Orlistat: Uses, Dosage, Price, Side Effects, Precautions & More

Orlistat: Uses, Dosage, Price, Side Effects, Precautions & More

Orlistat Composition – Orlistat 120 MG
Manufactured By – Windlas
Prescription – Prescription Required
Form – Tablet
Price – Rs 375
Quantity – 10 tablets in 1 strip

What is Orlistat?

Orlistat is an anti-obesity medicine that helps in reducing the weight of obese patients. Orlistat blocks some of the fat from the food, keeping it from being absorbed by the body. Orlistat is for use only in adults. Orlistat is only part of a complete program of treatment that also includes diet, exercise, and weight control.

Manufactured By – GlaxoSmithKline

Other variants and composition – 

Variant Composition
Orlistat 120Mg Tablet Orlistat 120 MG
Orlistat 60Mg Capsule Orlistat 60 MG
Buy & Get Minimum 20% Discount: Saveonmedicals | Practo

Uses of Orlistat

Orlistat is used for

  • Weight loss.
  • To treat obesity.

How does Orlistat work?

  • Dietary fats need to be broken down into smaller pieces before the body can absorb them. Orlistat works by blocking the enzyme that breaks down fats.
  • It inhibits gastric and pancreatic lipase breakdown and absorption of dietary fats.
  • This undigested fat then passes out of the body.
  • Orlistat does not block the absorption of calories from sugar and other non-fat foods, so you still need to restrict your total intake of calories.

How to take Orlistat?

  • You may take Orlistat either with your meal or up to 1 hour after eating.
  • Orlistat is usually taken 3 times per day with each main meal that contains some fat (no more than 30% of the calories for that meal).

Orlistat Price In India

Specifics Orlistat Price
120mg Strip of 10 Tablets Rs 375
Also Read: Propranolol Price | Ranitidine Price | Ritalin Price

Common Dosage of Orlistat

  • The usual dosage for obesity is 120 mg orally three times a day with each main meal containing fat.
  • The dose may be taken during the meal or within 1 hour of completing the meal.

When to avoid Orlistat?

  • Using warfarin and lamotrigine together with Orlistat can cause you to bleed more easily. You may need a dose adjustment.
  • Combination of levothyroxine and Orlistat at the same time may reduce the blood levels of levothyroxine. You should take these medications at least four hours apart.
  • Treatment with Orlistat, with metformin or any other diabetic medications, may require a change in dosage.
  • Do not take Orlistat if you use cyclosporine; it can prevent organ transplantation.

Precautions while taking Orlistat

  • Avoid taking Orlistat if you are allergic to it or to any of its components.
  • Do not take Orlistat if you are pregnant or have digestive or gallbladder problems.
  • High-fat meals taken in combination with Orlistat can increase your risk of unpleasant side effects on your stomach or intestines.
  • Do not take Orlistat if you use cyclosporine; it can prevent organ transplantation.

Side Effects of Orlistat

Some of the reported side effects of Orlistat are:

  • Abdominal pain
  • Flatulence
  • bowel urgency/frequent bowel movements
  • Decreased absorption of fat-soluble vitamins.
  • Headache
  • Vomiting
  • Unusual tiredness and weakness
  • Tooth problems
  • Trouble sleeping
  • Itching
  • Yellow colored eyes or skin
  • Menstrual changes
  • Rectal pain
Also Read: Metoprolol Side Effect | Naproxen Side Effect | Niacin Side Effect

Effect on organs?

  • Gastrointestinal reactions- flatus with discharge, fecal urgency, fatty/oily stool, increased defecation, abdominal pain, nausea, infectious diarrhea, rectal pain, vomiting.
  • Nervous reactions- headache and dizziness.
  • Psychiatric reactions- Sleep disorder, anxiety, and depression.
  • Respiratory reactions- Influenza, upper respiratory infection, lower respiratory infection.
  • Muscle and bone reactions- Back pain, arthritis, myalgia, joint disorder, tendonitis.
  • Genitourinary reactions- Menstrual irregularity, vaginitis, urinary tract infection.
  • Cardiovascular reactions- Pedal edema.

Storage Requirements for Orlistat

  • Keep it in a dry, airtight container.
  • Keep it away from direct heat or moisture.
  • Keep Orlistat out of reach of the children.

Pro Tips When Taking Orlistat

  • If you skip a meal or you eat a meal that does not contain any fat, skip your dose for that meal.
  • Follow your diet, medication, and exercise routines very closely.
  • Multivitamins are recommended while taking Orlistat.


Is Orlistat addictive?

No, Orlistat is not addictive.

Can I have Orlistat with alcohol?

Yes (be cautious about the number of calories you might be taking).

Any particular food item to be avoided?

Avoid food containing more than 30% fat.

Can I have Orlistat when pregnant?

No, you should not have Orlistat when pregnant.

Can I have Orlistat while feeding a baby?

No,  you should not have Orlistat while feeding a baby.

Can I drive after taking Orlistat?

Yes, you can drive after taking Orlistat.

What happens if I overdose on Orlistat?

Overdosing on Orlistat may cause symptoms like nausea, vomiting, diarrhea, gas, abdominal distress, oily feces and incontinence of feces.

What happens if I eat expired Orlistat?

Expired medicines may have lost potency and will not be as effective as earlier. Sometimes it can be harmful to the body.

What happens if I miss a dose of Orlistat?

Take the missed dose as soon as you remember it. Skip the missed dose, if it’s time for the next dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

Also read about other medicine's: Oseltamivir | Plavix


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