Neosporin: Uses, Dosage, Side Effects, Price, Composition & 20 FAQs

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Neosporin: Uses, Dosage, Side Effects, Price, Composition & 20 FAQs

What is Neosporin?

Neosporin belongs to a group of drugs called as “antibiotic ointment”. Neosporin contains Bacitracin, Neomycin and Polymyxin B as chief ingredients. These anti-infective components in the combination are included to provide action against specific microorganisms susceptible to them. The use of Neosporin skin ointment does not exclude concomitant systemic therapy with antibiotics where appropriate.

Composition: Bacitracin 400 units, Neomycin 3.5 mg, Polymyxin B 5,000 units
Manufactured by – GlaxoSmithKline Inc
Prescription– Not required as it is available as over the counter (OTC) drug
Form – Ointment
Price – Rs. 87.75
Type of Drug –
Antibiotic Ointment


Uses of Neosporin

Neosporin antibiotic skin ointments is used in cases when bacterial skin infection is present or likely to occur. These include:

  • To prevent infection in graft donor sites, lacerations, cuts, scratches and abrasions.
  • Treatment of infected ulcers.
Read more: Normaton Uses

How Does Neosporin Work?

  • Neosporin contains 3 major ingredients – Neomycin, Polymyxin and Bacitracin.
  • These anti-infective components in the combination are included as they stop the bacterial growth and provide action against specific microorganisms susceptible to them.

How to Take Neosporin?

  • Neosporin is available in the form of skin ointment.
  • A small amount of Neosporin should be applied to the affected area after necessary removal of debris, such as pus, crusts, etc. from the affected area.
  • Neosporin must be applied in a thin layer and evenly to the skin as prescribed by your physician.
  • Clean and dry the area on which Neosporin has to be used.
  • Hands should be properly washed before and after applying Neosporin.
  • The area treated with Neosporin should not be washed immediately after cream application.
  • The area treated may be covered with gauze dressing if desired. .
  • Eye – A thin film of the ointment may be applied directly to the affected area; alternatively, a ribbon of ointment may be placed inside the lower eyelid.

Common Dosage for Neosporin

  • The drug dosage is decided by the physician based upon:
  • Health status/medical condition of the patient
  • Severity of symptoms
  • Reaction to the first dose
  • History of allergy/drug reactions
  • Dosage in adults: apply a small amount of this productNeosporin skin ointment (an amount equal to the surface area of the tip of a finger) on the affected area one to three times daily.

Q. What happens if I overdose on Neosporin?

Neosporin should not be applied in more than prescribed dose. If you have applied an over-dose, it is advisable to wash it with cold water and contact your consulting physician.

Q. What happens if I miss a dose of Neosporin?

The potency of the medicine may decrease because for effective working of the drug, a certain amount of drug must be present in your body at all times. Always apply the missed dose as soon as you remember. But, if it’s already time for the next dose – do not double the dose.

Q. What happens if I eat expired Neosporin?

The medicine may not work as well as the potency of the medicine gets affected. Please inform your physician regarding the same. To be on the safer side, always check and never use an expired medicine.

Q. What is the onset time of Neosporin? 

You should start to feel recovered within 3-4 days following treatment with Neosporin.

Q. Till When Does The Effect of Neosporin Stay?

The duration of time for which the medicine remains effective is not clinically established.

Read more: Mim Orange Dosage

When to Avoid Neosporin?

Do not Consume Neosporin in the following scenarios:

  • Allergy – if the patient is allergic to any of the components present in Neosporin.
  • Due to the known potential of neomycin sulphate for ear and kidney toxicity, the use of Neosporin in large quantities for longer periods of time is not recommended in conditions where significant systemic absorption (absorption within the blood stream) can occur.
  • Neonates and infants (less than 2 years) – due to a possibility of increased absorption
  • Presence of pre-existing nerve deafness.
  • Neosporin should not be used to treat ear infections in the presence of a perforated tympanic membrane (ear drum) because of the risk of ear toxicity.
  • Neosporin should not be used during surgical procedures in cases where the ointment could gain access to eye fluids.

Precautions While Taking Neosporin

  • Neosporin antibiotic ointment can be used for skin and ophthalmic use but the same tube should not be used simultaneously for skin and eye infections i.e. two separate tubes should be used.
  • The use of Neosporin skin ointment does not exclude concomitant systemic therapy with antibiotics where appropriate.
  • Avoid prolonged use as it may result in the overgrowth of nonsusceptible organisms like fungal growth.
  • Ointment should not be used in the eyes.

Side-Effects of Neosporin

Majority of the patients do not show any side effects. Few patients might show side effects which include:

  • Application site reaction including pain, redness, swelling, itching and exacerbation of underlying skin conditions.
  • Following significant systemic absorption: neomycin can cause irreversible ear toxicity.
  • Neomycin sulfate, polymyxin B sulfate, and bacitracin zinc have kidney damaging potential.
  • Polymyxin B sulfate has nerve damaging potential.

Are There Any Reported Allergic Reactions to Neosporin?

Possible allergic reactions reported for Neosporin are:

  • Rash (common)
  • Itching (common)
  • Shortness of breath (less common)
  • Swelling of face, lips, tongue, or throat (rare)
  • Loss of consciousness (rare)

What Are The Effects of Neosporin on Organs?

Patients with pre-existing kidney disease should use it with caution and under medical supervision.

Drug Interactions With Neosporin to be Careful About

Drug interaction refers to effect of drugs on each other and on human body after ingestion. Large numbers of medicines have shown to interact with each other. Interactions are not just limited to drugs, but certain food items and some laboratory tests which should not be taken right after consuming Neosporin. We explore these in details below.

