are:

  • Hypoglycaemia (Low Blood Glucose level)
  • Asthenia (Physical weakness)
  • Diarrhoea
  • Flatulence (Gastric problem)
  • Myalgia (Muscle pain)
  • Weakness
  • Respiratory tract infection (Upper tract)
  • Abdominal or stomach pain
  • Headache
  • Nausea
  • Vomiting
  • Lactic acidosis
  • Constipation
  • Weight loss
  • Constipation
  • Sometimes heartburn and bloating may occur

Effects of Metformin on Organs

As Metformin is used for fatty liver problem, it doesn’t really cause any damage to the liver. But it causes lactic acidosis to the patients who are diagnosed with high cirrhosis which can be harmful to both liver and kidney.


Drug Interactions to be Careful About

Drug interaction varies according to how the drug works. Avoid taking:

  • Acetazolamide,
  • Topiramate,
  • Gemifloxacin,
  • Moxifloxacin,
  • Ciprofloxacin

as they cause harmful effects on the body when allowed to interact with Metformin. It is always better to consult your doctor before taking any medications while you are taking Metformin.


Effects/Results after Consuming Metformin

Metformin may show its effect on controlling glucose within 1 or 2 weeks. But the full recovery will happen after 2 or 3 months which also may differ among people according to their weight, lifestyle, diet, etc.


Storage Requirements about Metformin

Metformin can be stored in a closed container at room temperature away from heat, moisture, and direct light. Also, keep it from freezing.


Pro Tips When Taking Metformin

While taking Metformin, avoid frequent or large consumption of alcohol. It may increase the lactic acidosis which in turn can cause defects in the functioning of liver and kidney.


FAQs – Things to Know About Metformin

Is Metformin addictive?

No.

Can I have Metformin with alcohol?

No. Having Metformin with alcohol will cause lactic acidosis.

Any particular food item to be avoided?

As Metformin is used as an antidiabetic agent, one should avoid sugar-sweetened beverages, honey, flavoured coffee drinks, dried fruits, etc.

Can I have Metformin when pregnant?

Metformin does not cause any harm to the foetus during pregnancy. It also doesn’t cause any birth complications yet. However, you can take advice from your doctor.

Can I have Metformin when feeding a baby?

Although a small amount of Metformin passes through the breastmilk, it is not reported to cause any adverse effect on the baby. Consult your doctor for better advice.

Can I drive after taking Metformin?

Taking Metformin alone doesn’t affect your driving. If you are taking it with other diabetic medications, it may lower the blood glucose level which results in fainting.

What happens if I overdose on Metformin?

It would cause lactic acidosis with minor symptoms like nausea, vomiting, and diarrhoea. Sometimes it may lead to coma.

What happens if I eat expired Metformin?

It will not be effective in regulating the blood sugar level which can be life-threatening situation.

What happens if I miss a dose of Metformin?

If you miss a dose of Metformin, take it as soon as you remember it. If it is already time for the next dose avoid making up for the missed dose as it would create a double dosage effect.

When Was Metformin Made?

Metformin was made in the year 1972 in Canada.

Also read about other medicine's: Hydroxyzine | Imodium | Insulin

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