Metronidazole: Uses, Dosage, Price, Side Effects, Precautions & More

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Metronidazole: Uses, Dosage, Price, Side Effects, Precautions & More

Metronidazole Composition – Metronidazole 200 MG
Manufactured By – Jagsonpal Pharmaceuticals Ltd.
Prescription – Prescription Required
Form – Tablet
Price – Rs 50
Quantity – 10 tablets in 1 strip

What is Metronidazole?

Metronidazole belongs to a group of medicines called antibiotics. It works by killing bacteria and parasites that cause infections in your body.

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Metronidazole Uses

Metronidazole can be used to:

  • Treat blood infections
  • Treat infectious diseases of the brain, lung, bones, genital tract, pelvic area, stomach, and intestines – Treat infectious diseases of mouth, teeth, and gums.
  • Treat infected leg ulcers and pressure sores
  • Prevent infections after surgery

How does Metronidazole work?

Its exact mechanism of action has not been entirely determined as yet. It has been proposed that Metronidazole works by inhibiting energy production in bacteria and parasites and damages the DNA.


Metronidazole Price in India

Specifics Metronidazole Price
200 mg Strip of 15 Tablets Rs 6.30
Also Read:  Nurokind Price | O2 Price

How to Take Metronidazole?

  • Metronidazole usually comes in the form of tablets and suspensions that has to be taken by mouth with a glass of water as directed by your doctor.
  • Do not crush or chew the tablets.
  • Take these tablets during or just after a meal.
  • Always shake the suspension liquid before consuming to mix the medication evenly.
  • Use a measuring cup to consume the correct dosage of medicine.

Common Dosage For Metronidazole?

  • The dose of Metronidazole will depend on your needs and the illness being treated
  • The length of your treatment will depend on the type of illness you have and how bad it is
  • The usual dose for adults is given below:
  • To treat bacterial infection in adults
  • The initial dose is 800mg.
  • After 8 hours take another dose of 400mg and repeat this dose every 8 hours
Also Read: Nexito Plus Dosage | Nexito Dosage

When to Avoid Metronidazole?

  • Metronidazole doesn’t work in case of viral infections (such as flu, common cold)). Unnecessary use of antibiotic must be avoided because it decreases its efficacy.
  • Avoid taking Metronidazole if you are allergic to metronidazole or nitroimidazoles.
  • Avoid taking Metronidazole if you are suffering from active neurological disorders.
  • Avoid taking Metronidazole if you have a history of blood disease, hypothyroidism or hypoadrenalism.
  • Metronidazole can potentiate the symptoms of known or previously unrecognized candidiasis. Therefore, treatment with an antifungal agent may be required.
  • Laboratory tests – Metronidazole may interfere with certain laboratory tests, such as serum AST, ALT, SGOT, SGPT, LDH, triglycerides, and glucose hexokinase.

Side-effects of Metronidazole?

  • Heart-related: Flattening of the T-wave, flushing, loss of consciousness
  • Central nervous system: Aseptic meningitis, ataxia, confusion, coordination impaired, depression, dizziness, fever, headache, insomnia, irritability, seizure, vertigo hallucinations, convulsions, and a tingling or numbness feeling in the hands, legs, and feet (peripheral neuropathy).
  • Dermatologic: Erythematous rash, itching, Stevens-Johnson syndrome
  • Endocrine & metabolic: Disulfiram-like reaction, dysmenorrhoea
  • Gastrointestinal: Nausea, loss of appetite, abdominal cramping, constipation, diarrhoea, epigastric distress, furry tongue, unusual/metallic taste, vomiting.
  • Genitourinary: darkened urine
Also Read: Normaxin Side Effect | Nucoxia Side Effect | Nurokind Side Effect

What Are The Effects of Metronidazole on Organs?

  • Patients should be warned that Metronidazole may darken urine.
  • Dose must be reduced in patients suffering from liver diseases.

Are There Any Reported Allergic Reactions?

Rarely, an allergic reaction with a skin rash, red, itchy, raised welts on the skin and fever may occur.


Drug Interactions to be careful about

All the possible drug interactions might not be listed here. It is always advised that the patient must inform the physician about of all the drugs/products you use. You must also inform about the herbal products that you are consuming. You must not modify the drug regimen without your doctor’s approval.

Possible drug interactions have been seen with –

  • Disulfiram – Psychotic reactions have been reported in alcoholic patients who are using metronidazole and disulfiram concurrently.
  • Warfarin and other Oral Anticoagulants
  • Lithium
  • Busulfan
  • Drugs that Inhibit CYP450 Enzymes, such as Cimetidine
  • Drugs that Induce CYP450 Enzymes, such as Phenytoin

Shows Effects / Results In

  • You should start to feel recovered during the first few days of treatment with Metronidazole.
  • A complete dose prescribed by your doctor must be taken for the complete cessation of infection from your body (even if the symptoms disappear)

FAQs

Is Metronidazole Addictive?

No, Metronidazole is not addictive.

Can I have Metronidazole with alcohol?

No. You should not consume alcohol/alcoholic beverages or any product containing propylene glycol while being treated with Metronidazole and minimum up to 3 days afterward.

Any particular food item to be avoided?

The following food items must be avoided (known to have anti-platelet activity) –

  • alfalfa,
  • anise,
  • bilberry,
  • grapeseed,
  • green tea,
  • turmeric,
  • fenugreek,
  • garlic,
  • ginger.

Can I have Metronidazole When Pregnant?

  • Always inform your doctor if you are pregnant or plan to become pregnant.
  • Metronidazole is probably safe to be used during pregnancy as there were no adverse results in animal studies.
  • However, due to the lack of human studies, you must always consult your doctor.

Can I have Metronidazole when feeding a baby?

  • Always inform your doctor if you are breastfeeding your child.
  • Caution should be used with caution during lactation. It is advisable to withhold lactation while you are on treatment with Metronidazole.
  • A lactating mother can alternatively opt to pump and discard human milk as long as she is on treatment with Metronidazole, and for 24-48 hours after the course ends and feed her child stored human milk or formula.

Can I drive after taking Metronidazole?

You should not drive if you feel dizzy, drowsy or less alert than normal after taking Metronidazole.

What happens if I overdose on Metronidazole?

  • An overdose of Metronidazole might cause nausea, vomiting, and loss of coordination.
  • If you have taken an overdose, it is advisable to contact your consulting physician immediately.

What happens if I eat expired Metronidazole?

The antibiotic may not work as well. Please inform your physician regarding the same.

What happens if I miss a dose of Metronidazole?

  • If you miss a dose of Metronidazole, take it as soon as possible.
  • However, if it is time for your next dose, do not double the dose, just carry on with your regular schedule.

Storage Requirements for Metronidazole

Store below 25C in original packing and protect from direct light and moisture.


Pro Tips When Taking Metronidazole

  • Metronidazole may cause decreases in white blood cells (needed to help fight infection) as well as increases in liver enzymes (sign of liver damage). Blood tests should be done regularly to check if there are any changes in these values.
  • If you are suffering from diarrhoea, you must consume appropriate amounts of fluids or rehydration drinks in order to avoid dehydration.
Other medicine to read: Ofloxacin

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