What is Verapamil?
Verapamil is a calcium channel blocker. Verapamil is used to treat hypertension (high blood pressure), angina (chest pain), and certain heart rhythm disorders.
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Uses of Verapamil
Verapamil is used for:
- Prevention of nodal arrhythmias (e.g., SVT)
- Rate control in atrial fibrillation.
- Verapamil also has been used in the prophylaxis of migraine headaches.
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How does Verapamil work?
- Verapamil works by relaxing the muscles of your heart and blood vessels, so the heart does not have to pump as hard.
- Verapamil also increases the supply of blood and oxygen to the heart and slows electrical activity in the heart to control the heart rate.
How to take Verapamil?
- Verapamil comes as a tablet, an extended-release (long-acting) tablet, and an extended-release (long-acting) capsule to take by mouth.
- The regular tablet is usually taken three to four times a day.
- The extended-release tablets and capsules are usually taken once or twice a day.
- Oral administration of Verapamil reduces peripheral vascular resistance and blood pressure, often with minimal changes in heart rate.
- The immediate-release tablets are also used alone or with other medications to prevent and treat irregular heartbeats.
- Do not crush, chew, or break an extended-release tablet or capsule. Swallow it whole.
Verapamil Price In India
|40mg Strip of 10 Tablets||Rs 6.72|
|80mg Strip of 10 Tablets||Rs 12.40|
|120mg Strip of 10 Tablets||Rs 20.43|
|240mg Strip of 10 Tablets||Rs 39.00|
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Common Dosage of Verapamil
- The dosage of Verapamil varies from person to person with respect to the disease and weight and age.
- For hypertension, oral tablets dosage is 200 mg initially. Your doctor might increase it to 400 mg.
- The usual dosage for angina is 180 mg orally once a day at bedtime; maximum dosage is 480 mg per day.
- Consult your doctor before taking the medicine.
When to avoid Verapamil?
- If you take disopyramide, avoid taking it within 48 hours before or 24 hours after you take Verapamil.
- Drinking alcohol can further lower your blood pressure and may increase certain side effects of Verapamil.
- Avoid taking aspirin, imatinib, lithium, nefazodone, clonidine, digoxin, flecainide, ivabradine, nicardipine, or quinidine in combination with Verapamil.
- Tuberculosis medicine (isoniazid, rifampin) also needs to be avoided when taken with verapamil.
- Combining simvastatin and Verapamil medications may significantly increase the blood levels of simvastatin. This can increase the risk of side effects such as liver damage.
- Verapamil in combination with hydrocodone may increase the blood levels of hydrocodone.
- Verapamil may increase the blood levels and effects of methadone and requires dose adjustment.
- Combination of Verapamil and metoprolol may lead to swelling of the extremities, weight gain, and shortness of breath or irregular heartbeat.
Precautions while taking Verapamil
- You should not use Verapamil if you have a serious heart condition.
- If you are allergic to Verapamil or to any of its ingredients, stop taking it and consult your doctor.
- In contrast, in patients with congestive heart failure, intravenous Verapamil can cause a marked decrease in contractility and left the ventricular function.
- The major adverse effect of intravenous Verapamil or diltiazem is hypotension, particularly with bolus administration.
- Verapamil may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
Side Effects of Verapamil
Some of the commonly reported side effects of Verapamil are:
- Reduced blood pressure (especially orthostatic hypotension)
- Reduced cardiac output
- Lower extremity edema
- cardiovascular effects (HF, AV block, sinus node depression
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Effects on organs?
- Lung problems – anxiety, sweating, pale skin, wheezing, gasping for breath, cough with foamy mucus.
- Liver problems – loss of appetite, upper stomach pain, tiredness, easy bruising or bleeding, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
- Skin problems- Scalp irritation, rash.
- Heart problems- hypotension, sinus bradycardia, severe tachycardia, edema, atrioventricular (AV) block, peripheral edema.
Storage Requirements for Verapamil
- Keep Verapamil in a dry, airtight container.
- Keep it away from direct heat or moisture.
- Keep it out of reach of the children.
Pro Tips When Taking Verapamil
- Verapamil affects the passage of calcium ions across cell membranes of smooth muscle cells and heart cells.
- When used to treat angina, Verapamil dilates the main coronary blood vessels and reduces the amount of energy and oxygen the heart uses to beat.
- Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.
- If Verapamil makes you dizzy this may affect your ability to drive.
- Avoid alcohol intake while taking Verapamil because it may further lower your blood pressure.
Is Verapamil addictive?
Can I have Verapamil with alcohol?
Any particular food item to be avoided?
Avoid eating grapefruit or drinking grapefruit juice while taking Verapamil.
Can I have Verapamil when pregnant?
Can I have Verapamil while feeding a baby?
Can I drive after taking Verapamil?
Yes, only if you are aware of the effects it has on your thinking ability and alertness.
What happens if I overdose on Verapamil?
You may experience dangerously low blood pressure, slowed heart rate, or slowed digestion.
What happens if I eat expired Verapamil?
Expired medicines may have lost potency and will not be as effective as earlier. Sometimes it can be harmful to the body.
What happens if I miss a dose of Verapamil?
Take the missed dose as soon as you remember it. Skip the missed dose, if it’s time for the next dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
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