Remicade (Infliximab): Uses, Dosage, Price, Side Effects, Precautions & More

Remicade (Infliximab): Uses, Dosage, Price, Side Effects, Precautions & More

What is Remicade?

Remicade belongs to a group of drugs which are used for the treatment of autoimmune diseases like rheumatoid arthritis, psoriasis etc. The active ingredient of Remicade is Infliximab which is a blocker of Tumour necrosis factor (chemical mediator which causes inflammation). Remicade is available as a sterile white powder for intravenous infusion following reconstitution with sterile water.

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Uses of Remicade

Remicade (Infliximab) is most commonly used in the prevention and treatment of the following conditions:

  • Rheumatoid arthritis
  • Psoriasis
  • Ulcerative colitis
  • Crohn’s disease
  • Ankylosing spondylitis
  • Psoriatic arthritis

Remicade may also be used for a purpose not mentioned above.


How Does Remicade (Infliximab) Work?

Remicade acts by inhibiting a protein in immune system called as tumour necrosis factor which causes inflammation (pain and swelling) in involved organs.


Remicade Price In India

Specifics Remicade Price
100 mg Vial of 1 Powder for Injection Rs 41039.00
Also read about other medicine's Price: Voltaren Price

How to Take Remicade?

  • The dose and duration of treatment with Remicade depend upon the severity of the condition and initial response to treatment.
  • Remicade (Infliximab) is usually administered via intravenous injection for a time period of not less than 2 hours.
  • Following administration of Remicade, adverse effects like a headache, flu-like symptoms, decreased blood pressure, GIT symptoms, chills etc have been observed.
  • Inspect the solution for any discolouration or particulate matter before administration. Do not reuse if any unused solution is left behind.

Common Dosage & When to Take Remicade?

  • The usually recommended dose of Remicade is 5mg/kg at 0, 2 and 6 weeks then every 8 weeks.
  • For patients who do not respond, the dose can be raised up to 10mg/kg.
  • Using Remicaid may increase your risk of developing fatal infections like Tuberculosis, invasive fungal infections and malignancies like lymphoma.
  • Discontinue treatment with Remicade if a patient develops any serious infection and consult your doctor immediately.
Also Read: Ultram Dosage | Ventolin Dosage

When to Avoid Remicade (Infliximab)

Remicade should not be used or should be used with caution when:

  • Allergic to any of its components
  • People with liver or kidney problem
  • Pregnant and breastfeeding females
  • Patients with suppressed immune system
  • Patients with serious infections
  • Patients with Severe heart failure
  • Cancer patients
  • Epileptic patients
  • Patients due to receive vaccinations

Side effects of Remicade?

Remicade (Infliximab) may produce multiple side effects, although they may not be common in all the patients. Commonly observed side effects:

  • Infections (upper respiratory, sinusitis etc)
  • Headache
  • Abdominal pain
  • Flushing
  • Difficulty in breathing
  • Nausea
  • Diarrhoea
  • Rash
  • Fatigue
  • Joint pains
  • Changes in blood pressure
  • Liver problems
  • Decreased blood cell (WBC, RBC, Platelet) count
Also Read: Singulair Side Effect | Suboxone Side Effect | Synthyroid Side Effect

Effects on organs?

Patients with liver and kidney disease should administer Remicade (Infliximab) with caution and under the observation of a doctor.


Reported Allergic Reactions?

Tell your doctor if you are allergic to any of its ingredients. Allergy with Remicade may exhibit following symptoms:

  • Rash
  • Chest tightness
  • Itching
  • Shortness of breath
  • Swelling of face, lips, tongue, or throat.

Drug Interactions to Be Careful About

Drug interactions refer to the effect of drugs on each other and on human body following ingestion. Large numbers of medicine have shown interaction with each other. It is advised that the patient must always inform the physician about all the medicines/over the counter products/vitamin supplements used. Consult your doctor before administering any other drugs concomitantly with Remicade (Infliximab). All the possible drug interactions might not be listed here. Few important ones include:

  • Alcohol
  • Methotrexate
  • Corticosteroids
  • Warfarin
  • Cyclosporine
  • Live vaccines
  • Ciprofloxacin
  • Metronidazole

Shows Effects / Results In

Few patients with Remicade therapy feel better quite quickly while others may take longer following IV administration.


FAQs

Is Remicade (Infliximab) Addictive?

No such tendency has been reported.

Can I have Remicade with alcohol?

Interaction of Remicade with alcohol may increase the risk of liver damage in patients. Liver cirrhosis has also been reported in heavy drinkers taking Remicade.

Any particular food item to be avoided?

No alteration in its action seen with any food product.

Can I have Remicade (Infliximab) when Pregnant?

  • It is not known whether Remicade causes any adverse effects on foetus when administered in pregnant women as animal studies have not been conducted.
  • Remicade should, therefore, be administered only if the needs outweigh the risks involved.

Can I have Remicade when feeding a baby?

Remicade (Infliximab) should only be used in breastfeeding women if there is significant need as the drug may pass into breast milk and lead to adverse effects in foetus.

Can I drive after taking Remicade?

Remicade (Infliximab) does not usually affect your ability to drive.

What happens if I overdose on Remicade?

  • It should not be administered in more than prescribed dose or frequency.
  • Taking more medication or with increased frequency can cause serious toxicity (abnormal liver function test, liver cirrhosis)

What happens if I eat expired Remicade (Infliximab)?

  • The medicine may not work as well as the potency of the medicines decreases and also it may lead to some adverse effects.
  • To be on the safer side, always check and never use an expired drug.

What happens if I miss a dose of Remicade?

  • The medicine may not work well if you miss a dose because, for effective working of the drug, a certain amount of drug must be present in your body at all times.
  • Always consume the missed dose as soon as you remember. But, if it is already time for the next dose – do not double the dose.

Storage of Remicade (Infliximab)

  • Storage at room temperature away from direct heat and light.
  • Keep medicines away from children and pets.

Pro Tips When Taking Remicade

As Remicade (Infliximab) is an immunosuppressant and decreases body’s immunity, there are increased chances of developing severe infections like Tuberculosis, invasive fungal infections and malignancies like lymphoma.


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