Zanaflex: Uses, Dosage, Side Effects , Price, Composition, Precautions & More

What is Zanaflex?

  • Zanaflex contains “tizanidine” as its active ingredient.
  • Zanaflex belong to a group of medicines called skeletal muscle relaxants.
Check Out: Myra Medicines Offers | 1mg Offers | Practo Offers

Uses of Zanaflex

  • Zanaflex is used for the treatment of muscle spasms resulting from multiple sclerosis, injury or diseases of the spinal cord.
Read more: Mercaptopurine Uses

 Zanaflex Composition

  • Zanaflex tablets contain the active ingredient, tizanidine hydrochloride (4.58 mg equivalent to 4 mg tizanidine base),
  • Inactive ingredients: colloidal silicon dioxide, stearic acid, microcrystalline cellulose and anhydrous lactose.
Know more: Novolog Composition

How does Zanafl Zanaflex ex work?

  • Zanaflex works by blocking nerve impulses (pain sensations) that are sent to the brain.
Also check out: Zocor Price

How to Take Zanaflex?

  • Zanaflex is available in the form of 2, 4, and 6 mg capsules and 4mg tablets.
  • Zanaflex tablets and capsules should be consumed with water.
  • The way the tablets or capsules should be consumed with or without food must be decided after consultation with your doctor.
  • Do not crush, chew or dissolve the capsules/tablets.

Common Dosage for Zanaflex?

  • Recommended starting dose for Zanaflex is 2mg.
  • Treatment can be repeated at 6-8 hour intervals, as needed, to a maximum of three doses in a day.
  • Dosage can be increased by 2 – 4 mg per dose, with 1 – 4 days between increases.
  • Maximum dose per day – 36 mg.
Read more: Zocor Dosage

When to Avoid Zanaflex?

Zanaflex should be avoided or used with caution in:

  • Patients with allergy to Zanaflex
Read more: Revlimid Precaution

Side-effects of Zanaflex?

  • In addition to its intended uses, it may cause few undesirable side effects as well.
  • Low blood pressure
  • Sedation
  • Drowsiness, tiredness, dizziness
  • Hallucinations
  • Increase of blood pressure if the patient stops taking medicine abruptly
  • Dry mouth
  • Decrease or increase in heart rate
  • Sleep disorders
  • Nausea
  • Stomach upset
  • Muscle weakness

Effect on organs?

  • Dose adjustment is required in patients liver and kidney dysfunction.

Reported Allergic Reactions?

  • Report to your doctor if you are allergic to any of its ingredients.
  • Signs of allergic reaction include:
  • Rashes/itching of skin
  • Shortness of breath
  • Swelling of face, lips, tongue, or throat
  • Loss of consciousness

Drug Interactions to Be Careful About

  • Zanaflex can interact with other drugs, vitamin supplements and herbal products. It is always advised that you must inform the physician about all the drugs/over the counter products used before using Zanaflex.
  • Drugs that can interact with Zanaflex include –
  • Fluvoxamine
  • Ciprofloxacin
  • Zileuton, fluoroquinolones other than strong CYP1A2 inhibitors
  • Antiarrythmics – amiodarone, mexiletine, propafenone, and verapamil
  • Cimetidine, famotidine
  • Oral contraceptives
  • Acyclovir
  • Ticlopidine
  • Oral contraceptives
  • CNS depressants (e.g., benzodiazepines, opioids, tricyclic antidepressants)
  • α2-adrenergic agonists (used to treat high blood pressure)

Shows Effects / Results In:

Zanaflex shows therapeutic effects within 1-2 hours of oral administration.

Storage of Zanaflex:

  • Store at cool and dry place away from direct heat and moisture.
  • Do not freeze the medicine.
  • Keep medicines away from children and pets.

Pro Tips When Taking Zanaflex:

  • Do not get up immediately from lying down position as Zanaflex can lead to posture related fall in blood pressure.
  • Do not stop taking the drug abruptly as it may lead to adverse withdrawal symptoms.
  • Always inform your doctor if you are planning to conceive while taking Zanaflex.

Frequently Asked Questions

Is Zanaflex addictive?

  • Zanaflex is not addictive.

Can I have Zanaflex with alcohol?

  • No

Any particular food item to be avoided?

  • No

Can I have Zanaflex when pregnant?

  • Zanaflex should be given to pregnant women only if the benefit outweighs the risk to the unborn fetus

Can I have Zanaflex when feeding a baby?

  • No

Can I drive after taking Zanaflex?

  • Zanaflex can cause fall in blood pressure and cause sedation as a side effect. Make sure you are not affected before you drive.

What happens if I overdose on Zanaflex?

Signs of overdose include lethargy, sleeplessness, confusion and coma.

You must contact your doctor immediately if you have taken an overdose.

What happens if I take expired Zanaflex?

  • A single dose of expired Zanaflex may not cause any major adverse effect. However, the potency of the medicine may well have decreased overtime.

What happens if I miss a dose of Zanaflex?

  • You can take the dose as soon as you remember it but if it’s time for the next dose, avoid taking a double dose.

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