Xeljanz (Tofacitinib): Uses, Dosage, Price, Side Effects, Precautions & More

What is Xeljanz?

Xeljanz belongs to the immunomodulatory class of drugs which helps in reducing inflammation and joint damage.

Manufactured By – Pfizer Ltd.

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What does Xeljanz contain?

Xeljanz contains Tofacitinib as the main active ingredient.

What is Xeljanz used for?

Xeljanz (Tofacitinib) is used in the treatment of:

  • Psoriatic arthritis
  • Rheumatoid arthritis
Also Read: Leflunomide Uses

How Does Xeljanz Work?

Xeljanz acts by suppressing the activity of certain chemicals in the body which is responsible for causing inflammation. This leads to a reduced immune response from the body.

How to Take Xeljanz?

Xeljanz tablet must be swallowed as a whole with a glass of water. You must not chew, crush or break the tablet while taking it. You may consume Xeljanz (Tofacitinib) on an empty or full stomach.

Xeljanz Price In India

SpecificsXeljanz Price
5mg Bottle of 60 TabletsRs 35000.00
Also Read: Cosentyx Price | Humulin Price

Common Dosage for Xeljanz?

Xeljanz is generally prescribed one to two times daily. Your doctor may alter your dosage and its frequency depending upon the severity of your condition.

When to Avoid Xeljanz?

Avoid Xeljanz (Tofacitinib) if:

  • You are allergic to any component of Xeljanz
  • You have liver disease
  • You have a blood disorder
  • You are suffering from a kidney disorder
  • You have a low blood cell count
  • You have any current infection

Side-Effects of Xeljanz

Some of the reported side effects of Xeljanz are:

  • Headache
  • Nausea
  • Diarrhea
  • Usual tiredness
  • Vomiting
  • Increased heartbeat
  • Stomach disease
  • Dark colored urination
  • Yellow eyes or skin
  • Heartburn
Also Read: Xifaxan Side Effect | Zinc Sulphate Side Effect | Zyprexa Side Effect

Effects of Xeljanz (Tofacitinib) on Organs?

Long-term use of Xeljanz is not safe for the patients with kidney and liver disease. Your doctor may adjust your dose as per your requirement.

Are There Any Reported Allergic Reactions?

Some of the common allergic reactions reported with Xeljanz (Tofacitinib) are:

  • hives,
  • difficulty breathing, and
  • swelling of your face, lips, tongue, or throat.

Drug Interactions to Be Careful About

One needs to be careful about the following drug interactions with Xeljanz (Tofacitinib):

  • Live vaccines
  • Efalizumab
  • Natalizumab
  • Tofacitinib
  • Fingolimod
  • Ocrelizumab
  • Amiodarone
  • Abatacept
  • Azathioprine
  • Phenobarbital
  • Phenytoin

Effects/Results After Consuming Xeljanz

The effect of Xeljanz (Tofacitinib) can be observed within 1 hour of administration but it will take longer to show its full effect. Your disease symptoms will start to improve after taking Xeljanz.


Is Xeljanz addictive?

Xeljanz is not addictive in nature.

Can I have Xeljanz (Tofacitinib) with alcohol?

It is better to avoid alcohol when on Xeljanz. Consult your doctor about limiting alcohol with this medication. Co-consumption of alcohol with Xeljanz causes excessive sleepiness and drowsiness.

Any particular food item to be avoided?

You must consult your doctor regarding the foods to be avoided.

Can I have Xeljanz (Tofacitinib) when pregnant?

In most cases, it is not safe to take Xeljanz if you are pregnant or planning a pregnancy. Consult your doctor if it is absolutely necessary to take this medication.

Can I have Xeljanz when feeding a baby?

Xeljanz (Tofacitinib) is known to pass in mother’s milk to the baby. Consult your doctor if it is absolutely necessary to take this medication while you are breastfeeding.

Can I drive after taking Xeljanz?

It is generally safe to drive while taking Xeljanz. However, if you experience drowsiness, dizziness, a headache or any side effect that alters your consciousness then it may not be safe to drive.

What happens if I overdose on Xeljanz (Tofacitinib)?

An overdose of Xeljanz will not improve your symptoms. It may even cause serious side-effects like stomach pain, nausea, vomiting, and diarrhea. Consult your doctor immediately in case of overdose.

What happens if I eat expired Xeljanz?

If by mistake you consume a dose of expired Xeljanz (Tofacitinib), the chances of harm are very less. It is advised to check the label for expiry date always before use.

What happens if I miss a dose of Xeljanz?

As soon as you remember, take the missed dose. However, if it is already time for next dose, carry on with your regular schedule. Do not take a double dose to make up for the missed dose.

Storage Requirements of Xeljanz (Tofacitinib)

  • Always store Xeljanz at a temperature around 25 degree Celsius
  • Storing in moisture-prone places like bathroom may damage the tablet
  • Keep Xeljanz away from direct heat and sunlight
  • Store it where your children and pets can’t reach

Pro Tips When Taking Xeljanz

  • Do not try to self-adjust the dose. Take it in the quantity prescribed by your doctor.
  • Do not share your medication with anyone even if they have a similar condition.
  • Discuss the pros and cons of Xeljanz (Tofacitinib) if you are pregnant or planning a pregnancy or if you are breastfeeding.
  • Share your complete medical history with your doctor before taking Xeljanz.
  • Avoid contact with people who have any infection as you are likely to get one.

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