Plavix: Uses, Dosage, Price, Side Effects, Precautions & More

Plavix Composition – Clopidogrel (75mg)
Manufactured By – Sanofi India Ltd
Prescription – Prescription Required
Form – Tablet
Price – Rs 102.23
Quantity – 14 tablets in 1 strip

What is Plavix?

Plavix block the actions of ADP on platelets. These drugs are an alternative to aspirin for patients. Plavix is currently much more widely used than ticlopidine. Plavix is a prodrug with a slow onset of action. Plavix is used to prevent thrombosis after coronary angioplasty and in the secondary prevention of myocardial infarction and stroke.

Manufactured By – Sanofi India Ltd

Other variants and composition – 

Plavix 75Mg Tablet – Clopidogrel 75 MG

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Uses of Plavix

Plavix is used to treat:

  • Acute coronary syndrome.
  • Coronary stenting.
  • Decreased incidence or recurrence of thrombotic stroke.
  • Plavix should be prescribed in addition to aspirin for patients undergoing PCI with a stent.
  • Plavix may also be prescribed as an alternative when aspirin is contraindicated, or to those intolerant to aspirin, in patients with recurrent cardiac events.
  • Plavix should be continued for at least a month after fibrinolytic therapy, or for up to 9-12 months after stent implantation, depending on the type of stent used.
Also Read: Metoprolol Uses | Naproxen Uses | Niacin Uses

How does Plavix work?

Plavix works by preventing the formation of clots in blood vessels and helps in free blood flow.


How to take Plavix?

  • It is advised to take Plavix at the same time every day.
  • It is taken with or without food, once a day.

Plavix Price In India

SpecificsPlavix Price
75mg Strip of 14 TabletsRs 102.23

Common Dosage for Plavix

  • The usual dose is 75 mg/day with or without an initial loading dose of 300 or 600 mg.
  • Plavix is somewhat better than aspirin in the secondary prevention of stroke, and the combination of Plavix plus aspirin is superior to aspirin alone for the prevention of recurrent ischemia in patients with unstable angina.

When to avoid Plavix?

  • Do not combine aspirin and Plavix for a stroke. Combination of antiplatelet agents is used on coronary disease but not a cerebral disease.
  • Do not use non-prescription medications that contain PPIs (such as omeprazole, esomeprazole) or cimetidine for relief of upset stomach or heartburn. These medications can prevent Plavix from working well.
  • Nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen, naproxen, or aspirin which can increase the risk of bleeding or anti-platelet effect when used with Plavix.
  • Acid reducers (PPIs such as omeprazole, esomeprazole), fluvoxamine, fluoxetine, cimetidine, fluconazole, ketoconazole, voriconazole, etravirine, felbamate, and ticlopidine, among others may cause Plavix to not work effectively.
  • Tipranavir, antidepressants (amitriptyline, clomipramine, SSRIs including paroxetine or citalopram, SNRIs including duloxetine or venlafaxine) may interact with Plavix.

Precautions while taking Plavix

  • Avoid Plavix if you are allergic to it or to any of the components present in it.
  • It is not recommended in patients with bleeding disorders.
  • Avoid Plavix in patients likely to require emergency coronary bypass surgery.
  • Sudden stoppage of Plavix may increase the risk of heart diseases.

Side Effects of Plavix

The rare adverse effects of Plavix are:

  • White patches in the mouth or on the tongue
  • Redness of skin
  • Difficulty in breathing
  • Blood in urine and stools
  • Headache
  • Severe neutropenia
  • Thrombocytopenia.

Effects on organs?

  • Gastrointestinal reactions- Abdominal pain, gastrointestinal hemorrhage, dyspepsia, diarrhea, nausea, gastritis.
  • Cardiovascular reactions- Chest pain, hypertension, angina pectoris, coronary artery disorder, peripheral ischemia.
  • Nervous system reactions- Dizziness, headache.
  • Respiratory reactions- Upper respiratory tract infection, dyspnea, rhinitis, coughing, bronchitis, epistaxis.
  • Psychiatric reactions- Depression.
  • Skin reactions- Rash, purpura, pruritus, bruising.

Storage Requirements for Plavix

  • Keep Plavix in a dry, air tight container.
  • Keep it away from direct heat or moisture.
  • Keep it out of reach of the children.

Pro Tips When Taking Plavix

  • Plavix is available as a generic under the name Plavix.
  • The dosage of Plavix does not need adjusting in people with liver disease.
  • It can be taken in combination with other anti-platelets for a better action.
  • If possible, discontinue Plavix 5 days before coronary bypass surgery.
  • If there occurs a bruise or bleed, more easily, it will take longer to stop bleeding while you are taking Plavix. This shows the medicine is working but if the bleeding gets severe, call your doctor.

FAQs

Is Plavix addictive?

No.

Can I have Plavix with alcohol?

No.

Any particular food item to be avoided?

Limit your fat, cholesterol and sodium intake.

Can I have Plavix when pregnant?

Yes, only if the benefit outweighs the risks.

Can I have Plavix while feeding a baby?

Yes, only if the benefit outweighs the risks.

Can I drive after taking Plavix?

Yes, only if you are aware of how Plavix affects your thinking ability and alertness.

What happens if I overdose on Plavix?

Overdosing on Plavix may result in bleeding complications.

What happens if I eat expired Plavix?

Expired medicines may have lost potency and will not be as effective as earlier. Sometimes it can be harmful to the body.

What happens if I miss a dose of Plavix?

Take the missed dose as soon as you remember it. Skip the missed dose, if it’s time for the next dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

Also read about other medicine's: Propranolol | Ranitidine
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