Sodium Valproate: Uses, Dosage, Price, Side Effects, Precautions & More

What is Sodium Valproate?

Sodium Valproate is an anti-epileptic medication generally used for the treatment of epilepsy and some brain disorders.

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Uses of Sodium Valproate

Sodium Valproate is used in the treatment of:

  • Epilepsy
  • Bipolar disorder
  • Migraine
  • Mania
  • seizures
Other medicine's Uses: Sodium Thiosulphate Uses | Sulfasalazine Uses

How Does Sodium Valproate Work?

Sodium Valproate acts by controlling the abnormal and increased activity of nerve cells inside the brain. This results in less nerve transmission and improving symptoms of epilepsy and certain brain disorders.

How to Take Sodium Valproate?

Sodium Valproate tablet must be swallowed as a whole with a glass of water. You must not chew, crush or break the tablet while taking it. If you are prescribed with syrup form them measure the quantity prescribed with measuring cup and drink it. Always shake the bottle before use. You may consume Sodium Valproate on an empty or full stomach.

Sodium Valproate Price In India

SpecificsSodium Valproate Price
25 kg Pouch Pack1000/KG

Common Dosage for Sodium Valproate?

Sodium Valproate is generally prescribed once or twice, daily. Your doctor may alter your dosage and its frequency depending upon the severity of your condition.

When to Avoid Sodium Valproate?

Avoid Sodium Valproate if:

  • You are allergic to any component of Sodium Valproate
  • You have urea cycle disorders
  • You have liver disorders
  • You have mitochondrial dysfunction
  • You have depression

Side-Effects of Sodium Valproate

Some of the reported side effects of Sodium Valproate are:

  • Appetite loss
  • Nausea
  • Vomiting
  • Sleepiness
  • Hair loss
  • Increased Weight
  • Abnormal liver functions
  • Upset stomach
  • Diarrhea
  • Blurred vision
  • Feeling shaky
  • Aggression
  • confusion
Also Read: Tetracycline Side Effect | Trimethoprim Side Effect

Effects of Sodium Valproate on Organs?

Long-term use of Sodium Valproate is not safe for the patients with kidney and liver disease. Your doctor may adjust your dose as per your requirement.

Are There Any Reported Allergic Reactions?

Some of the common allergic reactions reported with Sodium Valproate are hives, difficulty breathing, and swelling of your face, lips, tongue, or throat.

Drug Interactions to Be Careful About

Some of the drug interactions one needs to be careful about while consuming Sodium Valproate are:

  • Lamotrigine
  • Blood thinning medications
  • Metoclopramide
  • Imipenem
  • Ethinyl Estradiol
  • Doripenem
  • Meropenem
  • Ritonavir

Effects/Results After Consuming Sodium Valproate

The effect of Sodium Valproate can be observed within 2 hours of administration. The effect of this medication lasts up to 24 hours.


Is Sodium Valproate addictive?

Sodium Valproate is generally not addictive in nature.

Can I have Sodium Valproate with alcohol?

It is better to avoid alcohol when on Sodium Valproate. Consult your doctor about limiting alcohol with this medication. Co-consumption of alcohol with Sodium Valproate causes excessive sleepiness and drowsiness.

Any particular food item to be avoided?

Carbonated drinks must be avoided while on this medication. Further, consult your doctor regarding the other foods to be avoided.

Can I have Sodium Valproate when pregnant?

In most cases, it is not safe to take Sodium Valproate if you are pregnant or planning a pregnancy. Consult your doctor if it is absolutely necessary to take this medication.

Can I have Sodium Valproate when feeding a baby?

Sodium Valproate is known to pass in mother’s milk to the baby. Consult your doctor if it is absolutely necessary to take this medication while you are breastfeeding.

Can I drive after taking Sodium Valproate?

It is generally safe to drive while taking Sodium Valproate. However, if you experience drowsiness, dizziness, a headache or any side effect that alters your consciousness then it may not be safe to drive.

What happens if I overdose on Sodium Valproate?

An overdose of Sodium Valproate will not improve your symptoms. It may even cause serious side-effects like coma, irregular heart rat, drowsiness, etc. Consult your doctor immediately in case of overdose.

What happens if I eat expired Sodium Valproate?

If by mistake you consume a dose of expired Sodium Valproate, the chances of harm are very less. It is advised to check the label for expiry date always before use.

What happens if I miss a dose of Sodium Valproate?

As soon as you remember, take the missed dose. However, if it is already time for next dose, carry on with your regular schedule. Do not take a double dose to make up for the missed dose.

Storage Requirements of Sodium Valproate

  • Always store Sodium Valproate at a temperature around 25 degree Celsius
  • Storing in moisture-prone places like bathroom may damage the tablet
  • Place the cap tightly after use of suspension form of this drug
  • Keep Sodium Valproate away from direct heat and sunlight
  • Store it where your children and pets can’t reach

Pro Tips When Taking Sodium Valproate

  • Do not try to self-adjust the dose. Take it in the quantity prescribed by your doctor.
  • Do not share your medication with anyone even if they have a similar condition.
  • Discuss the pros and cons of Sodium Valproate if you are pregnant or planning a pregnancy or if you are breastfeeding.
  • Maintain a minimum gap of 2 hours between consumption of antacids and Sodium Valproate.
  • Always take this tablet on a full stomach or with a glass of milk to avoid stomach upset.
Other medicine's to read: ilver Nitrate
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