What is Metoprolol?

Metoprolol (LOPRESSOR, others) is a 1-selective receptor antagonist that is devoid of intrinsic sympathomimetic activity and membrane-stabilizing activity. Metoprolol is a second generation, 1- selective receptor antagonist.

Manufactured By – Astrazeneca Pharma India Ltd

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Uses of Metoprolol

  • Metoprolol has been used in the treatment of hyperthyroidism.
  • Metoprolol is the most commonly prescribed -blocker for hypertension.
  • Multiple clinical trials show mortality and morbidity benefits with metoprolol in patients with chronic heart failure and post-myocardial infarction.
  • Metoprolol is effective for the prophylaxis of a migraine.

How does Metoprolol work?

These drugs decrease the heart rate, blood pressure, inotropy, and cardiac work, and thereby reduce myocardia oxygen demand.

Metoprolol Price In India

SpecificsMetoprolol Price
25mg Strip of 10 TabletsRs 22.00
Also Read: Plavix Price

How to take Metoprolol?

  • Metoprolol should be taken at the same time every day.
  • Metoprolol should be taken with food or after the meal.
  • Swallow the tablet, do not chew or crush it.

Common Dosage of Metoprolol

  • Appropriate dosing is three to four times daily.
  • The extended-release formulation is sufficiently dosed once daily.
  • For the treatment of hypertension, the usual initial dose is 100 mg/day.
  • Metoprolol generally is used in two divided doses for the treatment of stable angina.
  • For the initial treatment of patients with acute myocardial infarction, an intravenous formulation of metoprolol tartrate is available.
Also Read: Propranolol Dosage | Ranitidine Dosage 

When to avoid Metoprolol

  • Cimetidine and hydralazine may increase the bioavailability of agents such as Metoprolol by affecting hepatic blood flow.
  • Your doctor should be aware of other medicines which you might be taking namely, prazosin, antidepressant (desipramine, fluoxetine, and bupropion), heart or blood pressure medications (clonidine, digoxin, and amlodipine), MAOI (phenelzine, thioridazine) and various others.

Precautions when taking Metoprolol

  • Supersensitivity to isoproterenol also has been observed after abrupt discontinuation of Metoprolol.
  • Metoprolol generally is contraindicated for the treatment of acute myocardial infarction in patients with heart rates of < 45 beats per minute, heart block greater than first-degree (PR interval = 0.24 second), systolic blood pressure <100 mm Hg, or moderate to severe heart failure.

Side Effects of Metoprolol

Some of the reported side effects of Metoprolol are:

  • Dyslipidemia.
  • Diarrhea
  • Memory loss
  • Mild itching or rashes
  • Tiredness
Other medicine's Side Effect: Naproxen Side Effect | Niacin Side Effect

Effects on organs?

  • Cardiovascular- arterial insufficiency, palpitation, first degree heart block, postural disorders.
  • Gastrointestinal- Diarrhea, nausea, dry mouth, gastric pain, constipation, flatulence, heartburn, abdominal pain, vomiting.
  • Nervous system- Dizziness, vertigo, stroke, headache.
  • Respiratory- Shortness of breath, wheezing, dyspnea.
  • Skin- Pruritus, rash.

Storage Requirements for Metoprolol

  • Keep it in a dry, airtight container.
  • Keep Metoprolol away from direct heat or moisture.
  • Keep it out of reach of the children.

Pro Tips When Taking Metoprolol

  • Lowers blood pressure and relieves symptoms of angina in people with heart disease.
  • May be used off-label for other conditions such as migraine prevention and to treat certain arrhythmias.
  • Avoid abrupt discontinuation; stopping Metoprolol suddenly can exacerbate angina and may increase the risk of a heart attack.
  • Do not substitute Metoprolol tartrate with metoprolol succinate and vice versa.


Is Metoprolol addictive?

No, but taking Metoprolol for longer periods may cause withdrawal syndrome.

Can I have Metoprolol with alcohol?

No, drinking alcohol can increase certain side effects of Metoprolol.

Any particular food item to be avoided?

Avoid food containing high potassium, sodium and fat levels.

Can I have Metoprolol when pregnant?

No, Metoprolol is a category C drug and can harm the baby.

Can I have Metoprolol when feeding a baby?

No, Metoprolol passes through and may cause harm, though can be taken only when the benefit outweighs the risk.

Can I drive after taking Metoprolol?

No, Metoprolol may impair your thinking or reactions.

What happens if I overdose on Metoprolol?

Overdosing on Metoprolol may lead to loss of consciousness, drowsy state, minimum to no blood pressure, bluish fingernails, lips, skin.

What happens if I eat expired Metoprolol?

It is advised to not to take expired medicines.

What happens if I miss a dose of Metoprolol?

Take the next dose at the scheduled time. Never take more than the dose for a missed one.

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