Rifagut 400 MG Tablet: Uses, Dosage, Side Effects, Price, Composition & 20 FAQs

What is Rifagut?

Used mainly to treat conditions like Traveller’s diarrhea, irritable bowel syndrome, and intestinal infection. Green or black colored stools and confusion at repetitive high doses are the major side effect. It should be totally avoided in case of liver diseases, drug resistance and allergic reactions.

Rifagut Composition: Rifaximin 200mg
Manufactured by:Sun Pharmaceutical Industries Ltd.
Prescription: Required as it comes under schedule ‘H’
Form: Tablets.
Price: Rs 150.00 for 10 tablets.
Expiry/Shelf Life: 24 months from the date of manufacturing
Type of Drug:  

Also Read in Hindi About Rifagut

Uses of Rifagut

Rifagut serves a great purpose in the treatment of the following conditions:

  • Infection: Used in cases of bacterial infection of intestine.
  • IBS: Used in cases of IBS (Irritable bowel syndrome).
  • Hepatic Encephalopathy: Used to treat cases of decline in brain function due to severe liver disease (hepatic encephalopathy).
  • Diarrhoea: Used to treat cases of Traveller’s diarrhoea (caused by E.coli).
  • Liver Failure: Used in cases of patients with liver

How does Rifagut work?

  • Rifagut contains Rifaximin as its active ingredient.
  • Rifaximin is an antibiotic, which works by inhibiting the RNA synthesis of the bacterial cells and thus causing the death of bacterial cells.
  • Rifagut helps by preventing further bacterial growth by killing the bacterial cells.

How to take Rifagut?

  • Rifagut is usually available in tablet form for use.
  • Rifagut tablet is usually taken by mouth with a glass of water, with or without food (preferably with or after food) or as advised by the doctor.
  • Rifagut tablets should be swallowed as a whole instead of crushing or chewing it.
  • Complete dose as prescribed by the doctor should be taken.
  • It is advisable to go through the drug leaflet available in the packet insert.
  • Equally spaced time interval should be there between two doses.

Common Dosage for Rifagut

  • Rifagut dosage can be decided by the doctor for every individual as per: Age, Weight, Mental status, Allergic history and Health status of the patient.
  • Common Adult Dose for Traveler’s diarrhoea is a single 200 mg tablet thrice a day for three days.
  • Common Adult Dose for Hepatic encephalopathy is a single 550 mg tablet twice a day.
  • For patients less than 18 years of age, it is not advisable as its safety is not yet established for this particular age group.
  • It is safer to consult the pediatrician before administering the pediatric dose.
  • Prolonged use or dose alteration should be avoided unless stated otherwise by the doctor.

Q. What happens if I overdose on Rifagut?

An overdose of Rifagut can cause serious side effects, so the dose of the drug should be taken carefully as prescribed by the doctor and Consult the Medical Staff or the doctor immediately in case of Rifagut overdose.

Q. What happens if I miss a dose of Rifagut?

The dose prescribed by the doctor should never be missed and if missed, it should be consumed always as soon as you remember it. But, avoid taking a double dose if it’s already time for the second dose after that as it may lead to an overdose of the drug.

Q. What happens if I eat expired Rifagut?

The expired dose of Rifagut is very unlikely to cause any undesired effect however, the physician should be consulted in case of any sickness or symptoms after consuming an expired medicine. An expired drug is not potent enough to treat the condition and one should avoid consuming the expired drug.

Q. Onset time of Rifagut and till when does the effect of Rifagut stays?

  • Rifagut can take a few days to show its effect against the symptoms after starting with the drug therapy.
  • The time taken by the drug to show its effect may vary with every individual.

When to Avoid Rifagut?

Do not Consume Rifagut if:

  • Liver disorders: In patients having liver problems, Rifagut should be avoided unless stated by the doctor (Rifagut is advised in patients of liver failure).
  • Allergy: In known cases of allergy to Rifagut or any of its ingredients or history of hypersensitivity in the past.
  • Drug Resistance: Should be avoided in cases of drug resistance with rifagut.
  • Diarrhoea: Should be avoided in diarrhoea not caused by E.coli and Clostridium difficile associated diarrhoea.

Precautions While Taking Rifagut

  • Liver diseases: The drug should not be administered in patients with the liver disease without doctor’s consultation.
  • Timing: The drug should be consumed at fixed timing to avoid any overdose of drug.
  • Dose alteration: Consuming a high dose without medical consultation should be avoided.

Warnings When Taking Rifagut

  • Complete the prescribed course: It is advisable to complete the entire prescribed dose of Rifagut, even after the symptoms start to disappear.
  • Diarrhoea not caused by E.coli: Should not be used in diarrhoea complicated by fever or blood in stool or diarrhoea caused due to other microbes.

Side-Effects of Rifagut

The side effects associated with Rifagut are:

  • Abdominal Pain (common)
  • Bloating (Common)
  • Fatigue (less common)
  • Confusion (less common)
  • Sleep disorder (less common)
  • Green or black colored stools (rare)
  • Dizziness (less common)
  • Stomach upset (Common)
  • Headache (Less Common)

Are There Any Reported Allergic Reactions to Rifagut?

  • In case of allergic reaction with signs like itching, redness, and rashes, immediate medical help should be taken.
  • Patients with a known history of allergy to Rifagut or its ingredient are more prone to allergic reactions.
  • In the case of an allergic reaction, Patient should consult the doctor immediately and should stop the drug as per the doctor’s advice.