1. Food Interactions with Neosporin 

No interactions observed with any food products.

2. Medicines Interactions with Neosporin

It is always advised that the patient must inform the physician about all the drugs/over the counter products/vitamin supplements used. It may interact with large number of medicines. Few important ones include:

  • You must also inform about all other medicines including antibiotics that you are consuming. You must not modify the drug regimen without your doctor’s approval.
  • If you need to use other drugs on same area of skin it is advisable to leave a gap of few minutes between each application so as to avoid mixing of two drugs.
  • If you need to use a moisturiser, it is advisable to apply it 30 minutes before applying Neosporin so as to soften the skin surface and allow enhanced absorption of Bactifix.
  • Please note that application of moisturiser just before/after application of Neosporin can dilute the drug and decrease its effectiveness.

3. Effects of Neosporin on Lab Tests

No effect on any lab tests noted while taking Neosporin.

4. Neosporin’s interactions with Pre-existing Conditions/Diseases

Patients suffering from pre-existing kidney diseases and perforated ear drum must consult their physician before consuming Neosporin.

Q. Can I have Neosporin with alcohol?

Neosporin is usually not known to interact with alcohol. However, alcohol consumption must be avoided due to lack of clinical data.

Q. Any particular food item to be avoided?

No alteration in its action seen with any food product.

Q. Can I have Neosporin when pregnant?

Always consult your doctor first. Always inform your doctor if you are pregnant or plan to become pregnant.

Q. Can I have Neosporin when feeding a baby?

There is no evidence as whether ingredients of Neosporin are excreted in human breast milk or not thus it should be used with caution in lactating mothers.

Q. Can I drive after taking Neosporin?

Neosporin is not generally known to affect your ability to drive.

Read more: Neuragen Side Effects | Oxynerve Plus Side Effects

Neosporin Composition, Variant and Price – Buyer’s Guide

Neosporin Variants Neosporin Composition Neosporin Price (Rs.)
Neosporin Dusting Powder Bacitracin 400 units, Neomycin 3.5 mg, Polymyxin B 5,000 units Rs. 64.7
Neosporin Pain relief cream Neomycin, Polymyxin B, Pramoxine Rs. 40.95
Neosporin Pain Itch Scar Bacitracin, Neomycin, Polymyxin B, Pramoxine Rs. 87.75
Buy & save form: Myra Medicines | 1mg | Practo

Substitutes of Neosporin

The following are alternative drugs for Neosporin:

  • Nebazine Ointment:
    • Manufactured by –AAA Pharma Trade Pvt Ltd
    • Price – Rs. 108.5
  • Nebaspor Ointment:
    • Manufactured by – Intas Pharmaceuticals Ltd
    • Price –Rs. 34.5
  • Nexporin Ointment:
    • Manufactured by – Scott Edil Pharmacia Ltd
    • Price – Rs. 50

Storage Requirements for Neosporin 

  • Storage at room temperature away from direct light and heat unless mentioned in the package insert.
  • Keep medicines away from children and pets.

FAQs – 10 Important Questions Answered about Neosporin

Q. What is Neosporin?

Ans. Neosporin belongs to a group of drugs called as “antibiotic ointment”. Neosporin contains Bacitracin, Neomycin and Polymyxin B as chief ingredients. These anti-infective components in the combination are included to provide action against specific microorganisms susceptible to them. The use of Neosporin skin ointment does not exclude concomitant systemic therapy with antibiotics where appropriate.

Q. What are the uses of Neosporin?

Ans. The use of Neosporin skin ointment does not exclude concomitant systemic therapy with antibiotics where appropriate.

Q. What are the side effects of Neosporin?

Ans. The most common side effects of Neosporin are Application site reaction including pain, redness, swelling, itching and exacerbation of underlying skin conditions, Following significant systemic absorption: neomycin can cause irreversible ear toxicity, Neomycin sulfate, polymyxin B sulfate, and bacitracin zinc have kidney damaging potential, Polymyxin B sulfate has nerve damaging potential.

Q. How effective is Neosporin?

Ans. Neosporin is effective ue to its antibiotic properties. However as an antibiotic ointment, there are other medicines which perform better.

Q. How long does it take for Neosporin to show results?

Ans. You should start to feel recovered within 3-4 days following treatment with Neosporin.

Q. Should Neosporin be taken on an empty stomach?

Ans. Neosporin is a skin ointment. You can apply the medicine with or without food.

Q. Does Neosporin make you drowsy?

Ans. Neosporin does not make you drowsy.

Q. What should be the time gap between the intake of 2 Neosporin?

Ans. Neosporin is usually applied after a gap of 4-6 hours after the first dose.

Q. Should I complete the whole cycle of the medicine even if cured?

Ans. A complete course must be taken for complete cessation of symptoms from your body.

Q. Does Neosporin effect my menstrual cycle?

Ans. No, Neosporin does not affect your menstrual cycle.

Q. Is Neosporin safe for children?

Ans. Neosporin is safe for consumption in children above 12 years of age. Children below 2 years should use it with caution.

Q. Are there any symptoms that I should consider before taking Neosporin?

Ans. Patients with history of allergic reaction to any of the ingredients of Neosporin and history of kidney disease and ear drum perforations should use it with caution.

Q. Is Neosporin legal in India?

Ans. Yes, it is legal.


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Disclaimer – The information provided above is to the best of our research and knowledge. However, you are recommended to consult a physician before consuming the drug.

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