What are the effects of Rifagut on organs?

  • Rifagut can affect hepatic functions therefore, extra caution or dose modification is required in cases of hepatic or diseases.

Drug Interactions to be Careful About

It is always advisable to be careful of a certain drug to drug or drug to food interactions when consuming Rifagut. Always be aware of the food items, other drugs or lab tests while consuming Rifagut. We explore these n details below.

1. Food Interactions with Rifagut

No particular food item to be avoided.

2. Medicines Interactions with Rifagut

All the potential drug interactions might not be listed here. It is always advisable that the patient must inform the physician about of all the drugs/products you use. You must notify the doctor about the herbal products that you are currently consuming. You should never alter the drug regimen without your doctor’s approval.

The common drug interactions have been noticed with the following drugs:

  • Warfarin (mild)
  • Midazolam (moderate)
  • Ketaconazole (mild)
  • Pantoprazole (moderate)
  • propanolol (mild)
  • Oral contraceptives (moderate)

3. Effects of Rifagut on Lab Tests

Rifagut does not affect any lab results as such.

4. Rifagut’s interactions with Pre-existing Conditions/Diseases

Any Liver diseases, allergic reactions.

Q. Can I have Rifagut with alcohol?

No, Rifagut’s interaction with alcohol is not known. Therefore, it is advised to avoid consuming alcohol while taking Rifagut.

Q. Any particular food item to be avoided?

No particular food item is to be avoided.

Q. Can I have Rifagut when pregnant?

No, avoid taking Rifagut when pregnant as animal studies have shown adverse effects on foetus. Therefore, the doctor should always be informed in case of pregnancy or plans of conceiving for case specific recommendations.

Q. Can I have Rifagut when feeding a baby?

No, evidence of Rifagut secretion in human milk is not known. Therefore, the doctor should always be informed if you are breastfeeding your child as a precautionary measure.

Q. Can I drive after taking Rifagut?

Yes, as Rifagut does not affect the ability to drive. However, one should avoid driving or operating heavy machinery if any dizziness or drowsiness occurs.

Also Read: Primolut N Side Effect | Rablet D Side Effect | Rantac Side Effect

Buyer’s Guide – Rifagut Composition, Variant and Price

Rifagut VariantsRifagut CompositionRifagut Price
Rifagut 400mg TabletRifaximin 400mgRs. 279.00 for 10 tablets
Rifagut 550mg TabletRifaximin 550mgRs. 360.00 for 10 tablets
Buy & Get Discount: Practo Coupons

Substitutes of Rifagut

The following are alternative drugs for Rifagut:

  • Gutwin 200mg tablet:
    • Manufactured by – Win Medicare
    • Price – Rs. 97.88
  • Rcifax 200mg tablet:
    • Manufactured by – Lupin Ltd.
    • Price – Rs. 165
  • Rifastop 200mg tablet:
    • Manufactured by – Mankind Pharma Ltd.
    • Price – Rs. 148.50
  • Rifabet 200mg tablet:
    • Manufactured by – FDC Ltd.
    • Price – Rs. 137

Storage requirements for Rifagut Tablets

  • Store the drug protected from light, moisture and direct heat at a temperature below 30OC
  • Keep at a place where it is out of reach of children.
Also Read: Razo D Price | Regestrone Price | Remylin D Price

FAQs – 10 Questions Answered about Rifagut

Q. What is Rifagut?

Ans. Rifagut is a form of antibiotic drug which contains Rifaximin as its main active ingredient. Rifagut is used mainly to prevent and treat conditions like Traveller’s diarrhoea and Irritable bowel syndrome.

Q. How effective it is/ How long does it take for Rifagut to show results?

Ans. Rifagut shows its effect within a few days of starting the drug therapy.

Q. Should Rifagut be taken on an empty stomach?

Ans.  Rifagut should be taken after meals to prevent any potential stomach upset in specific cases.

Q. Does Rifagut make you drowsy?

Ans. No, but Rifagut may cause drowsiness in a few cases but it varies with every individual.

Q. What should be the time gap between the consumption of 2 Rifagut doses?

Ans. Ideal time gap of 4-6 hours should be there between two doses to avoid Rifagut toxicity or overdose.

Q. Should I complete the whole cycle of the medicine even if cured?

Ans. Rifagut should be consumed as prescribed by the doctor and in case of any severity of symptoms, immediate medical help or consultation should be taken. And the doctor should be the one to decide when and how to stop the cycle of Rifagut.

Q. Does Rifagut effect my menstrual cycle?

Ans. No, it generally doesn’t affect the menstrual cycle but one should always consult the doctor in case of pre existing menstrual problems before consuming the drug

Q. Is Rifagut safe for children?

Ans. Rifagut should not be administered in children without proper consultation and recommendation by the Paediatrician.

Q. Are there any symptoms that I should consider before taking Rifagut?

Ans. Any liver disorder, drug intolerance or allergic reactions are to be taken into consideration before taking Rifagut.

Q. Is Rifagut legal in India?

Ans. Yes, it is legal in India.

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Disclaimer – The information provided above is to the best of our research and knowledge. However, you are recommended to consult a physician before consuming the drug.

Authored by –

Reviewed and Edited by Dr. Pradeep - Clinical Research Coordinator
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